ConductScience.org, home

Gene · 2189

FANCG: FA complementation group G

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. FANCG: FA complementation group G. Genes, record 2189. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2189

On this page

Gene

Symbol
FANCG
HGNC
Name
FA complementation group G
HGNC
NCBI Gene ID
2189
NCBI Gene
HGNC ID
HGNC:3588
HGNC
Ensembl
ENSG00000221829
NCBI Gene
Aliases
FAG, XRCC9
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O15287Fanconi anemia group G protein6226Ensembl, GeneID, HGNC

Source UniProt

Patents31

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2025038035 A2025-03-184366O15287Espacenet
US 12134655 B22024-11-054366O15287Espacenet
JP 2024123008 A2024-09-106174O15287Espacenet
US 11976334 B22024-05-07151O15287Espacenet
EP 4268831 A22023-11-01126O15287Espacenet
US 11446398 B22022-09-2030669O15287Espacenet
JP 2022530667 A2022-06-304366O15287Espacenet
JP 2022524081 A2022-04-27133640O15287Espacenet
US 11078247 B22021-08-033888O15287Espacenet
EP 3849565 A12021-07-21126O15287Espacenet

1 to 10 of 31

See all 31 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants852

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFANCG papersNewest fiscal year
R01HL052725Molecular Pathogenesis of Fanconi Anemia252025
P30CA008748Cancer Center Support Grant152025
ZIACP010144Clinical Genetic Studies of Familial and Hereditary Cancer Syndromes122025
P30CA016672Cancer Center Support Grant112025
ZIAAG000688Investigate the DNA damage response pathway of Fanconi anemia and BRCA proteins102025
ZIAHG000029Fanconi Anemia: Genotype-Phenotype Correlations102025
ZIAAG000746Repair of localized DNA damage82025
P01CA092584Structural Cell Biology of DNA Repair Machines72025
P30CA006973Regional Oncology Research Center72025
ZICHG200346NHGRI/DIR Genomics Core72025

1 to 10 of 852Source NIH's project files

See all 852 nih grants

Papers1,427

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Clinical, cytogenetic, and molecular insights from 32 years of the Portuguese Fanconi anemia cohort.Genet Med Open202642824411PubTator, text miningPubMed
ZMAT3 alleviates cell death in Fanconi anemia via adaptation of sphingolipid metabolism.Sci Adv202642536749PubTator, text miningPubMed
Site-Specific Genomic Markers Associated with Outcomes of PD-1 Blockade in Gastric and Esophagogastric Junction Cancer: Analysis of Japan's C-CAT Registry.BioDrugs202642045774PubTator, text miningPubMed
Integrative Analysis of Telomere-Related Genes Reveals Prognostic Signatures in Laryngeal Cancer.Int J Genomics202641959623PubTator, text miningPubMed
Micronuclei: origins, assays, mechanisms, diseases and treatments.Signal Transduct Target Ther202641888103PubTator, text miningPubMed
Comprehensive Genomic Profiling Across Diverse Solid Tumors: A Real-World Experience From India With FoundationOne®CDx Testing.Cureus202641717185PubTator, text miningPubMed
Whole Exome Sequencing Revealed Rare Variants in BRCA2, RAD51D, FANGC, CYP24A1 Genes in Breast/Ovarian Cancer Patients from a Small Buryat Ethnic Group.Asian Pac J Cancer Prev202641660923PubTator, text miningPubMed
Comparison of Familial and Sporadic Pancreatic Cancer: Clinicopathological and Genomic Features.Ann Surg Oncol202641085800PubTator, text miningPubMed
Pathogenic variants reveal candidate genes for prostate cancer germline testing for men of African ancestry.Nat Commun202541038821PubTator, text miningPubMed
EXO1 as a therapeutic target for Fanconi Anaemia, ZRSR2 and BRCA1-A complex deficient cancers.Nat Commun202541006228PubTator, text miningPubMed

1 to 10 of 1,427

See all 1,427 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2189

GET https://conductscience.org/api/genes/v1/2189/patents?page=2