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Gene · 203

AK1: adenylate kinase 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. AK1: adenylate kinase 1. Genes, record 203. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/203

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Gene

Symbol
AK1
HGNC
Name
adenylate kinase 1
HGNC
NCBI Gene ID
203
NCBI Gene
HGNC ID
HGNC:361
HGNC
Ensembl
ENSG00000106992
NCBI Gene
Aliases
ADK, Adk1, CNSHA3, HTL-S-58j
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P00568Adenylate kinase isoenzyme 11945Ensembl, GeneID, HGNC

Source UniProt

Patents50

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1436719P00568Espacenet
JP 2026004568 A2026-01-1436720P00568Espacenet
EP 4650780 A22025-11-199253P00568Espacenet
JP 2025517970 A2025-06-129253P00568Espacenet
JP 2025062604 A2025-04-142846P00568Espacenet
JP 2025062604 A2025-04-142847P00568Espacenet
US 12130292 B22024-10-2925P00568Espacenet
US 11446398 B22022-09-202846P00568Espacenet
US 11446398 B22022-09-202847P00568Espacenet
JP 2022524081 A2022-04-27105817P00568Espacenet

1 to 10 of 50

See all 50 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants635

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleAK1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant32025
P30CA013696Cancer Center Support Grant22025
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)22025
P30CA016056Roswell Park Cancer Center Support Grant22025
P30CA016086Cancer Center Support Grant22025
P30CA016672Cancer Center Support Grant22025
P30CA036727Buffett Cancer Center Support Grant22025
P30EY029220Center Core Grant for Vision Research22025
R01HG002385Long-read sequence and assembly of segmental duplications22025
R01HG010169Sequence resolution of complex human genome structural variation22025

1 to 10 of 635Source NIH's project files

See all 635 nih grants

Papers1,146

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A Practical Workflow for Reliable MALDI-Based Hydrogen/Deuterium Exchange Mass Spectrometry.Mass Spectrom (Tokyo)202642761390PubTator, text miningPubMed
Proteomic characterization of human kinases across tissue types: Implications for kinase-activated drugs.Drug Metab Dispos202642727291PubTator, text miningPubMed
DNA methylation reprogramming of gene regulatory elements is associated with lung metastasis in triple-negative breast cancer.Commun Biol202642481665PubTator, text miningPubMed
Differential expression patterns of selective energy metabolism associated genes in fresh and freeze-thawed bubaline spermatozoa at uniform durations of in vitro capacitation.Cryobiology202642308645PubTator, text miningPubMed
Clinicopathological and molecular characterization of HPV-associated cervical poorly cohesive carcinoma: a rare aggressive entity.J Pathol Clin Res202642289532PubTator, text miningPubMed
Novel statin derivatives as non-competitive inhibitors of human adenylate kinase 1: synthesis, enzyme inhibition, molecular docking, and biological studies.Biochimie202642150648PubTator, text miningPubMed
Actinic keratosis staging in multimodal image data.Comput Methods Programs Biomed202641990405PubTator, text miningPubMed
Investigation of the effects and underlying mechanisms of adenylate kinase 1 on inosine monophosphate deposition in Beijing-You chickens.Poult Sci202641905068PubTator, text miningPubMed
IFFO1 inhibits breast cancer by coordinating mitochondrial fission and fatty acid synthesis via the LaminA/C-PGC1α axis.Oncogenesis202641844580PubTator, text miningPubMed
The Yin-Yang balance of SIRT1 and SIRT2 in cancer metabolic remodeling.Int J Biol Sci202641800243PubTator, text miningPubMed

1 to 10 of 1,146

See all 1,146 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/203

GET https://conductscience.org/api/genes/v1/203/patents?page=2