Gene · 210
ALAD: aminolevulinate dehydratase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ALAD: aminolevulinate dehydratase. Genes, record 210. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/210
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P13716 | Delta-aminolevulinic acid dehydratase | 330 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents28
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026067851 A | 2026-04-21 | 100 | P13716 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 37229 | P13716 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 12017 | P13716 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 12017 | P13716 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 4435 | P13716 | Espacenet |
| JP 2023521663 A | 2023-05-25 | 99 | P13716 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 4435 | P13716 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 107406 | P13716 | Espacenet |
| JP 2021530985 A | 2021-11-18 | 207 | P13716 | Espacenet |
| WO 2021202604 A1 | 2021-10-07 | 100 | P13716 | Espacenet |
1 to 10 of 28
See all 28 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants704
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ALAD papers | Newest fiscal year |
|---|---|---|---|
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 44 | 2025 |
| U54DK110858 | Center for Iron & Heme Disorders at the University of Utah | 8 | 2025 |
| R01ES010563 | Mechanisms of Manganese Neurotoxicity | 7 | 2025 |
| R01ES007331 | Mechanisms of Methylmercury Induced Neuronal Toxicity | 6 | 2025 |
| P30ES017885 | Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD) | 4 | 2025 |
| R01DK074797 | Inter-organ signaling in heme metabolism and organismal homeostasis. | 4 | 2025 |
| R01ES013744 | Stress-Air Pollution Interactions and Adolescent Neurobehavior | 4 | 2025 |
| ZIACP010121 | Molecular Epidemiology Studies of Occupational and Environmental Exposures | 4 | 2025 |
| T32ES007126 | Pre- and Postdoctoral Training in Toxicology | 3 | 2025 |
| T42OH008416 | Harvard TH Chan Education and Research Center for Occupational Safety and Health | 3 | 2025 |
1 to 10 of 704Source NIH's project files
See all 704 nih grantsPapers2,933
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| An Investigation to Study Morphology, Nanomechanical Attributes, Transcriptomics, and Proteomics of Tumor Associated Macrophages Derived Extracellular Vesicles in the Tumor Microenvironment. | J Anal Oncol | 2026 | 42719843 | PubTator, text mining | PubMed |
| Transcriptomic and predictive modeling reveal photosynthetic and stress responses associated with ALAD silencing in citrus. | Planta | 2026 | 42704501 | PubTator, text mining | PubMed |
| Glycine improves boar sperm linear motility by promoting heme biosynthesis to regulate mitochondrial energy metabolism. | Theriogenology | 2026 | 42667783 | PubTator, text mining | PubMed |
| From Environmental Lead Exposure to Colorectal Cancer: Integrated Transcriptomic and Genetic Analyses Identify HMOX1 as a Prioritized Candidate. | Biol Trace Elem Res | 2026 | 42560444 | PubTator, text mining | PubMed |
| Identification of Bone Marrow and Peripheral Blood Plasma Extracellular Vesicle Protein Biomarker Signatures for Multiple Myeloma Diagnosis and Staging. | Int J Nanomedicine | 2026 | 42371508 | PubTator, text mining | PubMed |
| In-Depth Plasma Proteomics Identifies SNCA as a Discriminating Biomarker of PDAC. | J Proteome Res | 2026 | 42223356 | PubTator, text mining | PubMed |
| Iron-addicted colorectal cancers exploit heme-complex II axis to resist oxidative cell death. | Cell Metab | 2026 | 42202783 | PubTator, text mining | PubMed |
| Somatic mosaicism in the δ-aminolevulinate dehydratase gene causing late-onset porphyria with erythroid-driven pathogenesis. | Mol Genet Metab Rep | 2026 | 42158594 | PubTator, text mining | PubMed |
| Integrated multi-omics data and machine learning approaches to decipher the molecular network and gene signatures of renal cell carcinoma induced by aristolochic acid. | Biochem Biophys Res Commun | 2026 | 42033937 | PubTator, text mining | PubMed |
| Prognostic value of fatty acid metabolism-related genes in colorectal cancer. | Int J Clin Exp Pathol | 2026 | 42005274 | PubTator, text mining | PubMed |
1 to 10 of 2,933
See all 2,933 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/210
GET https://conductscience.org/api/genes/v1/210/patents?page=2