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FBN1: fibrillin 1

1 protein, 71 patents, 0 drugs, 0 trials, 2,987 NIH grants and 6,683 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolFBN1HGNC
Namefibrillin 1HGNC
NCBI Gene ID2200NCBI Gene
HGNC IDHGNC:3603HGNC
EnsemblENSG00000166147NCBI Gene
AliasesACMICD, ECTOL1, FBN, GPHYSD2, MASS, MFLS, MFS1, OCTD, SGS, SSKS, WMS, WMS2NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P35555Fibrillin-12,87111Ensembl, GeneID, HGNCUniProt

Patents 71

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026042028 A2026-03-1062P35555Espacenet
EP 4650780 A22025-11-195614P35555Espacenet
EP 4641201 A22025-10-295253P35555Espacenet
JP 2025147176 A2025-10-065154P35555Espacenet
JP 2025529142 A2025-09-046347P35555Espacenet
US 12371689 B22025-07-296347P35555Espacenet
JP 2025517969 A2025-06-125253P35555Espacenet
JP 2025517970 A2025-06-125614P35555Espacenet
JP 2025032204 A2025-03-1128289P35555Espacenet
JP 2025028160 A2025-02-285154P35555Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2987

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30EY010572Ophthalmology Core Facility132,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award102,025NIH's project files
UL1TR001881UCLA Clinical and Translational Science Institute82,025NIH's project files
P30CA016672Cancer Center Support Grant72,025NIH's project files
R01EY019643Extracellular Matrix and Outflow Resistance72,025NIH's project files
P30CA042014Cancer Center Support Grant62,025NIH's project files
P30EY001792P30 Core Grant for Vision Research62,025NIH's project files
P30EY014801Miami Center for Vision Research62,025NIH's project files
P01HD084387Developmental Mechanisms of Human Idiopathic Scoliosis52,025NIH's project files
P30CA008748Cancer Center Support Grant52,025NIH's project files

Papers 6683

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42820018PubTator, text miningPubMed
42814914PubTator, text miningPubMed
42808166PubTator, text miningPubMed
42799944PubTator, text miningPubMed
42798042PubTator, text miningPubMed
42794655PubTator, text miningPubMed
42784441PubTator, text miningPubMed
42780480PubTator, text miningPubMed
42773793PubTator, text miningPubMed
42761014PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license