Gene · 2203
FBP1: fructose-bisphosphatase 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. FBP1: fructose-bisphosphatase 1. Genes, record 2203. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2203
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P09467 | Fructose-1,6-bisphosphatase 1 | 338 | 51 | Ensembl, GeneID, HGNC |
Source UniProt
Patents49
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026067851 A | 2026-04-21 | 157 | P09467 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 46720 | P09467 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 46722 | P09467 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 9606 | P09467 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 9861 | P09467 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 5639 | P09467 | Espacenet |
| WO 2025176691 A1 | 2025-08-28 | 10 | P09467 | Espacenet |
| WO 2025142929 A | 2025-07-03 | 1 | P09467 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 9861 | P09467 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 9606 | P09467 | Espacenet |
1 to 10 of 49
See all 49 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,213
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | FBP1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 17 | 2025 |
| R35CA220483 | Metabolic Influences on Complex Tumor Neighborhoods | 9 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| P30CA177558 | University of Kentucky Markey Cancer Center – Cancer Center Support Grant | 7 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 4 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 4 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 4 | 2025 |
| P30DK045735 | Yale Diabetes Research Center | 4 | 2025 |
| P30ES017885 | Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD) | 4 | 2025 |
| R01DK133448 | The NRF2-FBP1 crossregulatory loop and the control of healthy and diseased liver metabolism | 4 | 2025 |
1 to 10 of 1,213Source NIH's project files
See all 1,213 nih grantsPapers2,174
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Fructose-1,6-bisphosphatase deficiency: the clinical characteristics, molecular consequences of FBP1 variants, and emerging non-canonical functions of FBP1. | Endocr J | 2026 | 42816337 | PubTator, text mining | PubMed |
| Gene by environment interaction effects on the metabolic subtype of Polycystic Ovary Syndrome in Hispanic Community Health Study/Study of Latinos. | Front Genet | 2026 | 42730305 | PubTator, text mining | PubMed |
| Multi-omics integration uncovers epigenetic control of metabolic reprogramming in triple-negative breast cancer. | J Egypt Natl Canc Inst | 2026 | 42684639 | PubTator, text mining | PubMed |
| Effects of different dietary metabolizable energy levels on growth performance, liver metabolism, and gut microbiota in growing broilers. | Poult Sci | 2026 | 42603396 | PubTator, text mining | PubMed |
| Circadian Regulation of Glucose Metabolism: Implications for Pathogenesis and Chronotherapy of Type 2 Diabetes. | Diabetology (Basel) | 2026 | 42583078 | PubTator, text mining | PubMed |
| Fructose-1,6-bisphosphatase as a therapeutic target for type 2 diabetes: from molecular mechanisms to clinical translation. | Arch Physiol Biochem | 2026 | 42559717 | PubTator, text mining | PubMed |
| Integrating Genetic Data and Electronic Medical Records to Reassess Variant Pathogenicity in the Taiwanese Han Population. | Genes (Basel) | 2026 | 42510858 | PubTator, text mining | PubMed |
| Roles of the E3 Ubiquitin Ligase TRIM47 in Inflammation, Organ Injury, and Cancer. | FASEB J | 2026 | 42497068 | PubTator, text mining | PubMed |
| Simvastatin enhances the antitumor activity of temsirolimus through AMPK-associated metabolic modulation in clear-cell renal cell carcinoma. | Naunyn Schmiedebergs Arch Pharmacol | 2026 | 42493660 | PubTator, text mining | PubMed |
| The baseline vitreous proteome in rhegmatogenous retinal detachment: a case-control study of proliferative vitreoretinopathy. | Sci Rep | 2026 | 42432032 | PubTator, text mining | PubMed |
1 to 10 of 2,174
See all 2,174 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2203
GET https://conductscience.org/api/genes/v1/2203/patents?page=2