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Gene · 210

ALAD: aminolevulinate dehydratase

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ALAD: aminolevulinate dehydratase. Genes, record 210. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/210

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Gene

Symbol
ALAD
HGNC
Name
aminolevulinate dehydratase
HGNC
NCBI Gene ID
210
NCBI Gene
HGNC ID
HGNC:395
HGNC
Ensembl
ENSG00000148218
NCBI Gene
Aliases
ALADH, PBGS
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P13716Delta-aminolevulinic acid dehydratase3304Ensembl, GeneID, HGNC

Source UniProt

Patents28

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026067851 A2026-04-21100P13716Espacenet
JP 2026004568 A2026-01-1437229P13716Espacenet
EP 4650780 A22025-11-1912017P13716Espacenet
JP 2025517970 A2025-06-1212017P13716Espacenet
JP 2025062604 A2025-04-144435P13716Espacenet
JP 2023521663 A2023-05-2599P13716Espacenet
US 11446398 B22022-09-204435P13716Espacenet
JP 2022524081 A2022-04-27107406P13716Espacenet
JP 2021530985 A2021-11-18207P13716Espacenet
WO 2021202604 A12021-10-07100P13716Espacenet

1 to 10 of 28

See all 28 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants704

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleALAD papersNewest fiscal year
P30CA006927Comprehensive Cancer Center Program at Fox Chase442025
U54DK110858Center for Iron & Heme Disorders at the University of Utah82025
R01ES010563Mechanisms of Manganese Neurotoxicity72025
R01ES007331Mechanisms of Methylmercury Induced Neuronal Toxicity62025
P30ES017885Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD)42025
R01DK074797Inter-organ signaling in heme metabolism and organismal homeostasis.42025
R01ES013744Stress-Air Pollution Interactions and Adolescent Neurobehavior42025
ZIACP010121Molecular Epidemiology Studies of Occupational and Environmental Exposures42025
T32ES007126Pre- and Postdoctoral Training in Toxicology32025
T42OH008416Harvard TH Chan Education and Research Center for Occupational Safety and Health32025

1 to 10 of 704Source NIH's project files

See all 704 nih grants

Papers2,933

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
An Investigation to Study Morphology, Nanomechanical Attributes, Transcriptomics, and Proteomics of Tumor Associated Macrophages Derived Extracellular Vesicles in the Tumor Microenvironment.J Anal Oncol202642719843PubTator, text miningPubMed
Transcriptomic and predictive modeling reveal photosynthetic and stress responses associated with ALAD silencing in citrus.Planta202642704501PubTator, text miningPubMed
Glycine improves boar sperm linear motility by promoting heme biosynthesis to regulate mitochondrial energy metabolism.Theriogenology202642667783PubTator, text miningPubMed
From Environmental Lead Exposure to Colorectal Cancer: Integrated Transcriptomic and Genetic Analyses Identify HMOX1 as a Prioritized Candidate.Biol Trace Elem Res202642560444PubTator, text miningPubMed
Identification of Bone Marrow and Peripheral Blood Plasma Extracellular Vesicle Protein Biomarker Signatures for Multiple Myeloma Diagnosis and Staging.Int J Nanomedicine202642371508PubTator, text miningPubMed
In-Depth Plasma Proteomics Identifies SNCA as a Discriminating Biomarker of PDAC.J Proteome Res202642223356PubTator, text miningPubMed
Iron-addicted colorectal cancers exploit heme-complex II axis to resist oxidative cell death.Cell Metab202642202783PubTator, text miningPubMed
Somatic mosaicism in the δ-aminolevulinate dehydratase gene causing late-onset porphyria with erythroid-driven pathogenesis.Mol Genet Metab Rep202642158594PubTator, text miningPubMed
Integrated multi-omics data and machine learning approaches to decipher the molecular network and gene signatures of renal cell carcinoma induced by aristolochic acid.Biochem Biophys Res Commun202642033937PubTator, text miningPubMed
Prognostic value of fatty acid metabolism-related genes in colorectal cancer.Int J Clin Exp Pathol202642005274PubTator, text miningPubMed

1 to 10 of 2,933

See all 2,933 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/210

GET https://conductscience.org/api/genes/v1/210/patents?page=2