Gene · 2041
EPHA1: EPH receptor A1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. EPHA1: EPH receptor A1. Genes, record 2041. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2041
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P21709 | Ephrin type-A receptor 1 | 976 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents33
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 45072 | P21709 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 2955 | P21709 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 366 | P21709 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 2517 | P21709 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 142 | P21709 | Espacenet |
| EP 4641203 A2 | 2025-10-29 | 98 | P21709 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1411 | P21709 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1411 | P21709 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 366 | P21709 | Espacenet |
| JP 2025517967 A | 2025-06-12 | 98 | P21709 | Espacenet |
1 to 10 of 33
See all 33 patentsDrugs1
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action |
|---|---|---|---|
| VANDETANIB | CHEMBL24828 | Ephrin receptor inhibitor | INHIBITOR |
Source ChEMBL
Trials97
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT06482086 | VANDETANIB | PHASE2 | ClinicalTrials.gov | |
| NCT04211337 | VANDETANIB | PHASE3 | 2024-06-13 | ClinicalTrials.gov |
| NCT03630120 | VANDETANIB | PHASE2 | 2021-01-22 | ClinicalTrials.gov |
| NCT03291379 | VANDETANIB | EARLY_PHASE1 | 2021-02-03 | ClinicalTrials.gov |
| NCT02638428 | VANDETANIB | PHASE2 | ClinicalTrials.gov | |
| NCT02530411 | VANDETANIB | PHASE2 | ClinicalTrials.gov | |
| NCT02495103 | VANDETANIB | PHASE1/PHASE2 | 2021-01-26 | ClinicalTrials.gov |
| NCT02299999 | VANDETANIB | PHASE2 | ClinicalTrials.gov | |
| NCT02117167 | VANDETANIB | PHASE2 | ClinicalTrials.gov | |
| NCT02109250 | VANDETANIB | ClinicalTrials.gov |
1 to 10 of 97
See all 97 trialsNIH grants2,640
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | EPHA1 papers | Newest fiscal year |
|---|---|---|---|
| U24AG021886 | National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD) | 63 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 23 | 2025 |
| P01AG019724 | Frontotemporal Dementia: Genes, Images, and Emotions | 16 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 14 | 2025 |
| P01AG026276 | Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study | 12 | 2025 |
| U19AG024904 | Alzheimer's Disease Neuroimaging Initiative (ADNI4) | 10 | 2025 |
| U24AG056270 | National Institute on Aging Alzheimer's Disease Family-Based Study (NIA-AD FBS) | 10 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 9 | 2025 |
| R01NS017950 | Precursors of Stroke Incidence and Prognosis | 9 | 2025 |
| P30CA030199 | Cancer Center Support Grant (CCSG) | 8 | 2025 |
1 to 10 of 2,640Source NIH's project files
See all 2,640 nih grantsPapers3,104
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Gravity-driven millifluidic platform for magnetic solid-phase extraction of Enterocytozoon hepatopenaei DNA from complex shrimp hepatopancreas. | Talanta | 2027 | 42721738 | PubTator, text mining | PubMed |
| Genome-wide transcriptomics and a machine learning-based random forest model identify novel biomarkers to predict phenotypic variability in Wilson disease. | Hum Immunol | 2026 | 42826579 | PubTator, text mining | PubMed |
| Receptor tyrosine kinase signaling in mammalian eye development. | Dev Biol | 2026 | 42762961 | PubTator, text mining | PubMed |
| Association between Alzheimer's disease-related genes and neurodegenerative blood-based biomarkers in Indian adults. | Front Aging Neurosci | 2026 | 42688218 | PubTator, text mining | PubMed |
| Circulating Ephrin-Eph Signaling Reflects Interstitial Fibrosis and Tubular Atrophy in Diabetic Kidney Disease. | Clin J Am Soc Nephrol | 2026 | 42627699 | PubTator, text mining | PubMed |
| Synthesis and antitumoral evaluation of 3',4'-unsaturated nucleoside analogues bearing a chlorinated remdesivir-like base. | Bioorg Chem | 2026 | 42607445 | PubTator, text mining | PubMed |
| Proteomic signatures of protected APOE ε4 carriers reveal causal pathways associated with delayed Alzheimer's disease onset. | Alzheimers Dement | 2026 | 42592812 | PubTator, text mining | PubMed |
| The Interaction between the Tyrosine Kinase Receptor EphA2 and RNF5: Structural Insights from an In Silico Approach. | Comput Struct Biotechnol J | 2026 | 42491429 | PubTator, text mining | PubMed |
| [From clinical benefit to mechanism analysis: research progress on the combined intervention of intelligence three-needling and other therapies in vascular dementia]. | Zhen Ci Yan Jiu | 2026 | 42482588 | PubTator, text mining | PubMed |
| Primary Cilia as Integrative Hubs of Metabolic Signaling in Type 2 Diabetes: Inter-Organ Evidence From Central, Peripheral, and Pancreatic Islet Tissues. | J Cell Physiol | 2026 | 42436646 | PubTator, text mining | PubMed |
1 to 10 of 3,104
See all 3,104 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2041
GET https://conductscience.org/api/genes/v1/2041/patents?page=2