ConductScience.org, home

Gene · 218

ALDH3A1: aldehyde dehydrogenase 3 family member A1

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. ALDH3A1: aldehyde dehydrogenase 3 family member A1. Genes, record 218. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/218

On this page

Gene

Symbol
ALDH3A1
HGNC
Name
aldehyde dehydrogenase 3 family member A1
HGNC
NCBI Gene ID
218
NCBI Gene
HGNC ID
HGNC:405
HGNC
Ensembl
ENSG00000108602
NCBI Gene
Aliases
ALDH3, ALDHIII
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P30838Aldehyde dehydrogenase 3A14537Ensembl, GeneID, HGNC

Source UniProt

Patents41

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1437017P30838Espacenet
JP 2026004568 A2026-01-1437022P30838Espacenet
JP 2026004568 A2026-01-1437023P30838Espacenet
EP 4641201 A22025-10-29446P30838Espacenet
US 12378580 B22025-08-05165P30838Espacenet
JP 2025517969 A2025-06-12446P30838Espacenet
JP 2025062604 A2025-04-143875P30838Espacenet
JP 2025062604 A2025-04-143878P30838Espacenet
JP 2025062604 A2025-04-143880P30838Espacenet
US 11446398 B22022-09-203875P30838Espacenet

1 to 10 of 41

See all 41 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants929

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleALDH3A1 papersNewest fiscal year
P30EY008098Core Grant for Vision Research132025
R01AA011147Ethanol and aldehyde dehydrogenases in health and disease132025
P30CA016672Cancer Center Support Grant52025
P30CA047904Cancer Center Support Grant42025
P30CA082709Indiana University Melvin and Bren Simon Comprehensive Cancer Center Support Grant42025
P30ES013508Center of Excellence in Environmental Toxicology42025
P30EY003790Core Grant for Vision Research42025
P20GM103446Delaware INBRE32025
P30CA016042Cancer Center Support Grant32025
P30CA046934University of Colorado Cancer Center Support Grant32025

1 to 10 of 929Source NIH's project files

See all 929 nih grants

Papers1,555

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Uncovering sodium overload-associated gene signatures in chronic obstructive pulmonary disease through integrated bioinformatics and machine learning.J Thorac Dis202642724664PubTator, text miningPubMed
Circulating markers of organ damage associate with COPD in people with HIV: an exploratory proteomic analysis.AIDS202642687556PubTator, text miningPubMed
Bis-(di-4-phenyl-benzylaminethiocarbonyl)disulfide sensitizes ABCC2/ALDH3A1 overexpressing NSCLC cells to cisplatin.Cancer Biol Ther202642474358PubTator, text miningPubMed
Succinylation related gene signature enables risk stratification and prognostic modeling in breast cancer patients.Amino Acids202642467271PubTator, text miningPubMed
Comparative phenotypic and molecular characterization of primary, sv40-immortalized, and commercial human corneal keratocytes reveals a passage-dependent optimal window for in vitro applications.Mol Biol Rep202642446752PubTator, text miningPubMed
Spatial transcriptome and single-cell reveal the role of sorbitol metabolism in hepatocellular carcinoma progression and tumor microenvironment.SLAS Technol202642413619PubTator, text miningPubMed
Salivary Aldehyde Dehydrogenases in Oral Toxicology: Biological Functions, Disease Associations, and Translational Perspective.Biology (Basel)202642345784PubTator, text miningPubMed
Impact of Genetic Variants in Cyclophosphamide-Metabolizing Enzymes on Clinical Outcomes After Haploidentical Hematopoietic Stem Cell Transplantation.Biomed J202642288135PubTator, text miningPubMed
Integrating AI in Medicinal Chemistry for Accelerated Drug Discovery: A Comprehensive SAR (CSAR) Optimization Strategy and Discovery of Potent ALDH3A1 Inhibitors.J Med Chem202642216908PubTator, text miningPubMed
Association between air pollution exposure and increased chronic kidney disease risk: the modifying effects of genetic susceptibility, transcriptomic, and proteomic signatures.BMC Med202642106700PubTator, text miningPubMed

1 to 10 of 1,555

See all 1,555 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/218

GET https://conductscience.org/api/genes/v1/218/patents?page=2