Gene · 2131
EXT1: exostosin glycosyltransferase 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. EXT1: exostosin glycosyltransferase 1. Genes, record 2131. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2131
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q16394 | Exostosin-1 | 746 | 6 | Ensembl, GeneID, HGNC |
Source UniProt
Patents32
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4641201 A2 | 2025-10-29 | 10296 | Q16394 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1461 | Q16394 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1461 | Q16394 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 10296 | Q16394 | Espacenet |
| WO 2025093745 A1 | 2025-05-08 | 130 | Q16394 | Espacenet |
| US 12203933 B2 | 2025-01-21 | 2 | Q16394 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 6148 | Q16394 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 29174 | Q16394 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 37 | Q16394 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 132145 | Q16394 | Espacenet |
1 to 10 of 32
See all 32 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,014
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | EXT1 papers | Newest fiscal year |
|---|---|---|---|
| R01AR061758 | Pathogenic Mechanisms in Hereditary Multiple Exostoses Syndrome | 13 | 2025 |
| P30ES017885 | Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD) | 5 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| R35ES031686 | Environmental Epigenomics and Precision Environmental Health | 4 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 3 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 3 | 2025 |
| R01EY018868 | Integrating biomechanical and biochemical signaling in lacrimal gland development | 3 | 2025 |
| T32HG000040 | University of Michigan Training Program in Genomic Science | 3 | 2025 |
| U19AI135972 | SARS-CoV adaptations through a Systems Biology Lens (SYBIL) | 3 | 2025 |
1 to 10 of 1,014Source NIH's project files
See all 1,014 nih grantsPapers1,841
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Identification of a Lactylation-Related Gene Signature and Candidate Biomarkers for Dilated Cardiomyopathy. | J Cell Mol Med | 2026 | 42791204 | PubTator, text mining | PubMed |
| Tumor-associated osteoclasts converge on a matrix-sulfation program across human bone tumors. | Front Cell Dev Biol | 2026 | 42787358 | PubTator, text mining | PubMed |
| EXT1 in cardiomyocytes promotes heparan sulphate-dependent accumulation of macrophage-derived SOD2 to protect against post-myocardial infarction injury. | Br J Pharmacol | 2026 | 42764678 | PubTator, text mining | PubMed |
| Optical genome mapping identifies cryptic balanced chromosomal rearrangements in karyotypically normal couples with recurrent pregnancy loss or adverse pregnancy history. | Hum Mol Genet | 2026 | 42762433 | PubTator, text mining | PubMed |
| MPO-ANCA-associated glomerulonephritis with immune complex deposition and membranous features in a patient with Sjögren's syndrome: a case report. | CEN Case Rep | 2026 | 42645684 | PubTator, text mining | PubMed |
| Prenatal diagnosis of familial 8q24.11q24.12 and 8q24.13 microdeletions encompassing the exon 1 of EXT1 associated with no apparently phenotypic abnormality in the family carrier members. | Taiwan J Obstet Gynecol | 2026 | 42642131 | PubTator, text mining | PubMed |
| Role of EXT Family Enzymes in Heparan Sulfate Biosynthesis. | J Histochem Cytochem | 2026 | 42638461 | PubTator, text mining | PubMed |
| Evolutionary study of oncogenes and tumor suppressor genes in breast carcinoma. | J Taibah Univ Med Sci | 2026 | 42633313 | PubTator, text mining | PubMed |
| Corrigendum to "Deficiency of EXT1 and FGFR3 genes promotes chondrocyte differentiation, leading to the induction of osteochondroma formation" [Bone 192 (2025) 117370]. | Bone | 2026 | 42613289 | PubTator, text mining | PubMed |
| High-coverage paleo-genome research identifies a pathogenic mutation on EXT1 in a Qing-period Chinese individual with multiple osteochondromas. | Mol Genet Genomics | 2026 | 42501091 | PubTator, text mining | PubMed |
1 to 10 of 1,841
See all 1,841 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2131
GET https://conductscience.org/api/genes/v1/2131/patents?page=2