Gene · 2101
ESRRA: estrogen related receptor alpha
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ESRRA: estrogen related receptor alpha. Genes, record 2101. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2101
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P11474 | Steroid hormone receptor ERR1 | 423 | 6 | Ensembl, GeneID, HGNC |
Source UniProt
Patents36
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 45287 | P11474 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 45288 | P11474 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 14943 | P11474 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 14943 | P11474 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 14943 | P11474 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 14782 | P11474 | Espacenet |
| US 11981931 B2 | 2024-05-14 | 11 | P11474 | Espacenet |
| JP 2024519218 A | 2024-05-09 | 113 | P11474 | Espacenet |
| KR 1020240005837 A | 2024-01-12 | 70 | P11474 | Espacenet |
| US 11583555 B2 | 2023-02-21 | 2 | P11474 | Espacenet |
1 to 10 of 36
See all 36 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,658
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ESRRA papers | Newest fiscal year |
|---|---|---|---|
| P20GM103427 | Nebraska Research Network in Functional Genomics | 10 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| P30CA051008 | Georgetown University Lombardi Comprehensive Cancer Center Support Grant | 7 | 2025 |
| R35CA197589 | Inducing Proximity: An Emerging Paradigm for New Therapeutic Modalities | 7 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 6 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 6 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 6 | 2025 |
| P30DK056341 | Washington University Nutrition Obesity Research Center | 6 | 2025 |
| R01DK076077 | Adaptive and maladaptive repair after kidney injury | 6 | 2025 |
| P01CA022443 | Molecular Biology and Genetics of Human Tumor Viruses | 5 | 2025 |
1 to 10 of 1,658Source NIH's project files
See all 1,658 nih grantsPapers2,737
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Integrative transcriptomic and regulatory network analysis reveals associations of seven proposed risk genes with immune-related molecular features in Alzheimer's disease. | J Alzheimers Dis | 2026 | 42813688 | PubTator, text mining | PubMed |
| PGC1α-mediated upregulation of PHD2 represses HIF-signaling, limiting prostate cancer progression. | Cell Death Differ | 2026 | 42754649 | PubTator, text mining | PubMed |
NLR family pyrin domain containing 3-mediated Kupffer cell pyroptosis aggravates ischemia-reperfusion injury after aging donor liver transplantation through CD38-nicotinamide adenine dinucleotide+-sirtuin 1-dependent acetylation of estrogen-related receptor α. | Am J Transplant | 2026 | 42710596 | PubTator, text mining | PubMed |
| Role of estrogen-related receptor alpha in osteogenic differentiation. | Hum Cell | 2026 | 42704564 | PubTator, text mining | PubMed |
| Estrogen-related receptor α promotes breast cancer cell migration and invasion by activating transforming growth factor β signaling. | Anticancer Drugs | 2026 | 42669034 | PubTator, text mining | PubMed |
| USP16 promotes osteosarcoma progression by stabilizing ESRRA to enhance mitochondrial oxidative phosphorylation. | Biochem Biophys Res Commun | 2026 | 42659864 | PubTator, text mining | PubMed |
| Kaempferol's Therapeutic Applications and Mechanistic Insights in Ocular Diseases: Current Progress, Challenges, and Translational Opportunities. | Pharmaceutics | 2026 | 42654113 | PubTator, text mining | PubMed |
Recent Advances (2020-2025) in Estrogen and ER-Positive Breast Cancer: Receptor Signaling, Tumor Microenvironment, Endocrine Therapy Resistance and Innovative Treatment Strategies-A Comprehensive Review. | Cancer Manag Res | 2026 | 42634815 | PubTator, text mining | PubMed |
| ERRα ameliorates osteoarthritis by inhibiting chondrocyte pyroptosis via targeting NF-κBp65. | Eur J Pharmacol | 2026 | 42624454 | PubTator, text mining | PubMed |
| Female chronic social defeat stress (femCSDS) maps synaptic, bioenergetic and metabolic proteome remodeling in the nucleus accumbens (NAc). | Front Syst Biol | 2026 | 42614171 | PubTator, text mining | PubMed |
1 to 10 of 2,737
See all 2,737 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2101
GET https://conductscience.org/api/genes/v1/2101/patents?page=2