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ACSL4: acyl-CoA synthetase long chain family member 4
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Gene · 2182

Papers4,043

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

141 to 160 of 4,043

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TitleJournalYearPMIDFound bySource
Iron-mediated ferroptosis impairs CAR-T cell function and antitumor efficacy.Nat Cancer202642270901PubTator, text miningPubMed
Chrysin Attenuates Dry Eye Progression by Suppressing NOX2-Dependent Ferroptosis and STING/NLRP3-Mediated Inflammatory Responses.Invest Ophthalmol Vis Sci202642267783PubTator, text miningPubMed
Cell size modulates ferroptosis susceptibility.Elife202642267631PubTator, text miningPubMed
Combination drug therapy reduces iron accumulation and microglia-mediated pathologies in neonatal intraventricular hemorrhage: a biochemical and transcriptomic analysis.Front Cell Neurosci202642266249PubTator, text miningPubMed
Progress of Traditional Chinese Medicine in Targeting Ferroptosis to Combat Cerebral Ischemia-Reperfusion Injury.Am J Chin Med202642261256PubTator, text miningPubMed
[Polydatin attenuates high copper induced damage in Atp7b knockout neural stem cells by regulating PPARG mediated ferroptosis].Zhejiang Da Xue Xue Bao Yi Xue Ban202642260313PubTator, text miningPubMed
ACSL4-driven ferroptosis susceptibility as a targetable vulnerability in monocytic acute myeloid leukemia.Front Oncol202642255227PubTator, text miningPubMed
Ferroptosis: an emerging key mechanism linking aging, surgical and anesthetic exposure to postoperative cognitive dysfunction.Front Immunol202642254023PubTator, text miningPubMed
Andrographolide Suppresses Head and Neck Squamous Cell Carcinoma Progression via EGR1-ACSL4 Axis-Mediated Ferroptosis.Am J Chin Med202642252950PubTator, text miningPubMed
Transcription factor STAT1 upregulates IL-36γ to mediate the sensitivity of human nasal epithelial cells to ferroptosis and promote inflammatory progression in chronic rhinosinusitis.Mol Immunol202642247985PubTator, text miningPubMed
Association of Serum Angiopoietin-Like Protein 7 With Ferroptosis-Related Proteins in Patients With Metabolic Dysfunction-Associated Fatty Liver Disease.FASEB J202642247282PubTator, text miningPubMed
Gut microbiota-derived short-chain fatty acids attenuate placental ferroptosis and insulin resistance in gestational diabetes via the ACSL4/LPCAT3 pathway.Front Microbiol202642245515PubTator, text miningPubMed
Huaier counteracts sorafenib resistance in hepatocellular carcinoma by activating NCOA4-mediated ferritinophagy to induce ferroptosis via modulation of iron and lipid metabolism.Biochim Biophys Acta Mol Basis Dis202642242436PubTator, text miningPubMed
Metformin and Placental Ferroptosis in Gestational Diabetes: A Mechanistic Study.J Diabetes Res202642237524PubTator, text miningPubMed
Ferroptosis in cancer: integrating multi-omics, AI-driven biomarkers, and translational challenges.Clin Chim Acta202642229709PubTator, text miningPubMed
Clinical significance of immunocyte- and ferroptosis-related markers for the prognosis of patients with tenosynovial giant cell tumor: A cross-sectional study.Cancer Treat Res Commun202642229264PubTator, text miningPubMed
Ferroptosis promotes aortic stenosis through 5-lipoxygenase.Eur Heart J202642227114PubTator, text miningPubMed
Ferroptosis in breast cancer: From adipocyte-immune-iron regulation to therapeutic application.Clin Transl Med202642226605PubTator, text miningPubMed
Energy Stress-Induced Neuroprotection Against Ferroptosis in Dopaminergic Neurons.J Neurochem202642223207PubTator, text miningPubMed
Targeting Ferroptosis for Cerebral Neuroprotection in Ischemic Stroke: Pathophysiological Insights.Int J Gen Med202642221841PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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