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Gene · 220

ALDH1A3: aldehyde dehydrogenase 1 family member A3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ALDH1A3: aldehyde dehydrogenase 1 family member A3. Genes, record 220. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/220

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Gene

Symbol
ALDH1A3
HGNC
Name
aldehyde dehydrogenase 1 family member A3
HGNC
NCBI Gene ID
220
NCBI Gene
HGNC ID
HGNC:409
HGNC
Ensembl
ENSG00000184254
NCBI Gene
Aliases
ALDH1A6, ALDH6, MCOP8, RALDH3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P47895Retinaldehyde dehydrogenase 351210Ensembl, GeneID, HGNC

Source UniProt

Patents23

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1436996P47895Espacenet
EP 4650780 A22025-11-195958P47895Espacenet
EP 4641201 A22025-10-295692P47895Espacenet
JP 2025517969 A2025-06-125692P47895Espacenet
JP 2025517970 A2025-06-125958P47895Espacenet
JP 2025062604 A2025-04-143841P47895Espacenet
JP 2025032204 A2025-03-1124385P47895Espacenet
EP 4461818 A22024-11-1324385P47895Espacenet
JP 2023058610 A2023-04-2524385P47895Espacenet
JP 2022147356 A2022-10-06209P47895Espacenet

1 to 10 of 23

See all 23 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,350

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleALDH1A3 papersNewest fiscal year
P30CA016672Cancer Center Support Grant102025
P30CA016058Cancer Center Support Grant82025
R01AA011147Ethanol and aldehyde dehydrogenases in health and disease82025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202872025
P30CA046934University of Colorado Cancer Center Support Grant72025
P30CA086862Cancer Center Support Grant62025
P30CA006973Regional Oncology Research Center52025
P30CA008748Cancer Center Support Grant52025
P30CA022453CANCER CENTER SUPPORT GRANT52025
P30DK063608Columbia Diabetes Research Center52025

1 to 10 of 1,350Source NIH's project files

See all 1,350 nih grants

Papers1,919

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
First Report of Uniparental Isodisomy of Chromosome 15 Revealing Angelman Syndrome and Microphthalmia Associated With a Novel Homozygous ALDH1A3 Variant.Am J Med Genet A202642757722PubTator, text miningPubMed
A retinoic acid autoregulatory loop governing prefrontal-motor arealization.Nature202642749810PubTator, text miningPubMed
Host eicosanoid signals define a granuloma fibroblast population that coordinates mycobacterial containment.Cell Host Microbe202642641606PubTator, text miningPubMed
Circular RNA-Mediated ceRNA networks predict sperm retrieval outcomes in non-obstructive azoospermia.J Assist Reprod Genet202642623004PubTator, text miningPubMed
Abexinostat attenuates temozolomide-resistant glioma stem cells.Neuro Oncol202642616000PubTator, text miningPubMed
Transcriptome profiling of ocular surface ectoderm derived from embryonic stem cells, and identification of CACNG6 and AQP3 as its surface markers.Int J Ophthalmol202642523845PubTator, text miningPubMed
Evaluating KRAS-Associated Responses to Sulfasalazine and 5-Fluorouracil in Colorectal Cancer Using Integrated 2D and PEGDA Microwell-Based 3D Tumor Models.Int J Mol Sci202642511582PubTator, text miningPubMed
Baculoviral Inhibitor of Apoptosis Repeat Containing 5 (BIRC5) Regulates Cancer Stem Cell Properties and Epithelial-Mesenchymal Transition in Human Breast Cancer Cells.Dev Reprod202642445845PubTator, text miningPubMed
EphA2 sustains the adaptive response of colorectal organoids to chemotherapy.Front Cell Dev Biol202642368451PubTator, text miningPubMed
A Novel Signaling Driven by the Stem Cell Marker ALDH1A3 Promotes Glioblastoma Cell Mobility.Cells202642346106PubTator, text miningPubMed

1 to 10 of 1,919

See all 1,919 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/220

GET https://conductscience.org/api/genes/v1/220/patents?page=2