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MARCHF8: membrane associated ring-CH-type finger 8

1 protein, 49 patents, 0 drugs, 0 trials, 1,889 NIH grants and 5,233 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolMARCHF8HGNC
Namemembrane associated ring-CH-type finger 8HGNC
NCBI Gene ID220972NCBI Gene
HGNC IDHGNC:23356HGNC
EnsemblENSG00000165406NCBI Gene
AliasesCMIR, MARCH-VIII, MARCH8, MIR, RNF178, c-MIRNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q5T0T0E3 ubiquitin-protein ligase MARCHF82911Ensembl, GeneID, HGNCUniProt

Patents 49

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1453207Q5T0T0Espacenet
JP 2026004568 A2026-01-1453208Q5T0T0Espacenet
JP 2026004568 A2026-01-1453209Q5T0T0Espacenet
EP 4640849 A22025-10-29712Q5T0T0Espacenet
EP 4641201 A22025-10-294681Q5T0T0Espacenet
JP 2025529142 A2025-09-042548Q5T0T0Espacenet
US 12371689 B22025-07-292548Q5T0T0Espacenet
JP 2025519096 A2025-06-24712Q5T0T0Espacenet
JP 2025517969 A2025-06-124681Q5T0T0Espacenet
JP 2025024198 A2025-02-1913678Q5T0T0Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 1889

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016058Cancer Center Support Grant132,025NIH's project files
P30CA016672Cancer Center Support Grant132,025NIH's project files
R01AI021640Molecular Aspects of Cytomegalovirus Latency92,025NIH's project files
P01AI127335Human Cytomegalovirus dysregulation of host hematopoietic progenitor cell signaling pathways to modulate latency and reactivation82,025NIH's project files
P30CA008748Cancer Center Support Grant52,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant52,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program42,025NIH's project files
P30CA013148Comprehensive Cancer Center Support Grant42,025NIH's project files
P30CA015704Cancer Center Support Grant42,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant42,025NIH's project files

Papers 5233

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42619906PubTator, text miningPubMed
42564586PubTator, text miningPubMed
42544653PubTator, text miningPubMed
42500347PubTator, text miningPubMed
42470818PubTator, text miningPubMed
42464604PubTator, text miningPubMed
42400930PubTator, text miningPubMed
42231335PubTator, text miningPubMed
42151323PubTator, text miningPubMed
42045252PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license