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Gene · 2060

EPS15: epidermal growth factor receptor pathway substrate 15

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. EPS15: epidermal growth factor receptor pathway substrate 15. Genes, record 2060. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2060

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Gene

Symbol
EPS15
HGNC
Name
epidermal growth factor receptor pathway substrate 15
HGNC
NCBI Gene ID
2060
NCBI Gene
HGNC ID
HGNC:3419
HGNC
Ensembl
ENSG00000085832
NCBI Gene
Aliases
AF-1P, AF1P, MLLT5
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P42566Epidermal growth factor receptor substrate 1589613Ensembl, GeneID, HGNC

Source UniProt

Patents34

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1445104P42566Espacenet
EP 4650780 A22025-11-199004P42566Espacenet
EP 4641201 A22025-10-299243P42566Espacenet
JP 2025147176 A2025-10-064841P42566Espacenet
JP 2025529142 A2025-09-046282P42566Espacenet
US 12371689 B22025-07-296282P42566Espacenet
JP 2025517969 A2025-06-129243P42566Espacenet
JP 2025517970 A2025-06-129004P42566Espacenet
JP 2025032204 A2025-03-1127898P42566Espacenet
JP 2025028160 A2025-02-284841P42566Espacenet

1 to 10 of 34

See all 34 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,111

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleEPS15 papersNewest fiscal year
R35GM139531Protein Networks as Synergistic Drivers of Membrane Remodeling92025
R01GM072631Mechanisms of Gap Junction Regulation82025
P30CA008748Cancer Center Support Grant62025
ZIAHD001607Protein Trafficking In The Endosomal-Lysosomal System52025
ZIAHL006098Architecture and control of exocytosis and endocytosis in excitable cells52025
P30CA036727Buffett Cancer Center Support Grant42025
P30CA016672Cancer Center Support Grant32025
P30DK063491Diabetes Research Center (DRC)32025
R01CA096512Cell model for KSHV infection and genetic manipulation32025
R01CA124332Regulation of KSHV replication by N6-methyladenosine (m6A)32025

1 to 10 of 1,111Source NIH's project files

See all 1,111 nih grants

Papers1,477

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
The absorption and endocytosis mechanism of flaxseed cyclic peptide CLQ is mediated by its binding to clathrin.Food Res Int202642632707PubTator, text miningPubMed
Annexin A2 facilitates Japanese encephalitis virus replication by regulating endocytosis and intracellular transport in PK15 cells.Front Microbiol202642630443PubTator, text miningPubMed
Endocytic accessory proteins assemble clathrin while simultaneously destabilizing protein condensates.bioRxiv202642094558PubTator, text miningPubMed
Expression Analysis of miRNA Profiles in Colorectal Cancer with a Bioinformatics Approach: An Emphasis on miR-4295, miR-4720-5p, miR-4773, and miR-6831-5p.Diagnostics (Basel)202641750762PubTator, text miningPubMed
Intra-subtype heterogeneity shapes treatment response in KMT2A-rearranged ALL across all age groups.Hemasphere202641743263PubTator, text miningPubMed
Poly-ubiquitylated transmembrane proteins outcompete other cargo for limited space inside clathrin-coated vesicles.Cell Rep202541201087PubTator, text miningPubMed
Deciphering splicing heterogeneity at single-cell resolution by SCSES.Nat Commun202541145486PubTator, text miningPubMed
Extracellular vesicles: cargo loading, degradation and secretory pathways, and their intersection with autophagy.Extracell Vesicles Circ Nucl Acids202541132500PubTator, text miningPubMed
Of condensates and coats - reciprocal regulation of clathrin assembly and the growth of protein networks.Nat Commun202541093888PubTator, text miningPubMed
Novel insights into the relationship between glaucoma and brain diseases from the genetic to diseases levels: A cross-sectional study.Medicine (Baltimore)202540988281PubTator, text miningPubMed

1 to 10 of 1,477

See all 1,477 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2060

GET https://conductscience.org/api/genes/v1/2060/patents?page=2