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Gene · 2176

FANCC: FA complementation group C

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FANCC: FA complementation group C. Genes, record 2176. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2176

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Gene

Symbol
FANCC
HGNC
Name
FA complementation group C
HGNC
NCBI Gene ID
2176
NCBI Gene
HGNC ID
HGNC:3584
HGNC
Ensembl
ENSG00000158169
NCBI Gene
Aliases
FA3, FAC, FACC
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q00597Fanconi anemia group C protein5586Ensembl, GeneID, HGNC

Source UniProt

Patents24

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1445838Q00597Espacenet
JP 2026004568 A2026-01-1445839Q00597Espacenet
US 11976334 B22024-05-07147Q00597Espacenet
EP 4268831 A22023-11-01123Q00597Espacenet
US 11446398 B22022-09-2030656Q00597Espacenet
US 11446398 B22022-09-2030657Q00597Espacenet
JP 2022524081 A2022-04-27133627Q00597Espacenet
JP 2022524081 A2022-04-27133628Q00597Espacenet
US 11078247 B22021-08-033884Q00597Espacenet
EP 3849565 A12021-07-21123Q00597Espacenet

1 to 10 of 24

See all 24 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,492

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFANCC papersNewest fiscal year
P30CA008748Cancer Center Support Grant452025
R01HL052725Molecular Pathogenesis of Fanconi Anemia242025
ZIACP010144Clinical Genetic Studies of Familial and Hereditary Cancer Syndromes182025
P30CA016672Cancer Center Support Grant172025
ZIAAG000688Investigate the DNA damage response pathway of Fanconi anemia and BRCA proteins122025
ZIAHG000029Fanconi Anemia: Genotype-Phenotype Correlations112025
P30CA006973Regional Oncology Research Center92025
ZIAAG000741Roles Of DNA Helicases In Pathways Required For Maintenance Of Genomic Stability72025
ZIAAG000746Repair of localized DNA damage72025
ZIAAG000753Fanconi Anemia Pathway72025

1 to 10 of 1,492Source NIH's project files

See all 1,492 nih grants

Papers2,586

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Multi-Ancestry Genome-wide Association Analyses Identify Shared and Specific Genetic Architecture in Mild and Moderate-to-Severe Asthma.medRxiv202642818167PubTator, text miningPubMed
Gene by environment interaction effects on the metabolic subtype of Polycystic Ovary Syndrome in Hispanic Community Health Study/Study of Latinos.Front Genet202642730305PubTator, text miningPubMed
Structure and Dynamics of the HIV-1 Envelope Protein on the Virion Envelope.J Am Chem Soc202642677561PubTator, text miningPubMed
Uncovering Hereditary Risk: Germline Homologous Recombination Repair Variant Spectrum in a Large North Indian Cancer Cohort (INSIGHT-HRR).JCO Glob Oncol202642594331PubTator, text miningPubMed
Proposals for the #Enzian addendum and update: an international expert survey for item generation.Facts Views Vis Obgyn202642533569PubTator, text miningPubMed
Concordant high-grade glioma in monozygotic twins with germline variants in ATM, FANCC, and FANCM: a case report on combined DNA repair deficiency.Neurooncol Adv202642494996PubTator, text miningPubMed
Unlocking Sulforaphane's Potential in Friedreich Ataxia: Further Evidence from Preclinical Investigations Using Induced Pluripotent Stem Cell-Derived Sensory Neurons.Antioxid Redox Signal202642473835PubTator, text miningPubMed
Site-specific promoter hypermethylation of GPX4 in heart failure with reduced ejection fraction (HFrEF): nonlinear dose-response with hepatic and coagulation markers.Mol Biol Rep202642430008PubTator, text miningPubMed
Universal Germline Genetic Testing in a Precision Oncology and Rare Cancer Clinic: Implementation and Outcomes.JCO Oncol Adv202642422224PubTator, text miningPubMed
Proliferative ecotype determines lethal prognosis and therapeutic benefit in urothelial carcinoma.Cancer202642367015PubTator, text miningPubMed

1 to 10 of 2,586

See all 2,586 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2176

GET https://conductscience.org/api/genes/v1/2176/patents?page=2