Gene · 2052
EPHX1: epoxide hydrolase 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. EPHX1: epoxide hydrolase 1. Genes, record 2052. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2052
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P07099 | Epoxide hydrolase 1 | 455 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents151
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 45137 | P07099 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 45138 | P07099 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 2801 | P07099 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 2367 | P07099 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 2367 | P07099 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 2801 | P07099 | Espacenet |
| US 11694765 B2 | 2023-07-04 | 352 | P07099 | Espacenet |
| JP 2023049296 A | 2023-04-10 | 31 | P07099 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 27810 | P07099 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 27811 | P07099 | Espacenet |
1 to 10 of 151
See all 151 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,407
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | EPHX1 papers | Newest fiscal year |
|---|---|---|---|
| R35ES030443 | Bioactive lipids as effectors and indicators of the deleterious effects of environmental exposure on chronic diseases | 15 | 2025 |
| P30ES007033 | University of Washington Interdisciplinary Center for Exposures, Diseases, Genomics & Environment | 11 | 2025 |
| P30ES010126 | UNC Center for Environmental Health and Susceptibility | 11 | 2025 |
| P30ES007048 | Environmental Exposures, Host Factors and Human Disease | 10 | 2025 |
| ZIAES025034 | Characterization And Functional Significance Of P450 Arachidonate Epoxygenases | 8 | 2025 |
| T32HL007427 | SYSTEMS APPROACHES TO THE EPIDEMIOLOGY, GENETICS AND GENOMICS OF LUNG DISEASES | 7 | 2025 |
| P30ES005605 | Environmental Health Sciences Research Center | 6 | 2025 |
| ZIACP010121 | Molecular Epidemiology Studies of Occupational and Environmental Exposures | 5 | 2025 |
| P30CA014089 | University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG) | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
1 to 10 of 1,407Source NIH's project files
See all 1,407 nih grantsPapers2,230
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Integrative multi-omics analyses suggest a candidate microbial metabolite-associated host gene network in ulcerative colitis. | Immunol Res | 2026 | 42696087 | PubTator, text mining | PubMed |
| Transcriptomic Analysis Reveals Core Genes and Mechanisms Linking Grilled Food Toxicants (4-HNE, BaP, PhIP) to NASH-HCC Progression. | Food Sci Nutr | 2026 | 42682783 | PubTator, text mining | PubMed |
| Environmental risk and genetic susceptibility in Alzheimer's disease: Impacts on cognitive function and biomarkers. | J Alzheimers Dis | 2026 | 42179068 | PubTator, text mining | PubMed |
| Epoxide Hydrolase Family: Biological Functions, Disease Mechanisms, and Emerging Therapeutic Strategies. | Biology (Basel) | 2026 | 42117830 | PubTator, text mining | PubMed |
| Genetic basis of phytoalexin-mediated chemical defense in plants. | Cell | 2026 | 42105761 | PubTator, text mining | PubMed |
| Clinically confirmed cohort reveals antioxidant genetic polymorphisms as potential susceptibility factors for long COVID after mild or asymptomatic COVID-19. | Free Radic Biol Med | 2026 | 41903617 | PubTator, text mining | PubMed |
| Integrated Bioinformatics Analysis Reveals the Impact of SHEV ORF3-Related LncRNA Network on Bile Secretion Pathway (ko 04976) in HepG2 Cells. | Vet Sci | 2026 | 41893693 | PubTator, text mining | PubMed |
| Limonin induces ferroptosis in cervical squamous cell carcinoma by activating the expression of soluble epoxide hydrolase 2 protein. | PLoS One | 2026 | 41838669 | PubTator, text mining | PubMed |
| Advancing the bioassay ontology through integrated PK/PD and safety pharmacology representation. | J Biomed Semantics | 2026 | 41821121 | PubTator, text mining | PubMed |
| Phosphorylations of serines 21/9 in glycogen synthase kinase 3α/β are dispensable for V600EBRAF-driven premalignant tumour development in the mouse intestine. | PLoS One | 2026 | 41790744 | PubTator, text mining | PubMed |
1 to 10 of 2,230
See all 2,230 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2052
GET https://conductscience.org/api/genes/v1/2052/patents?page=2