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Gene · 2215

FCGR3B: Fc gamma receptor IIIb

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FCGR3B: Fc gamma receptor IIIb. Genes, record 2215. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2215

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Gene

Symbol
FCGR3B
HGNC
Name
Fc gamma receptor IIIb
HGNC
NCBI Gene ID
2215
NCBI Gene
HGNC ID
HGNC:3620
HGNC
Ensembl
ENSG00000162747
NCBI Gene
Aliases
CD16, CD16-I, CD16b, FCG3, FCGR3, FCRIIIb, FcRIIIb, FcgammaRIIIb, HNA-1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O75015Low affinity immunoglobulin gamma Fc region receptor III-B2336Ensembl, GeneID, HGNC

Source UniProt

Patents62

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026506240 A2026-02-20105O75015Espacenet
JP 2026506241 A2026-02-20105O75015Espacenet
JP 2026004568 A2026-01-1446115O75015Espacenet
JP 2026004568 A2026-01-1446116O75015Espacenet
EP 4650780 A22025-11-198333O75015Espacenet
EP 4641202 A22025-10-29458O75015Espacenet
EP 4641203 A22025-10-29243O75015Espacenet
EP 4585223 A22025-07-1610O75015Espacenet
JP 2025517967 A2025-06-12243O75015Espacenet
JP 2025517970 A2025-06-128333O75015Espacenet

1 to 10 of 62

See all 62 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,380

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFCGR3B papersNewest fiscal year
R01HL065095Regulators of immune complex mediated neutrophil antigen presentation112025
U19AI135995Center for Viral Systems Biology (CViSB)102025
P30AI060354Harvard University Center for AIDS Research92025
P01AI100148Developing Immunogens to Elicit Broadly Neutralizing anti-HIV-1 Antibodies52025
P01CA065493Off-the-Shelf Immune Effector Cells for Hematological Malignancies52025
P01CA111412NK cells, their receptors and cancer therapy52025
P30CA023108Cancer Center Support Grant52025
R01CA203348Expression of recombinant Fc receptors by engineered NK cells to enhance cancer cell killing52025
R35CA196620Molecular mechanisms of antibody-mediated immunotherapies52025
P30CA008748Cancer Center Support Grant42025

1 to 10 of 1,380Source NIH's project files

See all 1,380 nih grants

Papers2,393

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Dynamic inter-glycan interactions regulate site-specific N-glycan maturation in human Fcγ receptor III.Glycobiology202642734298PubTator, text miningPubMed
Acute Myeloid Leukemia(AML) proteins for in silico drug design using pharmacophore modeling, molecular docking and molecular dynamics simulation.PLoS One202642685040PubTator, text miningPubMed
Autoimmune neutropenia in children: Test cells versus beads and a role for pro-LL-37 and absolute neutrophil count.Br J Haematol202642644563PubTator, text miningPubMed
Transcriptome sequencing and validation of potential biomarkers associated with cognitive impairment after hypertensive intracerebral hemorrhage.Front Mol Biosci202642591161PubTator, text miningPubMed
Programmable Nanobody-Targeting Chimeras Enable Intracellular Viral Protein Degradation.Adv Sci (Weinh)202642467897PubTator, text miningPubMed
[A study on HNA-1~-5 genotypes and frequencies in the blood donor population of jiangsu province].Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi202642463312PubTator, text miningPubMed
From Gene Expression to Candidate Biomarkers in Ulcerative Colitis: Aquaporin-9 in Neutrophil Extracellular Traps Formation Pathways.Iran J Med Sci202642370017PubTator, text miningPubMed
EXPLORING POTENTIAL KEY GENES AND MECHANISMS OF PERIODONTITIS THROUGH INTEGRATED BIOINFORMATICS ANALYSIS.Georgian Med News202642289108PubTator, text miningPubMed
Single Cell Transcriptomic Atlas Reveals Cellular Heterogeneity and Molecular Mechanisms in Pediatric Airway Hyperresponsiveness Epithelium.Int J Genomics202642273288PubTator, text miningPubMed
Neutrophil FcγRI expression as a determinant of oxidative responses in human blood.J Leukoc Biol202641983306PubTator, text miningPubMed

1 to 10 of 2,393

See all 2,393 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2215

GET https://conductscience.org/api/genes/v1/2215/patents?page=2