Gene · 22
ABCB7: ATP binding cassette subfamily B member 7
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ABCB7: ATP binding cassette subfamily B member 7. Genes, record 22. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/22
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O75027 | Iron-sulfur clusters transporter ABCB7, mitochondrial | 752 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents14
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 38389 | O75027 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 9544 | O75027 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 193 | O75027 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 193 | O75027 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 9544 | O75027 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 7662 | O75027 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 7662 | O75027 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 110633 | O75027 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 47 | O75027 | Espacenet |
| WO 2020043864 A1 | 2020-03-05 | 41 | O75027 | Espacenet |
1 to 10 of 14
See all 14 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants661
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ABCB7 papers | Newest fiscal year |
|---|---|---|---|
| ZIAHD008814 | Mammalian iron-sulfur cluster biogenesis | 11 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 10 | 2025 |
| ZIAHD001602 | Regulation Of Intracellular Iron Metabolism | 8 | 2025 |
| R01HL128239 | Genetic and molecular basis for SRSF2 mutations in myelodysplasia | 5 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 3 | 2025 |
| R35GM118136 | Regulation of mRNA processing: Mechanisms and Consequences | 3 | 2025 |
| T32DK007665 | Metabolism and Nutrition Training Program | 3 | 2025 |
| P30CA016087 | Cancer Center Support Grant | 2 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 2 | 2025 |
| P30CA086862 | Cancer Center Support Grant | 2 | 2025 |
1 to 10 of 661Source NIH's project files
See all 661 nih grantsPapers2,216
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Early liver parameter increase after transjugular intrahepatic portosystemic shunt (TIPS): hepatic vascular risk factors and development of an exploratory prediction model. | Abdom Radiol (NY) | 2026 | 42771039 | PubTator, text mining | PubMed |
| Lugol's Iodine as a Key Treatment in Transient Gestational Thyrotoxicosis: A Case Report. | Case Rep Endocrinol | 2026 | 42466308 | PubTator, text mining | PubMed |
| Effects of mitochondrial ABCB7 transporter upregulation on acute doxorubicin cardiorespiratory muscle injury. | J Appl Physiol (1985) | 2026 | 42441500 | PubTator, text mining | PubMed |
| Cryo-EM structures of human ABCB7 reveal the molecular basis of mitochondrial matrix heme export. | Commun Biol | 2026 | 42103889 | PubTator, text mining | PubMed |
| Combined elevation of pre-treatment γ-glutamyltransferase and lactate dehydrogenase as independent prognosticator for metastatic renal cell carcinoma undergoing immune-based therapy. | Sci Rep | 2026 | 42000841 | PubTator, text mining | PubMed |
| Markers for the Severity of Multisystem Inflammatory Syndrome in Children: A Multivariate Analysis. | Int J Pediatr | 2026 | 41969283 | PubTator, text mining | PubMed |
| Profiles of patients at early stages of Huntington's disease based on the routine biological markers and the disease progression. | J Neurol | 2026 | 41928019 | PubTator, text mining | PubMed |
| The power of lifestyle intervention to induce glycaemic control in a patient with newly diagnosed type 2 diabetes and HbA1c >10. | Endocrinol Diabetes Metab Case Rep | 2026 | 41925329 | PubTator, text mining | PubMed |
| The regulation of mitochondrial ferritin on mitochondrial redox balance is essential to cell fate decision. | Redox Biol | 2026 | 41844496 | PubTator, text mining | PubMed |
| MASLD Is Associated With Decreased General Health Perception, Quality of Life and Work Productivity in a Low Fibrosis Population. | Liver Int | 2026 | 41841378 | PubTator, text mining | PubMed |
1 to 10 of 2,216
See all 2,216 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/22
GET https://conductscience.org/api/genes/v1/22/patents