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C9orf72: C9orf72-SMCR8 complex subunit

1 protein, 76 patents, 0 drugs, 0 trials, 3,065 NIH grants and 7,313 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolC9orf72HGNC
NameC9orf72-SMCR8 complex subunitHGNC
NCBI Gene ID203228NCBI Gene
HGNC IDHGNC:28337HGNC
EnsemblENSG00000147894NCBI Gene
AliasesALSFTD, DENND9, DENNL72, FTDALS, FTDALS1, MGC23980NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q96LT7Guanine nucleotide exchange factor C9orf724814Ensembl, GeneID, HGNCUniProt

Patents 76

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026077682 A2026-05-1314Q96LT7Espacenet
JP 2026004568 A2026-01-1441551Q96LT7Espacenet
JP 2025174957 A2025-11-2827Q96LT7Espacenet
JP 2025174957 A2025-11-2829Q96LT7Espacenet
EP 4641202 A22025-10-295743Q96LT7Espacenet
JP 2025111747 A2025-07-30141Q96LT7Espacenet
JP 2025521154 A2025-07-0829Q96LT7Espacenet
JP 2025521154 A2025-07-0831Q96LT7Espacenet
JP 2025062601 A2025-04-1490Q96LT7Espacenet
JP 2025032204 A2025-03-1125409Q96LT7Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3065

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P01AG019724Frontotemporal Dementia: Genes, Images, and Emotions1572,025NIH's project files
U24AG021886National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)672,025NIH's project files
U19AG063911ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration, Cycle 2 (ALLFTD2)452,025NIH's project files
P30AG062422New Approaches to Dementia Heterogeneity432,025NIH's project files
ZIAAG000933Genetic etiology of Amyotrophic Lateral Sclerosis432,025NIH's project files
ZIAAG000934ALZHEIMERS RESEARCH PROJECT: Genetic etiology of Fronto-Temporal Dementia, a dementia related to Alzheimer's disease322,025NIH's project files
T32AG023481Multidisciplinary Research Fellowship in Alzheimer’s disease and Related Dementias292,025NIH's project files
U54NS092091Clinical Research in ALS and Related Disorders for Therapeutic Development (CReATe)272,025NIH's project files
P30AG062421Massachusetts Alzheimer's Disease Research Center (MADRC)232,025NIH's project files
R01NS101986Understanding Frontotemporal Dementia Using Drosophila and iPSC Models232,025NIH's project files

Papers 7313

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42816700PubTator, text miningPubMed
42808521PubTator, text miningPubMed
42799858PubTator, text miningPubMed
42791439PubTator, text miningPubMed
42789481PubTator, text miningPubMed
42789089PubTator, text miningPubMed
42786195PubTator, text miningPubMed
42782801PubTator, text miningPubMed
42782733PubTator, text miningPubMed
42780028PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license