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FCER2: Fc epsilon receptor II

1 protein, 84 patents, 1 drug, 5 trials, 2,996 NIH grants and 8,942 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolFCER2HGNC
NameFc epsilon receptor IIHGNC
NCBI Gene ID2208NCBI Gene
HGNC IDHGNC:3612HGNC
EnsemblENSG00000104921NCBI Gene
AliasesBLAST-2, CD23, CD23A, CLEC4J, FCE2, FCErII, FcepsilonRII, IGEBFNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P06734Low affinity immunoglobulin epsilon Fc receptor32123Ensembl, GeneID, HGNCUniProt

Patents 84

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2025163009 A2025-10-2841P06734Espacenet
JP 2025529142 A2025-09-041547P06734Espacenet
JP 2025526827 A2025-08-155P06734Espacenet
US 12371689 B22025-07-291547P06734Espacenet
JP 2025032204 A2025-03-1128316P06734Espacenet
JP 2025032204 A2025-03-1128317P06734Espacenet
EP 4461818 A22024-11-1328316P06734Espacenet
EP 4461818 A22024-11-1328317P06734Espacenet
JP 2024123008 A2024-09-106192P06734Espacenet
JP 2024530467 A2024-08-2141P06734Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
LUMILIXIMABCHEMBL2109151Immunoglobulin epsilon Fc receptor antagonistANTAGONISTChEMBL

Trials 5

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT00801060LUMILIXIMABPHASE2ClinicalTrials.gov
NCT00391066LUMILIXIMABPHASE2ClinicalTrials.gov
NCT00103558LUMILIXIMABPHASE1/PHASE2ClinicalTrials.gov
NCT00058396LUMILIXIMABPHASE1ClinicalTrials.gov
NCT00046488LUMILIXIMABPHASE1ClinicalTrials.gov

NIH grants 2996

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant572,025NIH's project files
P30CA008748Cancer Center Support Grant332,025NIH's project files
ZIASC000550Lymphoma Disease Discovery and Definition212,025NIH's project files
ZIABC011070Hematopathology Diagnosis192,025NIH's project files
ZIEBC011241Hematopathology Fellowship132,025NIH's project files
P30CA016520Abramson Cancer Center Support Grant112,025NIH's project files
P30CA006973Regional Oncology Research Center102,025NIH's project files
P30CA016042Cancer Center Support Grant92,025NIH's project files
ZICSC009372Flow cytometric analysis of benign and malignant tumors92,025NIH's project files
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant82,025NIH's project files

Papers 8942

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42814322PubTator, text miningPubMed
42799816PubTator, text miningPubMed
42776811PubTator, text miningPubMed
42719562PubTator, text miningPubMed
42718563PubTator, text miningPubMed
42709784PubTator, text miningPubMed
42698486PubTator, text miningPubMed
42683405PubTator, text miningPubMed
42661891PubTator, text miningPubMed
42657693PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license