Gene · 2060
EPS15: epidermal growth factor receptor pathway substrate 15
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. EPS15: epidermal growth factor receptor pathway substrate 15. Genes, record 2060. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2060
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P42566 | Epidermal growth factor receptor substrate 15 | 896 | 13 | Ensembl, GeneID, HGNC |
Source UniProt
Patents34
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 45104 | P42566 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 9004 | P42566 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 9243 | P42566 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 4841 | P42566 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6282 | P42566 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6282 | P42566 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 9243 | P42566 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 9004 | P42566 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 27898 | P42566 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 4841 | P42566 | Espacenet |
1 to 10 of 34
See all 34 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,111
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | EPS15 papers | Newest fiscal year |
|---|---|---|---|
| R35GM139531 | Protein Networks as Synergistic Drivers of Membrane Remodeling | 9 | 2025 |
| R01GM072631 | Mechanisms of Gap Junction Regulation | 8 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| ZIAHD001607 | Protein Trafficking In The Endosomal-Lysosomal System | 5 | 2025 |
| ZIAHL006098 | Architecture and control of exocytosis and endocytosis in excitable cells | 5 | 2025 |
| P30CA036727 | Buffett Cancer Center Support Grant | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 3 | 2025 |
| R01CA096512 | Cell model for KSHV infection and genetic manipulation | 3 | 2025 |
| R01CA124332 | Regulation of KSHV replication by N6-methyladenosine (m6A) | 3 | 2025 |
1 to 10 of 1,111Source NIH's project files
See all 1,111 nih grantsPapers1,477
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| The absorption and endocytosis mechanism of flaxseed cyclic peptide CLQ is mediated by its binding to clathrin. | Food Res Int | 2026 | 42632707 | PubTator, text mining | PubMed |
| Annexin A2 facilitates Japanese encephalitis virus replication by regulating endocytosis and intracellular transport in PK15 cells. | Front Microbiol | 2026 | 42630443 | PubTator, text mining | PubMed |
| Endocytic accessory proteins assemble clathrin while simultaneously destabilizing protein condensates. | bioRxiv | 2026 | 42094558 | PubTator, text mining | PubMed |
| Expression Analysis of miRNA Profiles in Colorectal Cancer with a Bioinformatics Approach: An Emphasis on miR-4295, miR-4720-5p, miR-4773, and miR-6831-5p. | Diagnostics (Basel) | 2026 | 41750762 | PubTator, text mining | PubMed |
| Intra-subtype heterogeneity shapes treatment response in KMT2A-rearranged ALL across all age groups. | Hemasphere | 2026 | 41743263 | PubTator, text mining | PubMed |
| Poly-ubiquitylated transmembrane proteins outcompete other cargo for limited space inside clathrin-coated vesicles. | Cell Rep | 2025 | 41201087 | PubTator, text mining | PubMed |
| Deciphering splicing heterogeneity at single-cell resolution by SCSES. | Nat Commun | 2025 | 41145486 | PubTator, text mining | PubMed |
| Extracellular vesicles: cargo loading, degradation and secretory pathways, and their intersection with autophagy. | Extracell Vesicles Circ Nucl Acids | 2025 | 41132500 | PubTator, text mining | PubMed |
| Of condensates and coats - reciprocal regulation of clathrin assembly and the growth of protein networks. | Nat Commun | 2025 | 41093888 | PubTator, text mining | PubMed |
| Novel insights into the relationship between glaucoma and brain diseases from the genetic to diseases levels: A cross-sectional study. | Medicine (Baltimore) | 2025 | 40988281 | PubTator, text mining | PubMed |
1 to 10 of 1,477
See all 1,477 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2060
GET https://conductscience.org/api/genes/v1/2060/patents?page=2