Gene · 2175
FANCA: FA complementation group A
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. FANCA: FA complementation group A. Genes, record 2175. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2175
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O15360 | Fanconi anemia group A protein | 1,455 | 6 | Ensembl, GeneID, HGNC |
Source UniProt
Patents28
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 10673 | O15360 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 11072 | O15360 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1528 | O15360 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1528 | O15360 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 11072 | O15360 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 10673 | O15360 | Espacenet |
| JP 2025510777 A | 2025-04-15 | 1 | O15360 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 6170 | O15360 | Espacenet |
| US 11976334 B2 | 2024-05-07 | 145 | O15360 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 30631 | O15360 | Espacenet |
1 to 10 of 28
See all 28 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,086
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | FANCA papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 71 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 34 | 2025 |
| R01HL052725 | Molecular Pathogenesis of Fanconi Anemia | 34 | 2025 |
| ZIACP010144 | Clinical Genetic Studies of Familial and Hereditary Cancer Syndromes | 19 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 17 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 14 | 2025 |
| ZIAAG000688 | Investigate the DNA damage response pathway of Fanconi anemia and BRCA proteins | 13 | 2025 |
| ZIAHG000029 | Fanconi Anemia: Genotype-Phenotype Correlations | 13 | 2025 |
| ZIAAG000741 | Roles Of DNA Helicases In Pathways Required For Maintenance Of Genomic Stability | 12 | 2025 |
| P50CA092629 | SPORE in Prostate Cancer | 11 | 2025 |
1 to 10 of 2,086Source NIH's project files
See all 2,086 nih grantsPapers3,803
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Evaluating interaction of pharmacologically potent organoselenides with transport protein human serum albumin: Spectroscopic and molecular dynamic simulations based mechanistic insights. | Spectrochim Acta A Mol Biomol Spectrosc | 2027 | 42790013 | PubTator, text mining | PubMed |
| Clinical, cytogenetic, and molecular insights from 32 years of the Portuguese Fanconi anemia cohort. | Genet Med Open | 2026 | 42824411 | PubTator, text mining | PubMed |
| FA1 site-targeted fluorescent probe for HSA detection and labeling: Biomedical applications and MD insights into local conformational perturbation. | Bioorg Chem | 2026 | 42772097 | PubTator, text mining | PubMed |
| Integrative proteomics defines FANCA as a multifunctional hub linking DNA repair to translation. | iScience | 2026 | 42755940 | PubTator, text mining | PubMed |
| A dual-channel FA1-targeting molecular rotor for orthogonal fluorescence sensing of microviscosity and human serum albumin in mitochondria. | Chem Commun (Camb) | 2026 | 42747329 | PubTator, text mining | PubMed |
| Establishing the First National Fanconi Anemia Registry in Iran: Clinical and Epidemiological Insights From 116 Patients. | Pediatr Blood Cancer | 2026 | 42745671 | PubTator, text mining | PubMed |
| Genetic variant profile in a cohort of inherited bone marrow failure patients from North india. | Indian J Hematol Blood Transfus | 2026 | 42712617 | PubTator, text mining | PubMed |
| Large-scale pleiotropic analysis across cancers reveals shared genetic mechanisms and identifies novel functional genes. | Brief Bioinform | 2026 | 42704849 | PubTator, text mining | PubMed |
| EIF1 coordinates transcriptomic and splicing networks associated with cell cycle dysregulation in diabetic retinopathy. | PLoS One | 2026 | 42691050 | PubTator, text mining | PubMed |
| Inflammatory Network Architecture Across Bone Marrow Failure: An Immune-Genetic Continuum. | Front Biosci (Landmark Ed) | 2026 | 42689970 | PubTator, text mining | PubMed |
1 to 10 of 3,803
See all 3,803 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2175
GET https://conductscience.org/api/genes/v1/2175/patents?page=2