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Gene · 2192

FBLN1: fibulin 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FBLN1: fibulin 1. Genes, record 2192. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2192

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Gene

Symbol
FBLN1
HGNC
Name
fibulin 1
HGNC
NCBI Gene ID
2192
NCBI Gene
HGNC ID
HGNC:3600
HGNC
Ensembl
ENSG00000077942
NCBI Gene
Aliases
FBLN, FIBL1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P23142Fibulin-17030Ensembl, GeneID, HGNC

Source UniProt

Patents30

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026515744 A2026-05-19295P23142Espacenet
JP 2026004568 A2026-01-1446303P23142Espacenet
EP 4650780 A22025-11-195912P23142Espacenet
EP 4640849 A22025-10-29858P23142Espacenet
EP 4641201 A22025-10-295635P23142Espacenet
JP 2025147176 A2025-10-065128P23142Espacenet
JP 2025529142 A2025-09-046343P23142Espacenet
US 12371689 B22025-07-296343P23142Espacenet
JP 2025519096 A2025-06-24858P23142Espacenet
JP 2025517969 A2025-06-125635P23142Espacenet

1 to 10 of 30

See all 30 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,030

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFBLN1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant52025
P30CA016672Cancer Center Support Grant42025
P30CA046934University of Colorado Cancer Center Support Grant42025
P30EY005722Center Core Grant for Vision Research42025
P50CA097186The Pacific Northwest Prostate Cancer SPORE42025
P20GM103499South Carolina IDeA Networks of Biomedical Research Excellence (SC INBRE)32025
P30CA068485Cancer Center Support Grant32025
T32GM008315Mechanisms of Trauma-Induced Coagulopathy32025
P30CA015704Cancer Center Support Grant22025
P30CA016058Cancer Center Support Grant22025

1 to 10 of 1,030Source NIH's project files

See all 1,030 nih grants

Papers1,552

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
FBLN1 Regulates Embryonic Myoblast Proliferation and Differentiation in Geese: Functional Characterization of a Meat Quality-Associated Candidate Gene From Prior Multi-Omics Screening.Anim Genet202642806296PubTator, text miningPubMed
Distinct changes in plasma protein profiles of cancer patients receiving immune checkpoint inhibitors versus chemotherapy: implications for thrombosis risk and adverse outcomes.Res Pract Thromb Haemost202642787640PubTator, text miningPubMed
Spatial compartmentalization of melanoma cell states reveals CAF-associated tumor cells with enhanced proliferative capacity.PLoS One202642743160PubTator, text miningPubMed
Single-cell transcriptomics deciphers cancer-associated fibroblast heterogeneity and immune regulatory mechanisms in the bladder cancer tumor microenvironment.Front Cell Dev Biol202642729537PubTator, text miningPubMed
Integrative transcriptomic identification of potential common biomarkers between non-obstructive azoospermia and papillary thyroid cancer via multi-algorithmic machine learning and network biology approaches.
Cancer Treat Res Commun202642710154PubTator, text miningPubMed
Fibulin-1 Improves Caerulein-Induced Acute Pancreatitis In Vitro by Inhibiting Ferroptosis.J Biochem Mol Toxicol202642670805PubTator, text miningPubMed
Immortalized smooth muscle cells enhance in vitro vasculogenesis.Angiogenesis202642622755PubTator, text miningPubMed
Impact of IL-5 Pathway Inhibition on Circulating Eosinophil- and Remodeling-Related Biomarkers in Severe Eosinophilic Asthma.J Asthma Allergy202642609892PubTator, text miningPubMed
Fibulin-1 is required for microvascular integrity in the developing brain and retina.Dev Biol202642542239PubTator, text miningPubMed
Identification of distinct gene and miRNA expression profiles in severe early-onset COPD providing novel insights in disease pathogenesis.Thorax202642481400PubTator, text miningPubMed

1 to 10 of 1,552

See all 1,552 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2192

GET https://conductscience.org/api/genes/v1/2192/patents?page=2