Gene · 218
ALDH3A1: aldehyde dehydrogenase 3 family member A1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ALDH3A1: aldehyde dehydrogenase 3 family member A1. Genes, record 218. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/218
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P30838 | Aldehyde dehydrogenase 3A1 | 453 | 7 | Ensembl, GeneID, HGNC |
Source UniProt
Patents41
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 37017 | P30838 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 37022 | P30838 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 37023 | P30838 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 446 | P30838 | Espacenet |
| US 12378580 B2 | 2025-08-05 | 165 | P30838 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 446 | P30838 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 3875 | P30838 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 3878 | P30838 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 3880 | P30838 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 3875 | P30838 | Espacenet |
1 to 10 of 41
See all 41 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants929
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ALDH3A1 papers | Newest fiscal year |
|---|---|---|---|
| P30EY008098 | Core Grant for Vision Research | 13 | 2025 |
| R01AA011147 | Ethanol and aldehyde dehydrogenases in health and disease | 13 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 4 | 2025 |
| P30CA082709 | Indiana University Melvin and Bren Simon Comprehensive Cancer Center Support Grant | 4 | 2025 |
| P30ES013508 | Center of Excellence in Environmental Toxicology | 4 | 2025 |
| P30EY003790 | Core Grant for Vision Research | 4 | 2025 |
| P20GM103446 | Delaware INBRE | 3 | 2025 |
| P30CA016042 | Cancer Center Support Grant | 3 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 929Source NIH's project files
See all 929 nih grantsPapers1,555
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Uncovering sodium overload-associated gene signatures in chronic obstructive pulmonary disease through integrated bioinformatics and machine learning. | J Thorac Dis | 2026 | 42724664 | PubTator, text mining | PubMed |
| Circulating markers of organ damage associate with COPD in people with HIV: an exploratory proteomic analysis. | AIDS | 2026 | 42687556 | PubTator, text mining | PubMed |
| Bis-(di-4-phenyl-benzylaminethiocarbonyl)disulfide sensitizes ABCC2/ALDH3A1 overexpressing NSCLC cells to cisplatin. | Cancer Biol Ther | 2026 | 42474358 | PubTator, text mining | PubMed |
| Succinylation related gene signature enables risk stratification and prognostic modeling in breast cancer patients. | Amino Acids | 2026 | 42467271 | PubTator, text mining | PubMed |
| Comparative phenotypic and molecular characterization of primary, sv40-immortalized, and commercial human corneal keratocytes reveals a passage-dependent optimal window for in vitro applications. | Mol Biol Rep | 2026 | 42446752 | PubTator, text mining | PubMed |
| Spatial transcriptome and single-cell reveal the role of sorbitol metabolism in hepatocellular carcinoma progression and tumor microenvironment. | SLAS Technol | 2026 | 42413619 | PubTator, text mining | PubMed |
| Salivary Aldehyde Dehydrogenases in Oral Toxicology: Biological Functions, Disease Associations, and Translational Perspective. | Biology (Basel) | 2026 | 42345784 | PubTator, text mining | PubMed |
| Impact of Genetic Variants in Cyclophosphamide-Metabolizing Enzymes on Clinical Outcomes After Haploidentical Hematopoietic Stem Cell Transplantation. | Biomed J | 2026 | 42288135 | PubTator, text mining | PubMed |
| Integrating AI in Medicinal Chemistry for Accelerated Drug Discovery: A Comprehensive SAR (CSAR) Optimization Strategy and Discovery of Potent ALDH3A1 Inhibitors. | J Med Chem | 2026 | 42216908 | PubTator, text mining | PubMed |
| Association between air pollution exposure and increased chronic kidney disease risk: the modifying effects of genetic susceptibility, transcriptomic, and proteomic signatures. | BMC Med | 2026 | 42106700 | PubTator, text mining | PubMed |
1 to 10 of 1,555
See all 1,555 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/218
GET https://conductscience.org/api/genes/v1/218/patents?page=2