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Gene · 2182

ACSL4: acyl-CoA synthetase long chain family member 4

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. ACSL4: acyl-CoA synthetase long chain family member 4. Genes, record 2182. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/2182

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
ACSL4
HGNC
Name
acyl-CoA synthetase long chain family member 4
HGNC
NCBI Gene ID
2182
NCBI Gene
HGNC ID
HGNC:3571
HGNC
Ensembl
ENSG00000068366
NCBI Gene
Aliases
ACS4, FACL4, LACS4, MRX63, MRX68, XLID63
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O60488Long-chain-fatty-acid--CoA ligase 47110Ensembl, GeneID, HGNC

Source UniProt

Patents58

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2025172069 A2025-11-2085O60488Espacenet
JP 2025172069 A2025-11-2086O60488Espacenet
EP 4650780 A22025-11-196472O60488Espacenet
JP 2025529142 A2025-09-04244O60488Espacenet
US 12371689 B22025-07-29244O60488Espacenet
JP 2025517970 A2025-06-126472O60488Espacenet
JP 2025062604 A2025-04-141967O60488Espacenet
JP 2025062604 A2025-04-141968O60488Espacenet
US 12247982 B22025-03-1185O60488Espacenet
US 12247982 B22025-03-1186O60488Espacenet

1 to 10 of 58

See all 58 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,092

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA008748Cancer Center Support Grant142025
R01NS076511Lipid Imaging in Traumatic Brain Injury by High Resolution GCIB-secondary Ion Mass Spectrometry122025
P30CA016672Cancer Center Support Grant112025
R01CA247992Targeting ferroptosis in radioresistance in lung cancer: mechanisms and preclinical translation102025
R01CA204232Ferroptosis, Cellular Metabolism, and Cancer82025
R01GM122923Characterizing the Regulation of Ferroptosis82025
P30CA010815Consolidated Basic Cancer Research Program62025
P42ES004940The DUST Center: Hazardous Dust in Drylands - Exposure, Health Impacts, and Mitigation52025
P30CA013696Cancer Center Support Grant42025
P30ES006694Southwest Environmental Health Sciences Center42025

1 to 10 of 1,092Source NIH's project files

See all 1,092 nih grants

Papers4,043

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827074PubTator, text miningPubMed
42826479PubTator, text miningPubMed
42825017PubTator, text miningPubMed
42822756PubTator, text miningPubMed
42822540PubTator, text miningPubMed
42807112PubTator, text miningPubMed
42803694PubTator, text miningPubMed
42802387PubTator, text miningPubMed
42792788PubTator, text miningPubMed
42789330PubTator, text miningPubMed

1 to 10 of 4,043

See all 4,043 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

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GET https://conductscience.org/api/genes/v1/2182/patents?page=2