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Gene · 2115

ETV1: ETS variant transcription factor 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ETV1: ETS variant transcription factor 1. Genes, record 2115. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2115

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Gene

Symbol
ETV1
HGNC
Name
ETS variant transcription factor 1
HGNC
NCBI Gene ID
2115
NCBI Gene
HGNC ID
HGNC:3490
HGNC
Ensembl
ENSG00000006468
NCBI Gene
Aliases
ER81
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P50549ETS translocation variant 14773Ensembl, GeneID, HGNC

Source UniProt

Patents69

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4641201 A22025-10-2912773P50549Espacenet
JP 2025147176 A2025-10-0614949P50549Espacenet
JP 2025517969 A2025-06-1212773P50549Espacenet
JP 2025032204 A2025-03-1128016P50549Espacenet
JP 2025032204 A2025-03-1128020P50549Espacenet
JP 2025028160 A2025-02-2814949P50549Espacenet
KR 1020250010750 A2025-01-2114949P50549Espacenet
EP 4461818 A22024-11-1328016P50549Espacenet
EP 4461818 A22024-11-1328020P50549Espacenet
JP 2024123008 A2024-09-106060P50549Espacenet

1 to 10 of 69

See all 69 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,813

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleETV1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant542025
P30CA016672Cancer Center Support Grant232025
P50CA092629SPORE in Prostate Cancer172025
P50CA097186The Pacific Northwest Prostate Cancer SPORE172025
P30CA042014Cancer Center Support Grant162025
P50CA186786Michigan Prostate SPORE 2025-2030152025
U01CA113913Prostate Cancer Biomarker and Imaging Validation Alliance: Emory University, University of Alabama Birmingham, and University of Texas Southwestern142025
P30CA006973Regional Oncology Research Center112025
R01CA193837Role of ETS factors in specifying prostate luminal cell identity and androgen receptor dependence102025
P50CA217694SPORE in Soft Tissue Sarcoma92025

1 to 10 of 1,813Source NIH's project files

See all 1,813 nih grants

Papers2,342

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Postmitotic Regulation of Neuronal Subpopulations in the Cerebellum.bioRxiv202642798398PubTator, text miningPubMed
A molecularly anchored spatial transcriptomic framework for precise CA1-subiculum parcellation and region-resolved analysis in Alzheimer's disease.Gigascience202642752570PubTator, text miningPubMed
SHH mediated human dopaminergic neuron differentiation is facilitated by transcription factor ZIC3.Biochim Biophys Acta Mol Cell Res202642702224PubTator, text miningPubMed
scRNA-Seq Links CD8 Effector T Cells to Periodontitis via Transcriptional Reprogramming and Enhanced PARs Signaling.Oral Dis202642638197PubTator, text miningPubMed
ETV1/TGF-β/SMAD4-CTGF Axis Activated Tumor-CAFs Crosstalk Promotes Poor Progression in Hepatocellular Carcinoma Patients.Cancer Med202642629631PubTator, text miningPubMed
Mega-enhancers compartmentalize transcriptionally active long genes in the brain.Nat Cell Biol202642575995PubTator, text miningPubMed
Metabolic reprogramming drives pancreatic β cell neogenesis from α cells.Nat Chem Biol202642567976PubTator, text miningPubMed
Transcriptional regulation of the TASK-1 potassium channel by ETV1 - Implications for atrial excitability.J Mol Cell Cardiol202642532405PubTator, text miningPubMed
H3K18 lactylation drives CD8+ T cell exclusion and anti-PD-1 resistance in hepatocellular carcinoma.Cell Rep202642519827PubTator, text miningPubMed
In silico evaluation of the role of PEA3 subfamily ETS transcription factors in chemoresistance in ovarian cancer.Turk J Med Sci202642499433PubTator, text miningPubMed

1 to 10 of 2,342

See all 2,342 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2115

GET https://conductscience.org/api/genes/v1/2115/patents?page=2