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Gene · 2201

FBN2: fibrillin 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FBN2: fibrillin 2. Genes, record 2201. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2201

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Gene

Symbol
FBN2
HGNC
Name
fibrillin 2
HGNC
NCBI Gene ID
2201
NCBI Gene
HGNC ID
HGNC:3604
HGNC
Ensembl
ENSG00000138829
NCBI Gene
Aliases
CCA, DA9, EOMD
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P35556Fibrillin-22,9120Ensembl, GeneID, HGNC

Source UniProt

Patents92

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026042028 A2026-03-1063P35556Espacenet
JP 2026004568 A2026-01-1446205P35556Espacenet
JP 2026004568 A2026-01-1446206P35556Espacenet
EP 4650780 A22025-11-192077P35556Espacenet
EP 4641201 A22025-10-291640P35556Espacenet
JP 2025147176 A2025-10-065157P35556Espacenet
JP 2025147176 A2025-10-065159P35556Espacenet
JP 2025529142 A2025-09-046348P35556Espacenet
US 12371689 B22025-07-296348P35556Espacenet
JP 2025517969 A2025-06-121640P35556Espacenet

1 to 10 of 92

See all 92 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,526

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFBN2 papersNewest fiscal year
P30CA008748Cancer Center Support Grant82025
P30CA016672Cancer Center Support Grant82025
UL1TR001863Yale Clinical and Translational Science Award72025
P40OD010440Caenorhabditis Genetics Center62025
R01AR072009Investigations of the molecular genetics and pathogenesis of scoliosis.52025
P01HD084387Developmental Mechanisms of Human Idiopathic Scoliosis42025
P30EY010572Ophthalmology Core Facility42025
P01AI063302The intersection of innate and adaptive immunity to intracellular pathogens32025
P30CA006973Regional Oncology Research Center32025
P30CA014051Cancer Center Support (Core) Grant32025

1 to 10 of 1,526Source NIH's project files

See all 1,526 nih grants

Papers2,084

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Sclerostin regulates bone morphogenetic protein (BMP) bioavailability through interactions with BMP complexes and fibrillin microfibrils.FEBS J202642808166PubTator, text miningPubMed
Identification and evolutionary analysis of insect fibrillin with their closely related family proteins.PeerJ202642668958PubTator, text miningPubMed
Spontaneous spinal CSF leaks: a rare variant exome sequencing study and functional analysis.Lancet Neurol202642309087PubTator, text miningPubMed
Case Report: A novel variant in fibrillin-2 identified in a congenital contractural arachnodactyly family with phenotypic heterogeneity.Front Med (Lausanne)202642305963PubTator, text miningPubMed
Two Novel FBN2 Variants Causing Congenital Contractural Arachnodactyly.Genet Res (Camb)202642299845PubTator, text miningPubMed
Cardiovascular and Clinical Manifestations of Marfan Syndrome and Other Inherited Connective Tissue Disorders with Coexisting Genetic Variants.Cells202642274593PubTator, text miningPubMed
Microfibril Denudation Marks Early Aortic Vulnerability in SMAD3 Variant Carriers: A Multigenerational Study.Arterioscler Thromb Vasc Biol202642273728PubTator, text miningPubMed
Extracellular matrix gene variants and susceptibility to sport-related musculoskeletal injuries.J Appl Genet202642209954PubTator, text miningPubMed
Genetic Polymorphisms in Systemic Lupus Erythematosus and Their Clinical Implications: A Narrative Review.Int J Mol Sci202642123548PubTator, text miningPubMed
Integrated clinicopathological, genomic, and immunophenotypic landscape of renal tubulocystic oncocytoma.Front Immunol202642058215PubTator, text miningPubMed

1 to 10 of 2,084

See all 2,084 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2201

GET https://conductscience.org/api/genes/v1/2201/patents?page=2