Gene · 2118
ETV4: ETS variant transcription factor 4
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ETV4: ETS variant transcription factor 4. Genes, record 2118. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2118
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P43268 | ETS translocation variant 4 | 484 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents75
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2025147176 A | 2025-10-06 | 14953 | P43268 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 28033 | P43268 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 28034 | P43268 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 28037 | P43268 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 14953 | P43268 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 14953 | P43268 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 28033 | P43268 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 28034 | P43268 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 28037 | P43268 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 6068 | P43268 | Espacenet |
1 to 10 of 75
See all 75 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,841
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ETV4 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 47 | 2025 |
| P30CA042014 | Cancer Center Support Grant | 19 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 18 | 2025 |
| P50CA097186 | The Pacific Northwest Prostate Cancer SPORE | 15 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 10 | 2025 |
| P50CA092629 | SPORE in Prostate Cancer | 10 | 2025 |
| P50CA186786 | Michigan Prostate SPORE 2025-2030 | 10 | 2025 |
| R01HD008188 | Reproductive Hormones - Biological and Molecular Actions | 9 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 8 | 2025 |
| R01HD007857 | Sex Hormone Receptor Component And The Cell Genome | 8 | 2025 |
1 to 10 of 1,841Source NIH's project files
See all 1,841 nih grantsPapers2,714
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
Corrigendum to: "FGF19/FGFR4-mediated elevation of ETV4 facilitates hepatocellular carcinoma metastasis by upregulating PD-L1 and CCL2" [J Hepatol (2023) 79(1):109-125; DOI: 10.1016/j.jhep.2023.02.036]. | J Hepatol | 2026 | 42716826 | PubTator, text mining | PubMed |
| Single-cell mapping of tumor-driven macrophage reprogramming via ETV4-MC1R underlies immunotherapy resistance in colorectal cancer. | Int J Surg | 2026 | 42682293 | PubTator, text mining | PubMed |
| Epigenetic modulation of stromal cell states underpins pathological tissue niches in Crohn's disease. | Nat Immunol | 2026 | 42587037 | PubTator, text mining | PubMed |
| Synthesis of Biobased Aliphatic Poly(ester amide)s and Their Thermal, Tensile Properties, and Selective Depolymerization through Transesterification. | JACS Au | 2026 | 42529620 | PubTator, text mining | PubMed |
| Emerging role of ETV4 in colorectal cancer: from molecular mechanisms to clinical implications. | Front Oncol | 2026 | 42528596 | PubTator, text mining | PubMed |
| Systems Biology and Experimental Validation Enable Discovery of MMP9-Centered Networks, Anticancer Activity, and Pharmacodynamic Signature in Non-Small Cell Lung Cancer. | Int J Mol Sci | 2026 | 42511800 | PubTator, text mining | PubMed |
| In silico evaluation of the role of PEA3 subfamily ETS transcription factors in chemoresistance in ovarian cancer. | Turk J Med Sci | 2026 | 42499433 | PubTator, text mining | PubMed |
| Identification of genomic features that uniquely impact estrogen receptor alpha binding and its effects on gene expression in endometrial cancer. | Genome Res | 2026 | 42469015 | PubTator, text mining | PubMed |
| Transcription factors ETV4 and ETV5 are required for nephron progenitor cell maintenance, distal nephron development and connection to the collecting system. | Front Cell Dev Biol | 2026 | 42459831 | PubTator, text mining | PubMed |
| Identification of genomic features that uniquely impact estrogen receptor alpha binding and its effects on gene expression in endometrial cancer. | bioRxiv | 2026 | 42427750 | PubTator, text mining | PubMed |
1 to 10 of 2,714
See all 2,714 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2118
GET https://conductscience.org/api/genes/v1/2118/patents?page=2