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Gene · 2114

ETS2: ETS proto-oncogene 2, transcription factor

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ETS2: ETS proto-oncogene 2, transcription factor. Genes, record 2114. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2114

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Gene

Symbol
ETS2
HGNC
Name
ETS proto-oncogene 2, transcription factor
HGNC
NCBI Gene ID
2114
NCBI Gene
HGNC ID
HGNC:3489
HGNC
Ensembl
ENSG00000157557
NCBI Gene
Aliases
ETS2IT1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P15036Protein C-ets-24692Ensembl, GeneID, HGNC

Source UniProt

Patents47

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-197753P15036Espacenet
JP 2025147176 A2025-10-0614948P15036Espacenet
JP 2025517970 A2025-06-127753P15036Espacenet
JP 2025028160 A2025-02-2814948P15036Espacenet
KR 1020250010750 A2025-01-2114948P15036Espacenet
WO 2024208705 A12024-10-104P15036Espacenet
JP 2024123008 A2024-09-108982P15036Espacenet
JP 2024123008 A2024-09-108983P15036Espacenet
JP 2024109657 A2024-08-1414787P15036Espacenet
JP 2024519218 A2024-05-09114P15036Espacenet

1 to 10 of 47

See all 47 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,885

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleETS2 papersNewest fiscal year
P30CA016672Cancer Center Support Grant212025
P30CA016058Cancer Center Support Grant112025
P30CA008748Cancer Center Support Grant102025
P30CA042014Cancer Center Support Grant92025
P30CA046934University of Colorado Cancer Center Support Grant52025
P30CA006973Regional Oncology Research Center42025
P30CA010815Consolidated Basic Cancer Research Program42025
P30CA016086Cancer Center Support Grant42025
P30CA030199Cancer Center Support Grant (CCSG)42025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant42025

1 to 10 of 1,885Source NIH's project files

See all 1,885 nih grants

Papers2,490

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
ETS-2 deficiency impairs brown adipose tissue function through Prdm16 repression.Metabolism202642800535PubTator, text miningPubMed
An Exploratory Single-Cell Analysis Identifies Candidate Shared Molecular Features in Proliferative Diabetic Retinopathy and Parkinson's Disease.Genes (Basel)202642792898PubTator, text miningPubMed
Integrated Structural and Dynamic Analysis Reveals Destabilizing Effects of KRAS Missense Variants Associated with Lung Cancer.Protein J202642791474PubTator, text miningPubMed
Corrigendum to: ΔNp73/ETS2 complex drives glioblastoma pathogenesis-targeting downstream mediators by rebastinib prolongs survival in preclinical models of glioblastoma.Neuro Oncol202642710498PubTator, text miningPubMed
STAT3-mediated suppression of the pre-induction silencer Ets-2 in activated T helper cells.Mol Biol Rep202642684610PubTator, text miningPubMed
Multi-Omic Analysis of Putative Cellular Senescence-Associated Genes on the Risk of Pan-Cancer.Mol Carcinog202642669193PubTator, text miningPubMed
Magnolol triggers ferroptosis in triple-negative breast cancer through modulation of the ETS2/SLC7A11/GPX4 signaling axis.Front Pharmacol202642602283PubTator, text miningPubMed
Extracellular Vesicles in Cardiovascular Disease: Intercellular Signaling, Liquid Biopsy Biomarkers, and Therapeutic Translation.Circ Res202642594169PubTator, text miningPubMed
From proteome-wide Mendelian randomization and multi-omics integration to functional validation: TGFB3 as a prioritized candidate in gastric adenocarcinoma.Front Oncol202642518818PubTator, text miningPubMed
Is Cellular Senescence a Biological Feature of Long COVID? A Transcriptomic Analysis Across Comparative Postacute Sequelae Phenotypes.J Infect Dis202642340243PubTator, text miningPubMed

1 to 10 of 2,490

See all 2,490 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2114

GET https://conductscience.org/api/genes/v1/2114/patents?page=2