Gene · 2219
FCN1: ficolin 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. FCN1: ficolin 1. Genes, record 2219. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2219
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O00602 | Ficolin-1 | 326 | 7 | Ensembl, GeneID, HGNC |
Source UniProt
Patents61
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 46326 | O00602 | Espacenet |
| WO 2025262255 A1 | 2025-12-26 | 9 | O00602 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 9012 | O00602 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 5222 | O00602 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1556 | O00602 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6356 | O00602 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1556 | O00602 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6356 | O00602 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 9012 | O00602 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 5222 | O00602 | Espacenet |
1 to 10 of 61
See all 61 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants728
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | FCN1 papers | Newest fiscal year |
|---|---|---|---|
| R01AR051749 | Complement in the Pathogenesis of Autoimmune Arthritis | 5 | 2025 |
| P01HL136275 | Immune Cell Interactions in Atherosclerosis | 4 | 2025 |
| P30CA016042 | Cancer Center Support Grant | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P50CA211015 | UCLA SPORE in Brain Cancer | 3 | 2025 |
| T32CA009120 | UCLA Tumor Immunology Institutional Training Grant | 3 | 2025 |
| T32HG002295 | Training in Bioinformatics and Integrative Genomics | 3 | 2025 |
| UL1TR001881 | UCLA Clinical and Translational Science Institute | 3 | 2025 |
| IK2BX005875 | The Tumor Immune Microenvironment in Pancreatic Cancer Chemoresistance | 2 | 2025 |
| K08AR077689 | Epidermal Growth Factor Receptor Signaling in Fibrotic Skin Disease | 2 | 2025 |
1 to 10 of 728Source NIH's project files
See all 728 nih grantsPapers1,425
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Complement expression profiles in human glomerular mesangial cells, endothelial cells, podocytes and proximal tubular epithelial cells. | Front Immunol | 2026 | 42746023 | PubTator, text mining | PubMed |
| T-follicular helper cell communication with myeloid compartments plays a key role in the inflammatory response in localized scleroderma: Insights from skin single-cell RNA sequencing. | J Invest Dermatol | 2026 | 42716215 | PubTator, text mining | PubMed |
| RUNX3+ basal-like malignant cells: architects of an immunosuppressive microenvironment in bladder cancer: a comprehensive bioinformatics analysis of single-cell and spatial transcriptomics. | Int J Surg | 2026 | 42682391 | PubTator, text mining | PubMed |
| Unveiling the Cellular and Molecular Insights into Ulcerative Colitis Pathogenesis through Integrative Multi-omics and Functional Experiments. | Comb Chem High Throughput Screen | 2026 | 42393888 | PubTator, text mining | PubMed |
| Machine learning algorithms develop a tumor-educated platelets-related gene signature to predict colorectal cancer prognosis and therapy response. | iScience | 2026 | 42375537 | PubTator, text mining | PubMed |
| Mass Spectrometry-Driven Proteomic Biomarkers for Serum-Based Detection of Pancreatic Ductal Adenocarcinoma and Intraductal Papillary Mucinous Neoplasm-Associated Invasive Carcinoma. | Cancer Med | 2026 | 42136141 | PubTator, text mining | PubMed |
| Tumor-Infiltrating mregDCs Restrain Anti-Tumor Immunity in Early Relapse HCC. | Adv Sci (Weinh) | 2026 | 42133204 | PubTator, text mining | PubMed |
| Proteomic Profiling of Human Extracellular Vesicles Reveals Diagnostic Biomarkers for Colon Adenocarcinoma. | J Extracell Vesicles | 2026 | 41979056 | PubTator, text mining | PubMed |
| Mass cytometry uncovers distinct blood myeloid phenotypes linked to clinical responses during gastric cancer chemoimmunotherapy. | Cancer Immunol Immunother | 2026 | 41915048 | PubTator, text mining | PubMed |
| In-Depth Multi-Assembler Venom-Gland Transcriptomics of Three Medically Important Colombian Snakes Highlights Diversity of Accessory, Low-Abundance Protein Families. | Toxins (Basel) | 2026 | 41893541 | PubTator, text mining | PubMed |
1 to 10 of 1,425
See all 1,425 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2219
GET https://conductscience.org/api/genes/v1/2219/patents?page=2