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Gene · 2219

FCN1: ficolin 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FCN1: ficolin 1. Genes, record 2219. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2219

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Gene

Symbol
FCN1
HGNC
Name
ficolin 1
HGNC
NCBI Gene ID
2219
NCBI Gene
HGNC ID
HGNC:3623
HGNC
Ensembl
ENSG00000085265
NCBI Gene
Aliases
FCNM
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O00602Ficolin-13267Ensembl, GeneID, HGNC

Source UniProt

Patents61

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1446326O00602Espacenet
WO 2025262255 A12025-12-269O00602Espacenet
EP 4650780 A22025-11-199012O00602Espacenet
JP 2025147176 A2025-10-065222O00602Espacenet
JP 2025529142 A2025-09-041556O00602Espacenet
JP 2025529142 A2025-09-046356O00602Espacenet
US 12371689 B22025-07-291556O00602Espacenet
US 12371689 B22025-07-296356O00602Espacenet
JP 2025517970 A2025-06-129012O00602Espacenet
JP 2025028160 A2025-02-285222O00602Espacenet

1 to 10 of 61

See all 61 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants728

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFCN1 papersNewest fiscal year
R01AR051749Complement in the Pathogenesis of Autoimmune Arthritis52025
P01HL136275Immune Cell Interactions in Atherosclerosis42025
P30CA016042Cancer Center Support Grant42025
P30CA008748Cancer Center Support Grant32025
P50CA211015UCLA SPORE in Brain Cancer32025
T32CA009120UCLA Tumor Immunology Institutional Training Grant32025
T32HG002295Training in Bioinformatics and Integrative Genomics32025
UL1TR001881UCLA Clinical and Translational Science Institute32025
IK2BX005875The Tumor Immune Microenvironment in Pancreatic Cancer Chemoresistance22025
K08AR077689Epidermal Growth Factor Receptor Signaling in Fibrotic Skin Disease22025

1 to 10 of 728Source NIH's project files

See all 728 nih grants

Papers1,425

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Complement expression profiles in human glomerular mesangial cells, endothelial cells, podocytes and proximal tubular epithelial cells.Front Immunol202642746023PubTator, text miningPubMed
T-follicular helper cell communication with myeloid compartments plays a key role in the inflammatory response in localized scleroderma: Insights from skin single-cell RNA sequencing.J Invest Dermatol202642716215PubTator, text miningPubMed
RUNX3+ basal-like malignant cells: architects of an immunosuppressive microenvironment in bladder cancer: a comprehensive bioinformatics analysis of single-cell and spatial transcriptomics.Int J Surg202642682391PubTator, text miningPubMed
Unveiling the Cellular and Molecular Insights into Ulcerative Colitis Pathogenesis through Integrative Multi-omics and Functional Experiments.Comb Chem High Throughput Screen202642393888PubTator, text miningPubMed
Machine learning algorithms develop a tumor-educated platelets-related gene signature to predict colorectal cancer prognosis and therapy response.iScience202642375537PubTator, text miningPubMed
Mass Spectrometry-Driven Proteomic Biomarkers for Serum-Based Detection of Pancreatic Ductal Adenocarcinoma and Intraductal Papillary Mucinous Neoplasm-Associated Invasive Carcinoma.Cancer Med202642136141PubTator, text miningPubMed
Tumor-Infiltrating mregDCs Restrain Anti-Tumor Immunity in Early Relapse HCC.Adv Sci (Weinh)202642133204PubTator, text miningPubMed
Proteomic Profiling of Human Extracellular Vesicles Reveals Diagnostic Biomarkers for Colon Adenocarcinoma.J Extracell Vesicles202641979056PubTator, text miningPubMed
Mass cytometry uncovers distinct blood myeloid phenotypes linked to clinical responses during gastric cancer chemoimmunotherapy.Cancer Immunol Immunother202641915048PubTator, text miningPubMed
In-Depth Multi-Assembler Venom-Gland Transcriptomics of Three Medically Important Colombian Snakes Highlights Diversity of Accessory, Low-Abundance Protein Families.Toxins (Basel)202641893541PubTator, text miningPubMed

1 to 10 of 1,425

See all 1,425 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2219

GET https://conductscience.org/api/genes/v1/2219/patents?page=2