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Gene · 2175

FANCA: FA complementation group A

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FANCA: FA complementation group A. Genes, record 2175. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2175

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Gene

Symbol
FANCA
HGNC
Name
FA complementation group A
HGNC
NCBI Gene ID
2175
NCBI Gene
HGNC ID
HGNC:3582
HGNC
Ensembl
ENSG00000187741
NCBI Gene
Aliases
FA, FA-H, FA1, FAA, FACA, FAH, FANCH
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O15360Fanconi anemia group A protein1,4556Ensembl, GeneID, HGNC

Source UniProt

Patents28

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1910673O15360Espacenet
EP 4641201 A22025-10-2911072O15360Espacenet
JP 2025529142 A2025-09-041528O15360Espacenet
US 12371689 B22025-07-291528O15360Espacenet
JP 2025517969 A2025-06-1211072O15360Espacenet
JP 2025517970 A2025-06-1210673O15360Espacenet
JP 2025510777 A2025-04-151O15360Espacenet
JP 2024123008 A2024-09-106170O15360Espacenet
US 11976334 B22024-05-07145O15360Espacenet
US 11446398 B22022-09-2030631O15360Espacenet

1 to 10 of 28

See all 28 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,086

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFANCA papersNewest fiscal year
P30CA008748Cancer Center Support Grant712025
P30CA016672Cancer Center Support Grant342025
R01HL052725Molecular Pathogenesis of Fanconi Anemia342025
ZIACP010144Clinical Genetic Studies of Familial and Hereditary Cancer Syndromes192025
P30CA006973Regional Oncology Research Center172025
P30CA015704Cancer Center Support Grant142025
ZIAAG000688Investigate the DNA damage response pathway of Fanconi anemia and BRCA proteins132025
ZIAHG000029Fanconi Anemia: Genotype-Phenotype Correlations132025
ZIAAG000741Roles Of DNA Helicases In Pathways Required For Maintenance Of Genomic Stability122025
P50CA092629SPORE in Prostate Cancer112025

1 to 10 of 2,086Source NIH's project files

See all 2,086 nih grants

Papers3,803

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Evaluating interaction of pharmacologically potent organoselenides with transport protein human serum albumin: Spectroscopic and molecular dynamic simulations based mechanistic insights.Spectrochim Acta A Mol Biomol Spectrosc202742790013PubTator, text miningPubMed
Clinical, cytogenetic, and molecular insights from 32 years of the Portuguese Fanconi anemia cohort.Genet Med Open202642824411PubTator, text miningPubMed
FA1 site-targeted fluorescent probe for HSA detection and labeling: Biomedical applications and MD insights into local conformational perturbation.Bioorg Chem202642772097PubTator, text miningPubMed
Integrative proteomics defines FANCA as a multifunctional hub linking DNA repair to translation.iScience202642755940PubTator, text miningPubMed
A dual-channel FA1-targeting molecular rotor for orthogonal fluorescence sensing of microviscosity and human serum albumin in mitochondria.Chem Commun (Camb)202642747329PubTator, text miningPubMed
Establishing the First National Fanconi Anemia Registry in Iran: Clinical and Epidemiological Insights From 116 Patients.Pediatr Blood Cancer202642745671PubTator, text miningPubMed
Genetic variant profile in a cohort of inherited bone marrow failure patients from North india.Indian J Hematol Blood Transfus202642712617PubTator, text miningPubMed
Large-scale pleiotropic analysis across cancers reveals shared genetic mechanisms and identifies novel functional genes.Brief Bioinform202642704849PubTator, text miningPubMed
EIF1 coordinates transcriptomic and splicing networks associated with cell cycle dysregulation in diabetic retinopathy.PLoS One202642691050PubTator, text miningPubMed
Inflammatory Network Architecture Across Bone Marrow Failure: An Immune-Genetic Continuum.Front Biosci (Landmark Ed)202642689970PubTator, text miningPubMed

1 to 10 of 3,803

See all 3,803 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2175

GET https://conductscience.org/api/genes/v1/2175/patents?page=2