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Gene · 2041

EPHA1: EPH receptor A1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. EPHA1: EPH receptor A1. Genes, record 2041. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2041

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Gene

Symbol
EPHA1
HGNC
Name
EPH receptor A1
HGNC
NCBI Gene ID
2041
NCBI Gene
HGNC ID
HGNC:3385
HGNC
Ensembl
ENSG00000146904
NCBI Gene
Aliases
EPH, EPHT, EPHT1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P21709Ephrin type-A receptor 19764Ensembl, GeneID, HGNC

Source UniProt

Patents33

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1445072P21709Espacenet
EP 4650780 A22025-11-192955P21709Espacenet
EP 4640849 A22025-10-29366P21709Espacenet
EP 4641201 A22025-10-292517P21709Espacenet
EP 4641202 A22025-10-29142P21709Espacenet
EP 4641203 A22025-10-2998P21709Espacenet
JP 2025529142 A2025-09-041411P21709Espacenet
US 12371689 B22025-07-291411P21709Espacenet
JP 2025519096 A2025-06-24366P21709Espacenet
JP 2025517967 A2025-06-1298P21709Espacenet

1 to 10 of 33

See all 33 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
VANDETANIBCHEMBL24828Ephrin receptor inhibitorINHIBITOR

Source ChEMBL

Trials97

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06482086VANDETANIBPHASE2ClinicalTrials.gov
NCT04211337VANDETANIBPHASE32024-06-13ClinicalTrials.gov
NCT03630120VANDETANIBPHASE22021-01-22ClinicalTrials.gov
NCT03291379VANDETANIBEARLY_PHASE12021-02-03ClinicalTrials.gov
NCT02638428VANDETANIBPHASE2ClinicalTrials.gov
NCT02530411VANDETANIBPHASE2ClinicalTrials.gov
NCT02495103VANDETANIBPHASE1/PHASE22021-01-26ClinicalTrials.gov
NCT02299999VANDETANIBPHASE2ClinicalTrials.gov
NCT02117167VANDETANIBPHASE2ClinicalTrials.gov
NCT02109250VANDETANIBClinicalTrials.gov

1 to 10 of 97

See all 97 trials

NIH grants2,640

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleEPHA1 papersNewest fiscal year
U24AG021886National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)632025
P30CA016672Cancer Center Support Grant232025
P01AG019724Frontotemporal Dementia: Genes, Images, and Emotions162025
P30CA008748Cancer Center Support Grant142025
P01AG026276Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study122025
U19AG024904Alzheimer's Disease Neuroimaging Initiative (ADNI4)102025
U24AG056270National Institute on Aging Alzheimer's Disease Family-Based Study (NIA-AD FBS)102025
P30CA046934University of Colorado Cancer Center Support Grant92025
R01NS017950Precursors of Stroke Incidence and Prognosis92025
P30CA030199Cancer Center Support Grant (CCSG)82025

1 to 10 of 2,640Source NIH's project files

See all 2,640 nih grants

Papers3,104

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Gravity-driven millifluidic platform for magnetic solid-phase extraction of Enterocytozoon hepatopenaei DNA from complex shrimp hepatopancreas.Talanta202742721738PubTator, text miningPubMed
Genome-wide transcriptomics and a machine learning-based random forest model identify novel biomarkers to predict phenotypic variability in Wilson disease.Hum Immunol202642826579PubTator, text miningPubMed
Receptor tyrosine kinase signaling in mammalian eye development.Dev Biol202642762961PubTator, text miningPubMed
Association between Alzheimer's disease-related genes and neurodegenerative blood-based biomarkers in Indian adults.Front Aging Neurosci202642688218PubTator, text miningPubMed
Circulating Ephrin-Eph Signaling Reflects Interstitial Fibrosis and Tubular Atrophy in Diabetic Kidney Disease.Clin J Am Soc Nephrol202642627699PubTator, text miningPubMed
Synthesis and antitumoral evaluation of 3',4'-unsaturated nucleoside analogues bearing a chlorinated remdesivir-like base.Bioorg Chem202642607445PubTator, text miningPubMed
Proteomic signatures of protected APOE ε4 carriers reveal causal pathways associated with delayed Alzheimer's disease onset.Alzheimers Dement202642592812PubTator, text miningPubMed
The Interaction between the Tyrosine Kinase Receptor EphA2 and RNF5: Structural Insights from an In Silico Approach.Comput Struct Biotechnol J202642491429PubTator, text miningPubMed
[From clinical benefit to mechanism analysis: research progress on the combined intervention of intelligence three-needling and other therapies in vascular dementia].Zhen Ci Yan Jiu202642482588PubTator, text miningPubMed
Primary Cilia as Integrative Hubs of Metabolic Signaling in Type 2 Diabetes: Inter-Organ Evidence From Central, Peripheral, and Pancreatic Islet Tissues.J Cell Physiol202642436646PubTator, text miningPubMed

1 to 10 of 3,104

See all 3,104 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2041

GET https://conductscience.org/api/genes/v1/2041/patents?page=2