ConductScience.org, home

Gene · 2188

FANCF: FA complementation group F

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. FANCF: FA complementation group F. Genes, record 2188. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2188

On this page

Gene

Symbol
FANCF
HGNC
Name
FA complementation group F
HGNC
NCBI Gene ID
2188
NCBI Gene
HGNC ID
HGNC:3587
HGNC
Ensembl
ENSG00000183161
NCBI Gene
Aliases
FAF
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9NPI8Fanconi anemia group F protein3747Ensembl, GeneID, HGNC

Source UniProt

Patents26

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1445846Q9NPI8Espacenet
US 11976334 B22024-05-07150Q9NPI8Espacenet
EP 4268831 A22023-11-01125Q9NPI8Espacenet
US 11446398 B22022-09-2030668Q9NPI8Espacenet
JP 2022524081 A2022-04-27133639Q9NPI8Espacenet
US 11078247 B22021-08-033887Q9NPI8Espacenet
EP 3849565 A12021-07-21125Q9NPI8Espacenet
US 11047010 B22021-06-292378Q9NPI8Espacenet
US 10865447 B22020-12-152378Q9NPI8Espacenet
JP 2020517720 A2020-06-1858Q9NPI8Espacenet

1 to 10 of 26

See all 26 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants834

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFANCF papersNewest fiscal year
R01HL052725Molecular Pathogenesis of Fanconi Anemia152025
P30CA016672Cancer Center Support Grant142025
ZIACP010144Clinical Genetic Studies of Familial and Hereditary Cancer Syndromes132025
ZIAAG000688Investigate the DNA damage response pathway of Fanconi anemia and BRCA proteins112025
P30CA008748Cancer Center Support Grant102025
RM1HG009490Center for Genomic Editing and Recording: Development and Application of Next-Generation Genome and Epigenome Editing Methods to Advance the Study and Treatment of Human Disease102025
ZIAHG000029Fanconi Anemia: Genotype-Phenotype Correlations92025
P30CA006973Regional Oncology Research Center82025
R35GM118062Integrating Chemistry and Evolution to Illuminate Biology and Enable Novel Therapeutics82025
P01CA092584Structural Cell Biology of DNA Repair Machines72025

1 to 10 of 834Source NIH's project files

See all 834 nih grants

Papers1,147

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Micronuclei: origins, assays, mechanisms, diseases and treatments.Signal Transduct Target Ther202641888103PubTator, text miningPubMed
Unraveling cellular longevity pathways in poultry under heat stress: functional and computational characterization of the adaptogenic formulation Phytocee™.In Silico Pharmacol202641852713PubTator, text miningPubMed
Genome-wide CRISPR screens identify the EXO1-CAF-1 pathway suppressing R-loop-associated DNA damage.Nucleic Acids Res202641841497PubTator, text miningPubMed
Prognostic Significance of DNA Repair Gene mRNA Expression in Early-Stage Breast Cancer: Insights into Clinical Relevance.Oncol Res202641799499PubTator, text miningPubMed
Advances in Engineered Virus-Like Particles for Genome Editing and Therapy.BioDrugs202641733889PubTator, text miningPubMed
Whole genome sequencing approach to assess homologous recombination deficiency in a pan-cancer cohort.Commun Med (Lond)202641526458PubTator, text miningPubMed
Integrating CRISPR/Cas technology with clinical trials: Principles, progress and challenges.Asian J Pharm Sci202541809894PubTator, text miningPubMed
CSRNP1 Promotes Apoptosis and Mitochondrial Dysfunction via ROS-Mediated JNK/p38 MAPK Pathway Activation in Hepatocellular Carcinoma.Oncol Res202541502527PubTator, text miningPubMed
AI-driven advances in plant biotechnology: sharpening the edge of plant tissue culture and genome editing.Front Plant Sci202541451278PubTator, text miningPubMed
TSN Disrupts Fanconi Anemia Pathway Activation Through JAK/STAT1-Mediated Transcriptional Repression of FA Core Subunits in Bladder Cancer.Dose Response202541346410PubTator, text miningPubMed

1 to 10 of 1,147

See all 1,147 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2188

GET https://conductscience.org/api/genes/v1/2188/patents?page=2