Gene · 21
ABCA3: ATP binding cassette subfamily A member 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ABCA3: ATP binding cassette subfamily A member 3. Genes, record 21. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/21
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q99758 | Phospholipid-transporting ATPase ABCA3 | 1,704 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents25
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026509256 A | 2026-03-17 | 61 | Q99758 | Espacenet |
| JP 2026027383 A | 2026-02-18 | 25 | Q99758 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 38362 | Q99758 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 3654 | Q99758 | Espacenet |
| JP 2025533754 A | 2025-10-09 | 26 | Q99758 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 180 | Q99758 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 180 | Q99758 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 3654 | Q99758 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 7597 | Q99758 | Espacenet |
| JP 2024028256 A | 2024-03-04 | 5 | Q99758 | Espacenet |
1 to 10 of 25
See all 25 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants938
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ABCA3 papers | Newest fiscal year |
|---|---|---|---|
| R01HL149853 | Functional Characterization of ABCA3 Genomic Variants | 12 | 2025 |
| R01HL095993 | Derivation of lung epithelia from iPS cells for advanced disease modeling | 8 | 2025 |
| P30ES013508 | Center of Excellence in Environmental Toxicology | 7 | 2025 |
| ZIABC010830 | Mechanisms of non-classical multidrug resistance in cancer | 6 | 2025 |
| P30CA014089 | University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG) | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| T32DE007057 | Tissue Engineering and Regeneration | 4 | 2025 |
| ZIABC005598 | Genetic Analysis of the Multidrug Resistance Phenotype in Tumor Cells | 4 | 2025 |
| ZIABC010030 | Biochemical Analysis of Multidrug Resistance-linked Transport Proteins | 4 | 2025 |
| P30DK054759 | Precision Medicine Center for Cystic Fibrosis | 3 | 2025 |
1 to 10 of 938Source NIH's project files
See all 938 nih grantsPapers1,534
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Adulthood interstitial lung disease due to variants in surfactant related genes: A systematic review. | Pulmonology | 2026 | 42784242 | PubTator, text mining | PubMed |
| Masked ABCA3-Related Interstitial Lung Disease in a Neonate With Prenatally Diagnosed Total Anomalous Pulmonary Venous Connection. | J Clin Ultrasound | 2026 | 42693532 | PubTator, text mining | PubMed |
| The Value of Lung Biopsy in Infants up to 3 Months With Diffuse Lung Disease in a Resource-Limited Setting. | Can Respir J | 2026 | 42678672 | PubTator, text mining | PubMed |
| Intratumoral Corynebacterium is associated with phospholipid metabolic reprogramming and spread through air spaces in lung adenocarcinoma. | Front Cell Infect Microbiol | 2026 | 42620632 | PubTator, text mining | PubMed |
| Interstitial Lung Disease in Children: Rare Genetic Variants Beyond Surfactant Dysfunction. | Pediatr Pulmonol | 2026 | 42598967 | PubTator, text mining | PubMed |
| DNA Methylation of Pharmacologic and Leukemia-Related Genes Predicts Clinical Outcomes in Pediatric Acute Myeloid Leukemia. | Cancers (Basel) | 2026 | 42588684 | PubTator, text mining | PubMed |
| Respiratory Outcomes in Children With Neonatal Respiratory Distress Syndrome and Monoallelic ABCA3 Variants. | Pediatr Pulmonol | 2026 | 42295024 | PubTator, text mining | PubMed |
| The Hidden Variant: Intronic ABCA3 Mutation in Lethal Neonatal Interstitial Lung Disease. | Pediatr Pulmonol | 2026 | 42295001 | PubTator, text mining | PubMed |
| Lentiviral-mediated gene complementation to rescue pathogenic ABCA3 variants. | Am J Respir Cell Mol Biol | 2026 | 42089300 | PubTator, text mining | PubMed |
| Long-Term Static Cultivation Alters Lipid Metabolism and Bioenergetic Capacity in A549 Cells. | Int J Mol Sci | 2026 | 42074059 | PubTator, text mining | PubMed |
1 to 10 of 1,534
See all 1,534 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/21
GET https://conductscience.org/api/genes/v1/21/patents?page=2