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Gene · 203068

TUBB: tubulin beta class I

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TUBB: tubulin beta class I. Genes, record 203068. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/203068

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Gene

Symbol
TUBB
HGNC
Name
tubulin beta class I
HGNC
NCBI Gene ID
203068
NCBI Gene
HGNC ID
HGNC:20778
HGNC
Ensembl
ENSG00000196230
NCBI Gene
Aliases
CDCBM6, CSCSC1, M40, MGC16435, OK/SW-cl.56, TUBB1, TUBB5, Tubb5
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P07437Tubulin beta chain44421Ensembl, GeneID, HGNC

Source UniProt

Patents140

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1468528P07437Espacenet
JP 2026004568 A2026-01-1468530P07437Espacenet
JP 2026004568 A2026-01-1468539P07437Espacenet
JP 2026004568 A2026-01-1468542P07437Espacenet
JP 2026004568 A2026-01-1468543P07437Espacenet
JP 2026004568 A2026-01-1468544P07437Espacenet
JP 2026004568 A2026-01-1468551P07437Espacenet
JP 2026004568 A2026-01-1468555P07437Espacenet
EP 4650780 A22025-11-196397P07437Espacenet
EP 4641202 A22025-10-295111P07437Espacenet

1 to 10 of 140

See all 140 patents

Drugs91

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ABT-751CHEMBL20684Tubulin beta inhibitorINHIBITORChEMBL
AGS-16C3FCHEMBL4594455Tubulin disrupting agentDISRUPTING AGENTChEMBL
ANETUMAB RAVTANSINECHEMBL2109629Tubulin inhibitorINHIBITORChEMBL
ANG1005CHEMBL1089636Tubulin inhibitorINHIBITORChEMBL
ANVATABART OPADOTINCHEMBL4297892Tubulin inhibitorINHIBITORChEMBL
APRUTUMAB IXADOTINCHEMBL4650293Tubulin inhibitorINHIBITORChEMBL
ASG-5MECHEMBL2109574Tubulin inhibitorINHIBITORChEMBL
AVE-9633CHEMBL2109266Tubulin inhibitorINHIBITORChEMBL
AZINTUXIZUMAB VEDOTINCHEMBL4297859Tubulin inhibitorINHIBITORChEMBL
BELANTAMAB MAFODOTINCHEMBL4298209Tubulin inhibitorINHIBITORChEMBL

1 to 10 of 91

See all 91 drugs

Trials8,740

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07604766PACLITAXELPHASE3ClinicalTrials.gov
NCT07602907PACLITAXELPHASE2ClinicalTrials.gov
NCT07601737PACLITAXELPHASE2ClinicalTrials.gov
NCT07601178PACLITAXELPHASE2ClinicalTrials.gov
NCT07599163PACLITAXELClinicalTrials.gov
NCT07595770PACLITAXELPHASE2ClinicalTrials.gov
NCT07594548PACLITAXELPHASE1ClinicalTrials.gov
NCT07591467DOCETAXELPHASE3ClinicalTrials.gov
NCT07589972VINORELBINEClinicalTrials.gov
NCT07588698VINCRISTINE SULFATEPHASE2ClinicalTrials.gov

1 to 10 of 8,740

See all 8,740 trials

NIH grants1,820

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTUBB papersNewest fiscal year
P30CA008748Cancer Center Support Grant132025
R01NS058721ACC: Callosal Agenesis as a Window into Common Neurodevelopmental Disorders72025
P30CA016086Cancer Center Support Grant62025
P30CA068485Cancer Center Support Grant62025
P30CA016672Cancer Center Support Grant52025
UL1TR001863Yale Clinical and Translational Science Award52025
P30ES010126UNC Center for Environmental Health and Susceptibility42025
KL2TR001879Institutional Career Development Core32025
P30CA014195Cancer Center Support Grant (CCSG)32025
P30CA054174Mays Cancer Center at UT Health SA32025

1 to 10 of 1,820Source NIH's project files

See all 1,820 nih grants

Papers2,200

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Identification and evaluation of candidate sperm proteins associated with cryopreservation-induced changes in semen quality in Thai native roosters.Poult Sci202642785075PubTator, text miningPubMed
KDM1A/HDAC2-driven epigenetic dysregulation maintains a drug-resistant, relapse-initiating glioblastoma cell niche at the peri-tumoral margin.Biochem Pharmacol202642685875PubTator, text miningPubMed
A Novel Constitutional TUBB Variant Associated With Familial Malformations of Cortical Development.Am J Med Genet A202642631447PubTator, text miningPubMed
Exosomal gene-based predictive model and therapeutic target identification for Alzheimer's disease: A bioinformatics analysis.PLoS One202642475384PubTator, text miningPubMed
Plasma proteome differences between giant cell arteritis and polymyalgia rheumatica: a pilot study.Arthritis Res Ther202642387612PubTator, text miningPubMed
Multi-omics profiling characterizes the primary cilium-related molecular regulatory landscape in systemic lupus erythematosus.Analyst202642312723PubTator, text miningPubMed
Exploring the Potential of Calebin-A in Targeting Obesity-Related Genes and Pathways.J Cell Mol Med202642286733PubTator, text miningPubMed
Integrative multi-omics analysis-based Mendelian randomization identifies association of DNA repair-related genes with oral cancer.Cancer Biomark202642257465PubTator, text miningPubMed
Genetic Identification of Potential Drug Targets for Dental Caries: A Mendelian Randomization Study.Health Sci Rep202642163948PubTator, text miningPubMed
Unraveling novel therapeutic targets for diffuse large B-cell lymphoma: a plasma multi-omics study.Front Pharmacol202642147334PubTator, text miningPubMed

1 to 10 of 2,200

See all 2,200 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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