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FASN: fatty acid synthase

1 protein, 68 patents, 0 drugs, 0 trials, 6,097 NIH grants and 13,826 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolFASNHGNC
Namefatty acid synthaseHGNC
NCBI Gene ID2194NCBI Gene
HGNC IDHGNC:3594HGNC
EnsemblENSG00000169710NCBI Gene
AliasesFAS, OA-519, SDR27X1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P49327Fatty acid synthase2,51134Ensembl, GeneID, HGNCUniProt

Patents 68

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-194288P49327Espacenet
EP 4640849 A22025-10-29558P49327Espacenet
EP 4641201 A22025-10-293838P49327Espacenet
EP 4641202 A22025-10-294797P49327Espacenet
JP 2025147176 A2025-10-0616509P49327Espacenet
JP 2025519096 A2025-06-24558P49327Espacenet
JP 2025517969 A2025-06-123838P49327Espacenet
JP 2025517970 A2025-06-124288P49327Espacenet
JP 2025028160 A2025-02-2816509P49327Espacenet
KR 1020250017231 A2025-02-044797P49327Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 6097

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant652,025NIH's project files
P30DK026743UCSF Liver Center282,025NIH's project files
P30CA008748Cancer Center Support Grant272,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant242,025NIH's project files
P30DK056341Washington University Nutrition Obesity Research Center242,025NIH's project files
P30DK020572Michigan Diabetes Research Center (MDRC)222,025NIH's project files
P30DK048520Colorado Nutrition Obesity Research Center222,025NIH's project files
P30DK020579Diabetes Research Center212,025NIH's project files
P20GM113226Hepatobiology and Toxicology COBRE192,025NIH's project files
P30CA006973Regional Oncology Research Center182,025NIH's project files

Papers 13826

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826791PubTator, text miningPubMed
42824032PubTator, text miningPubMed
42818361PubTator, text miningPubMed
42813828PubTator, text miningPubMed
42812879PubTator, text miningPubMed
42801443PubTator, text miningPubMed
42801336PubTator, text miningPubMed
42798652PubTator, text miningPubMed
42798608PubTator, text miningPubMed
42793239PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license