ConductScience.org, home

Gene · 2054

STX2: syntaxin 2

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. STX2: syntaxin 2. Genes, record 2054. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2054

On this page

Gene

Symbol
STX2
HGNC
Name
syntaxin 2
HGNC
NCBI Gene ID
2054
NCBI Gene
HGNC ID
HGNC:3403
HGNC
Ensembl
ENSG00000111450
NCBI Gene
Aliases
EPIM, EPM, STX2A, STX2B, STX2C
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P32856Syntaxin-22880Ensembl, GeneID, HGNC

Source UniProt

Patents28

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1466244P32856Espacenet
EP 4650780 A22025-11-1910915P32856Espacenet
JP 2025529142 A2025-09-044508P32856Espacenet
US 12371689 B22025-07-294508P32856Espacenet
JP 2025517970 A2025-06-1210915P32856Espacenet
US 11446398 B22022-09-2086019P32856Espacenet
US 11400116 B22022-08-026721P32856Espacenet
JP 2022524081 A2022-04-27188990P32856Espacenet
WO 2020043864 A12020-03-052506P32856Espacenet
JP 2019054813 A2019-04-11246679P32856Espacenet

1 to 10 of 28

See all 28 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants667

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSTX2 papersNewest fiscal year
P30DK052574Host-environment interactions in the pathophysiology of digestive disease102025
P30DK063491Diabetes Research Center (DRC)52025
P30DK034854Integrated Epithelial and Muscosal Biology32025
R01AI042347Host-pathogen interactions in experimental cholera32025
UL1TR001881UCLA Clinical and Translational Science Institute32025
ZIAHL006170Cardiovascular Genomics and Bioinformatics projects32025
P30CA008748Cancer Center Support Grant22025
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease22025
P40OD010440Caenorhabditis Genetics Center22025
R01NS017950Precursors of Stroke Incidence and Prognosis22025

1 to 10 of 667Source NIH's project files

See all 667 nih grants

Papers1,963

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Distinct mechanism of syntaxin3-dependent tight junction assembly in keratinocyte model cells.Cell Tissue Res202642776299PubTator, text miningPubMed
The antibiotic NAB815 does not induce SOS response and toxin production in Shiga toxin-producing Escherichia coli at sub-bactericidal concentrations.Int J Med Microbiol202642731261PubTator, text miningPubMed
Subtype-specific secretion of extracellular vesicles by LRRK2 and Rab GTPases under lysosomal stress.iScience202642630748PubTator, text miningPubMed
Susceptibility of Human B-Lymphoblastoid Cells to Shiga Toxin Intoxication Homologues.Microorganisms202642514010PubTator, text miningPubMed
PdIr bimetallic nanozyme engineered metal-organic frameworks integrated dual-mode sensor toward Stx2 detection in food.Food Chem202642431042PubTator, text miningPubMed
Prevalence, virulence profiles and antibiotic susceptibility patterns of Shiga toxin producing Escherichia coli O157:H7 among children 6-59 months in Longido, Arusha-Tanzania.PLoS One202642430368PubTator, text miningPubMed
Genetic susceptibility to obesity-related asthma and its modulation by sequelae of obesity.bioRxiv202642395418PubTator, text miningPubMed
Recombinant Human Fab Antibodies Differentially Neutralize Shiga Toxin in Renal Epithelial and Endothelial Cells.Toxins (Basel)202642347511PubTator, text miningPubMed
Locus of Adhesion and Autoaggregation (LAA) pathogenicity island genes hes and sisA are involved in virulence and biofilm formation in LEE-negative Shiga toxin-producing Escherichia coli (STEC).Microbiol Spectr202642294700PubTator, text miningPubMed
Association between air pollution exposure and increased chronic kidney disease risk: the modifying effects of genetic susceptibility, transcriptomic, and proteomic signatures.BMC Med202642106700PubTator, text miningPubMed

1 to 10 of 1,963

See all 1,963 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2054

GET https://conductscience.org/api/genes/v1/2054/patents?page=2