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Gene · 2217

FCGRT: Fc gamma receptor and transporter

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. FCGRT: Fc gamma receptor and transporter. Genes, record 2217. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/2217

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
FCGRT
HGNC
Name
Fc gamma receptor and transporter
HGNC
NCBI Gene ID
2217
NCBI Gene
HGNC ID
HGNC:3621
HGNC
Ensembl
ENSG00000104870
NCBI Gene
Aliases
FCRN, FcRn, FcgammaRn, alpha-chain
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P55899IgG receptor FcRn large subunit p5136532Ensembl, GeneID, HGNC

Source UniProt

Patents349

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4810511 A12026-09-231P55899Espacenet
JP 2026139478 A2026-09-011P55899Espacenet
WO 2026168474 A2026-08-131P55899Espacenet
US 12662526 B22026-06-2381P55899Espacenet
JP 2026098029 A2026-06-1646P55899Espacenet
EP 4755457 A22026-06-10179P55899Espacenet
JP 2026094161 A2026-06-0917P55899Espacenet
JP 2026088609 A2026-05-293P55899Espacenet
EP 4744681 A12026-05-2013P55899Espacenet
EP 4744728 A22026-05-2081P55899Espacenet

1 to 10 of 349

See all 349 patents

Drugs5

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
BATOCLIMABCHEMBL4650514IgG receptor FcRn large subunit p51 inhibitorINHIBITORChEMBL
EFGARTIGIMOD ALFACHEMBL4297551IgG receptor FcRn large subunit p51 antagonistANTAGONISTChEMBL
NIPOCALIMABCHEMBL4594310IgG receptor FcRn large subunit p51 antagonistANTAGONISTChEMBL
ORILANOLIMABCHEMBL4298117IgG receptor FcRn large subunit p51 antagonistANTAGONISTChEMBL
ROZANOLIXIZUMABCHEMBL4297820IgG receptor FcRn large subunit p51 inhibitorINHIBITORChEMBL

Trials112

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07596849EFGARTIGIMOD ALFAPHASE3ClinicalTrials.gov
NCT07583641EFGARTIGIMOD ALFAPHASE2ClinicalTrials.gov
NCT07570316EFGARTIGIMOD ALFAPHASE3ClinicalTrials.gov
NCT07438496NIPOCALIMABPHASE3ClinicalTrials.gov
NCT07294170EFGARTIGIMOD ALFAClinicalTrials.gov
NCT07264426EFGARTIGIMOD ALFAClinicalTrials.gov
NCT07246564ROZANOLIXIZUMABPHASE4ClinicalTrials.gov
NCT07231523EFGARTIGIMOD ALFAPHASE3ClinicalTrials.gov
NCT07217587EFGARTIGIMOD ALFAPHASE3ClinicalTrials.gov
NCT07217587NIPOCALIMABPHASE3ClinicalTrials.gov

1 to 10 of 112

See all 112 trials

NIH grants1,970

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30DK034854Integrated Epithelial and Muscosal Biology372025
R01DK044319Characterization of Mucosal Lymphocytes222025
P30CA008748Cancer Center Support Grant182025
R01DK051362Regulation of Mucosal Lymphocytes182025
P30CA016042Cancer Center Support Grant142025
R01DK088199Endoplasmic reticulum stress and intestinal inflammation122025
P30CA034196Cancer Center Support (CORE) Grant92025
P51OD011132Emory National Primate Research Center92025
ZIAAI005022Antibody Neutralization Mechanisms92025
P51OD011092Support for National Primate Research Center82025

1 to 10 of 1,970Source NIH's project files

See all 1,970 nih grants

Papers4,523

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42817104PubTator, text miningPubMed
42814271PubTator, text miningPubMed
42813052PubTator, text miningPubMed
42807841PubTator, text miningPubMed
42797515PubTator, text miningPubMed
42788065PubTator, text miningPubMed
42786373PubTator, text miningPubMed
42782276PubTator, text miningPubMed
42778652PubTator, text miningPubMed
42772286PubTator, text miningPubMed

1 to 10 of 4,523

See all 4,523 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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