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FDFT1: farnesyl-diphosphate farnesyltransferase 1
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Gene · 2222

Papers2,006

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 2,006

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TitleJournalYearPMIDFound bySource
FDFT1 is associated with ovarian reserve and regulates proliferation and steroidogenesis in the human granulosa cell line KGN via the AKT/mTOR signaling pathway.J Steroid Biochem Mol Biol202742705556PubTator, text miningPubMed
Combined Analysis of Metabolome and Transcriptome Reveals Bauhinia variegata-Specific Floral Scent Profile and Key Aroma Components.Metabolites202642783736PubTator, text miningPubMed
Gypenosides Damulin A and Damulin B Inhibit Hepatocellular Carcinoma by Regulating Cholesterol Synthesis.Drug Dev Res202642750477PubTator, text miningPubMed
GhSQS1-mediated squalene accumulation coordinates cotton development and stress resilience.J Exp Bot202642717800PubTator, text miningPubMed
Postzygotic biallelic inactivation of FDFT1 underlies solitary lesion formation in porokeratosis of Mibelli.J Dermatol Sci202642716848PubTator, text miningPubMed
Brusatol Triggers Cell Cycle Arrest and Apoptosis, Disrupts Sterol Biosynthesis, and Enhances the Anti-Leukemic Activity of Venetoclax in AML Cells.Cell Biochem Biophys202642711651PubTator, text miningPubMed
Enantioselective Total Synthesis of (+)-Bisabosqual A and Studies on Late-Stage C(sp3)-H Functionalization Approaches to Bisabosquals.J Org Chem202642681704PubTator, text miningPubMed
Genetic associations and candidate functional genes linking depression and obesity: a multi-omics integrative study.Front Genet202642626419PubTator, text miningPubMed
Construction and validation of a nomogram for the diagnosis of postmenopausal osteoporosis.Mol Med Rep202642596822PubTator, text miningPubMed
Cholesterol metabolic rewiring shapes immune remodeling across hepatocarcinogenesis.Front Immunol202642488674PubTator, text miningPubMed
Β-Sitosterol-imidazolium ionic liquid conjugates: synthesis, computational evaluation, and anticancer activity against colorectal cancer cells.Steroids202642486216PubTator, text miningPubMed
Fisetin prevents deterioration of cellular functions in amyotrophic lateral sclerosis variants G262R and P438L of SQSTM1 in SH-SY5Y cells.Toxicol Appl Pharmacol202642431556PubTator, text miningPubMed
Corrigendum to: Impact of HIV-1 Tat on FDFT1 Suppression, Changes in Cholesterol Level, and KSHV Replication in BCBL1 Cells.Curr HIV Res202642370517PubTator, text miningPubMed
Overexpression of the ATP-Citrate Lyase Gene Enhances Ganoderic Acid Biosynthesis in Ganoderma lingzhi.Mol Biotechnol202642350876PubTator, text miningPubMed
Genomic relationship between polyendocrine metabolic ovarian syndrome and bipolar disorder.Eur Neuropsychopharmacol202642349268PubTator, text miningPubMed
Diverse clinical manifestations of porokeratosis caused by somatic variants and promoter hypermethylation of FDFT1.Br J Dermatol202642312625PubTator, text miningPubMed
Single-cell multi-omics dissection of RevitalAge Markers uncovers age-dependent immunotherapy resistance and druggable targets in melanoma.Biol Direct202642304383PubTator, text miningPubMed
FDFT1 Suppresses Ovarian Tumorigenesis and Overcomes Cisplatin Resistance by Activating Ferroptosis Through the NRF2/GPX4/SLC7A11 Axis.Curr Cancer Drug Targets202642300311PubTator, text miningPubMed
A human corticospinal organoid-slice connectoid model informs enhancer strategies for post-injury axon regrowth.Cell Rep202642201810PubTator, text miningPubMed
Total and engineered biosynthesis of cinatrins: inhibitors of phospholipase A2 and squalene synthase.Chem Sci202642146794PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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