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Gene · 2044

EPHA5: EPH receptor A5

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. EPHA5: EPH receptor A5. Genes, record 2044. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2044

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Gene

Symbol
EPHA5
HGNC
Name
EPH receptor A5
HGNC
NCBI Gene ID
2044
NCBI Gene
HGNC ID
HGNC:3389
HGNC
Ensembl
ENSG00000145242
NCBI Gene
Aliases
CEK7, EHK-1, EHK1, EK7, HEK7, Hek7, TYRO4
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P54756Ephrin type-A receptor 51,0372Ensembl, GeneID, HGNC

Source UniProt

Patents27

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
US 12662541 B22026-06-2341P54756Espacenet
JP 2026004568 A2026-01-1445081P54756Espacenet
EP 4641201 A22025-10-292444P54756Espacenet
JP 2025529142 A2025-09-041416P54756Espacenet
US 12371689 B22025-07-291416P54756Espacenet
JP 2025517969 A2025-06-122444P54756Espacenet
JP 2024540694 A2024-10-3141P54756Espacenet
EP 4426745 A22024-09-1141P54756Espacenet
KR 1020240131324 A2024-08-3041P54756Espacenet
JP 2024514157 A2024-03-28216P54756Espacenet

1 to 10 of 27

See all 27 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
VANDETANIBCHEMBL24828Ephrin receptor inhibitorINHIBITOR

Source ChEMBL

Trials97

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06482086VANDETANIBPHASE2ClinicalTrials.gov
NCT04211337VANDETANIBPHASE32024-06-13ClinicalTrials.gov
NCT03630120VANDETANIBPHASE22021-01-22ClinicalTrials.gov
NCT03291379VANDETANIBEARLY_PHASE12021-02-03ClinicalTrials.gov
NCT02638428VANDETANIBPHASE2ClinicalTrials.gov
NCT02530411VANDETANIBPHASE2ClinicalTrials.gov
NCT02495103VANDETANIBPHASE1/PHASE22021-01-26ClinicalTrials.gov
NCT02299999VANDETANIBPHASE2ClinicalTrials.gov
NCT02117167VANDETANIBPHASE2ClinicalTrials.gov
NCT02109250VANDETANIBClinicalTrials.gov

1 to 10 of 97

See all 97 trials

NIH grants880

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleEPHA5 papersNewest fiscal year
P30CA008748Cancer Center Support Grant122025
P30CA016672Cancer Center Support Grant92025
P30CA022453CANCER CENTER SUPPORT GRANT32025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202832025
P30CA069533OHSU Knight Cancer Institute32025
P30CA072720Cancer Center Support Grant32025
T32GM007019Clinical Therapeutics32025
U10CA180820ECOG-ACRIN Network Group Operations Center32025
U10CA180821Alliance for Clinical Trials in Oncology Operations Center - GY11 Funded Extension32025
P30AG066444Alzheimer's Disease Research Center22025

1 to 10 of 880Source NIH's project files

See all 880 nih grants

Papers903

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Why pharmacogenomic biomarkers for chemotherapy-induced peripheral neuropathy fail: a systematic review of genetic associations, replication, and clinical translation.Front Pharmacol202642494534PubTator, text miningPubMed
Genome wide association study meta-analysis of neuropathologic lesions of Alzheimer's disease and related dementias in a multi-site autopsy cohort.PLoS Genet202642371968PubTator, text miningPubMed
[Molecular characteristics for poor prognosis related renal cell carcinoma with lymph metastases].Beijing Da Xue Xue Bao Yi Xue Ban202642287060PubTator, text miningPubMed
Real-world-data for phenotypes and genotypes of rare monogenic genetic epilepsies and genes of uncertain significance for epilepsy.Epilepsia Open202642220229PubTator, text miningPubMed
Comparative Analysis of Homologous Recombination Repair Status Across Gynecologic and Breast Cancers in Chinese Populations.Curr Cancer Drug Targets202641935348PubTator, text miningPubMed
ORANGE: a machine learning approach for modeling tissue-specific aging from transcriptomic data.Brief Bioinform202641766649PubTator, text miningPubMed
The Paradox of Senescence in Glioblastoma: SASP as an Emerging Cancer Hallmark.Cancers (Basel)202641749804PubTator, text miningPubMed
Single-cell transcriptomics revealed molecular vulnerability in a human midbrain-like organoid model of Parkinson's disease.iScience202641727181PubTator, text miningPubMed
Genome wide association study meta-analysis of neuropathologic lesions of Alzheimer's disease and related dementias in a multi-site autopsy cohort.medRxiv202641646826PubTator, text miningPubMed
Small intestinal SMARCA4-deficient undifferentiated carcinoma with intussusception: A case report.Oncol Lett202641383973PubTator, text miningPubMed

1 to 10 of 903

See all 903 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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