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Gene · 2057

EPOR: erythropoietin receptor

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. EPOR: erythropoietin receptor. Genes, record 2057. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2057

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Gene

Symbol
EPOR
HGNC
Name
erythropoietin receptor
HGNC
NCBI Gene ID
2057
NCBI Gene
HGNC ID
HGNC:3416
HGNC
Ensembl
ENSG00000187266
NCBI Gene
Aliases
EPO-R
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P19235Erythropoietin receptor50822Ensembl, GeneID, HGNC

Source UniProt

Patents126

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4705273 A22026-03-11312P19235Espacenet
JP 2026004568 A2026-01-1445270P19235Espacenet
JP 2025540009 A2025-12-1129P19235Espacenet
EP 4650780 A22025-11-19537P19235Espacenet
EP 4641201 A22025-10-29380P19235Espacenet
EP 4633648 A12025-10-2245P19235Espacenet
JP 2025147176 A2025-10-0616718P19235Espacenet
EP 4619440 A12025-09-2429P19235Espacenet
JP 2025529142 A2025-09-041425P19235Espacenet
US 12371689 B22025-07-291425P19235Espacenet

1 to 10 of 126

See all 126 patents

Drugs11

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
CIBINETIDECHEMBL3545305Innate repair receptor agonistAGONISTChEMBL
DARBEPOETIN ALFACHEMBL1201566Erythropoietin receptor agonistAGONISTChEMBL
EFEPOETIN ALFACHEMBL4594471Erythropoietin receptor agonistAGONISTChEMBL
EPOETIN ALFACHEMBL1201565Erythropoietin receptor agonistAGONISTChEMBL
EPOETIN BETACHEMBL2109092Erythropoietin receptor agonistAGONISTChEMBL
EPOETIN DELTACHEMBL2109093Erythropoietin receptor agonistAGONISTChEMBL
EPOETIN THETACHEMBL2108290Erythropoietin receptor agonistAGONISTChEMBL
EPOETIN ZETACHEMBL2108593Erythropoietin receptor agonistAGONISTChEMBL
METHOXY POLYETHYLENE GLYCOL-EPOETIN BETACHEMBL3707314Erythropoietin receptor agonistAGONISTChEMBL
PEGINESATIDECHEMBL2107866Erythropoietin receptor agonistAGONISTChEMBL

1 to 10 of 11

See all 11 drugs

Trials750

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07565701EPOETIN ALFAPHASE3ClinicalTrials.gov
NCT07463820EPOETIN ALFAPHASE2ClinicalTrials.gov
NCT07296146EPOETIN ALFAPHASE3ClinicalTrials.gov
NCT07296146DARBEPOETIN ALFAPHASE3ClinicalTrials.gov
NCT07296146EPOETIN BETAPHASE3ClinicalTrials.gov
NCT07258043EPOETIN BETAClinicalTrials.gov
NCT07131280DARBEPOETIN ALFAClinicalTrials.gov
NCT07119372EPOETIN BETAPHASE3ClinicalTrials.gov
NCT07096297DARBEPOETIN ALFAPHASE2ClinicalTrials.gov
NCT07045155EPOETIN ALFAPHASE4ClinicalTrials.gov

1 to 10 of 750

See all 750 trials

NIH grants1,855

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleEPOR papersNewest fiscal year
P30CA021765Cancer Center Support Grant (CCSG)352025
P01CA108671Myeloproliferative Neoplasms-Research Consortium252025
P30CA008748Cancer Center Support Grant252025
P30CA016672Cancer Center Support Grant232025
ZIADK025061Receptor Mediated Erythropoietin Metabolic Response152025
R01HL089966Erythropoietin receptor signaling in stress erythropoiesis and erythrocytosis112025
P30CA016058Cancer Center Support Grant102025
T32GM008721Molecular Biology in Burns and Trauma102025
R35CA197695Translating genomic discoveries to improved outcomes for high risk acute leukemia92025
T32CA128583Research Training in Childhood Cancer82025

1 to 10 of 1,855Source NIH's project files

See all 1,855 nih grants

Papers3,982

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Activation of the EPO-EPOR axis enhances dopamine agonist sensitivity through mitochondrial STAT5A-mediated suppression of mtDNA transcription in prolactinomas.Pharmacol Res202642822553PubTator, text miningPubMed
Unexpected functional role of the transactivation domain for nuclear import of STAT5.Commun Biol202642800796PubTator, text miningPubMed
Erythropoietin in Tumor Immunity: Mechanistic Evidence, Clinical Cautions, and Translational Opportunities.Cancers (Basel)202642794978PubTator, text miningPubMed
Association of Serum 1,25-Dihydroxyvitamin D Levels with Erythropoietin Resistance Index-Based Relative Erythropoiesis-Stimulating Agent Hyporesponsiveness in Pre-Dialysis Chronic Kidney Disease.Int J Mol Sci202642794474PubTator, text miningPubMed
Role of hypoxia-inducible factor - 1 alpha on the progression of cervical intraepithelial neoplasia and cervical cancer: a narrative review.Front Oncol202642787653PubTator, text miningPubMed
In vivo HSPC gene therapy of hemoglobinopathies without drug selection of corrected cells.bioRxiv202642779985PubTator, text miningPubMed
Erythropoietin impacts immune adaptation through myeloid-cell programming.Trends Immunol202642749579PubTator, text miningPubMed
Author Correction: Erythropoietin receptor on cDC1s dictates immune tolerance.Nature202642744852PubTator, text miningPubMed
Flow Cytometric Detection of Intracellular Proteins in K562 Human Erythroleukemia Cells Using Unconjugated Primary Antibodies.J Vis Exp202642714009PubTator, text miningPubMed
Integrated microbial and transcriptomic profiling reveals distinct correlations in atrophic gastritis associated with liver cirrhosis.Front Cell Infect Microbiol202642698600PubTator, text miningPubMed

1 to 10 of 3,982

See all 3,982 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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