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Gene · 2045

EPHA7: EPH receptor A7

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. EPHA7: EPH receptor A7. Genes, record 2045. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2045

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Gene

Symbol
EPHA7
HGNC
Name
EPH receptor A7
HGNC
NCBI Gene ID
2045
NCBI Gene
HGNC ID
HGNC:3390
HGNC
Ensembl
ENSG00000135333
NCBI Gene
Aliases
EHK-3, EHK3, EK11, HEK11, Hek11
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q15375Ephrin type-A receptor 79987Ensembl, GeneID, HGNC

Source UniProt

Patents70

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-198604Q15375Espacenet
EP 4641201 A22025-10-298762Q15375Espacenet
JP 2025147176 A2025-10-064820Q15375Espacenet
JP 2025529142 A2025-09-041418Q15375Espacenet
JP 2025529142 A2025-09-046274Q15375Espacenet
US 12371689 B22025-07-291418Q15375Espacenet
US 12371689 B22025-07-296274Q15375Espacenet
JP 2025517969 A2025-06-128762Q15375Espacenet
JP 2025517970 A2025-06-128604Q15375Espacenet
JP 2025028160 A2025-02-284820Q15375Espacenet

1 to 10 of 70

See all 70 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
VANDETANIBCHEMBL24828Ephrin receptor inhibitorINHIBITOR

Source ChEMBL

Trials97

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06482086VANDETANIBPHASE2ClinicalTrials.gov
NCT04211337VANDETANIBPHASE32024-06-13ClinicalTrials.gov
NCT03630120VANDETANIBPHASE22021-01-22ClinicalTrials.gov
NCT03291379VANDETANIBEARLY_PHASE12021-02-03ClinicalTrials.gov
NCT02638428VANDETANIBPHASE2ClinicalTrials.gov
NCT02530411VANDETANIBPHASE2ClinicalTrials.gov
NCT02495103VANDETANIBPHASE1/PHASE22021-01-26ClinicalTrials.gov
NCT02299999VANDETANIBPHASE2ClinicalTrials.gov
NCT02117167VANDETANIBPHASE2ClinicalTrials.gov
NCT02109250VANDETANIBClinicalTrials.gov

1 to 10 of 97

See all 97 trials

NIH grants821

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleEPHA7 papersNewest fiscal year
P30CA016672Cancer Center Support Grant162025
P30CA008748Cancer Center Support Grant112025
P30CA006927Comprehensive Cancer Center Program at Fox Chase32025
U10AA008401Collaborative Study on the Genetics of Alcoholism (COGA).32025
ZIABC011091Cancer Genomics Technology Development32025
P30CA006973Regional Oncology Research Center22025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant22025
P30CA030199Cancer Center Support Grant (CCSG)22025
P30CA033572Cancer Center Support Grant22025
P30CA068485Cancer Center Support Grant22025

1 to 10 of 821Source NIH's project files

See all 821 nih grants

Papers1,016

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Multi-omics-guided identification of blood-entering bioactive components and candidate responsive targets of Shugan Jianpi Tiaochang Pill against colorectal adenoma.Phytomedicine202642607381PubTator, text miningPubMed
Multi-Ancestry Genome-Wide Association with Fine-Mapping Identifies Novel Loci for Pigment Dispersion Syndrome and Pigmentary Glaucoma.Ophthalmol Glaucoma202642508691PubTator, text miningPubMed
Methylation-based biomarkers from thin-prep cytology test samples for early detection of cervical cancer: application and clinical potential.Clin Epigenetics202642169140PubTator, text miningPubMed
HPV E6/E7 mRNA vs. HPV DNA in co-testing with ThinPrep cytology for cervical cancer screening: a prospective observational diagnostic accuracy study of methylation biomarkers.J Gynecol Oncol202642135963PubTator, text miningPubMed
miR-196a-5p affects the progression of polycystic ovary syndrome by targeting EPHA7.J Mol Histol202642018244PubTator, text miningPubMed
Integrated Immune and Molecular Profiling Identifies Prognostic Subgroups and Therapeutic Targets in Chondrosarcoma.Int J Mol Sci202641752158PubTator, text miningPubMed
Single-Cell Analysis Reveals Epithelial Heterogeneity and Tumor Microenvironment Characteristics During the Malignant Progression of Colorectal Cancer.Biomedicines202641751270PubTator, text miningPubMed
Oligoclonal B cell expansion and passenger fusion genes predict response to Nivolumab in recurrent ovarian cancer: phase II Kyoto trial.Cancer Immunol Immunother202641591474PubTator, text miningPubMed
Primary Cutaneous CD30-Positive Lymphoproliferative Disorder With Gamma-Delta T-Cells: A Molecular-Annotated Case With a Classic Clinical Appearance and Behavior.J Cutan Pathol202641387293PubTator, text miningPubMed
Clinical significance and biological function of miR-3613-3p in glioma.Neurol Res202640890969PubTator, text miningPubMed

1 to 10 of 1,016

See all 1,016 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2045

GET https://conductscience.org/api/genes/v1/2045/patents?page=2