Gene · 2230
FDX1: ferredoxin 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. FDX1: ferredoxin 1. Genes, record 2230. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2230
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P10109 | Adrenodoxin, mitochondrial | 184 | 6 | Ensembl, GeneID, HGNC |
Source UniProt
Patents40
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026082924 A | 2026-05-19 | 6 | P10109 | Espacenet |
| US 12545918 B2 | 2026-02-10 | 8 | P10109 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 46167 | P10109 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 1792 | P10109 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 1792 | P10109 | Espacenet |
| JP 2023515302 A | 2023-04-13 | 7 | P10109 | Espacenet |
| US 11612619 B2 | 2023-03-28 | 8 | P10109 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 31639 | P10109 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 134610 | P10109 | Espacenet |
| WO 2021174100 A1 | 2021-09-02 | 6 | P10109 | Espacenet |
1 to 10 of 40
See all 40 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants420
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | FDX1 papers | Newest fiscal year |
|---|---|---|---|
| ZIAHD008814 | Mammalian iron-sulfur cluster biogenesis | 6 | 2025 |
| R01GM086596 | Activation of androgen biosynthesis and drug metabolism by cytochrome b5 | 5 | 2025 |
| R35GM133375 | Structural regulation of Class-I and Class-II cytochrome P450 enzymes | 5 | 2025 |
| R35GM122595 | Mechanisms of Iron-Sulfur Dependent Reactions | 4 | 2025 |
| P30CA093373 | Cancer Center Support Grant P30 | 3 | 2025 |
| R35CA242457 | Making cancer precision medicine real: bottlenecks and opportunities | 3 | 2025 |
| T32ES007028 | Training Program in Environmental Toxicology | 3 | 2025 |
| ZIAHD001602 | Regulation Of Intracellular Iron Metabolism | 3 | 2025 |
| P20GM103434 | West Virginia IDeA Network of Biomedical Research Excellence (WV-INBRE) | 2 | 2025 |
| P20GM121322 | Tumor Microenvironment-TME CoBRE | 2 | 2025 |
1 to 10 of 420Source NIH's project files
See all 420 nih grantsPapers1,417
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| SUMOylation of PGAM2 regulates mitochondrial metabolism and cuproptosis-related damage during boar sperm cryoinjury. | Theriogenology | 2027 | 42810240 | PubTator, text mining | PubMed |
| FDX1-short proteoform induces caspase-independent cell death in tumor cells. | Cell Death Differ | 2026 | 42816659 | PubTator, text mining | PubMed |
| Roles of cuproptosis in central nervous system tumors: from molecular mechanisms to therapeutic prospects. | Front Cell Dev Biol | 2026 | 42812787 | PubTator, text mining | PubMed |
| Targeting FDX1 with oridonin triggers cuproptosis and inhibits tumor progression in nasopharyngeal carcinoma. | Int J Biochem Cell Biol | 2026 | 42800577 | PubTator, text mining | PubMed |
| Copper-regulated cell death after spinal cord injury: evidence boundaries for non-coding RNA, epigenetics and cuproptosis. | Front Mol Neurosci | 2026 | 42787557 | PubTator, text mining | PubMed |
| Cuproptosis: a novel mechanism linking placental metabolic stress to trophoblast injury in preeclampsia. | Front Endocrinol (Lausanne) | 2026 | 42780476 | PubTator, text mining | PubMed |
Elesclomol-mediated cuproptosis overcomes cisplatin resistance by restricting epigenetically activated mitochondrial respiration: Novel therapeutic insights into cisplatin-elesclomol combination therapy. | Acta Pharm Sin B | 2026 | 42764935 | PubTator, text mining | PubMed |
| SF1 regulates the transcription of FDX1 to promote cuproptosis in pediatric sepsis-related acute lung injury by interacting with cJUN. | Biol Direct | 2026 | 42764381 | PubTator, text mining | PubMed |
| SOX2 Inhibits Cuproptosis to Affect Cisplatin Resistance in Non-Small Cell Lung Cancer by Activating the Wnt/ATP7B Signaling Pathway. | Kaohsiung J Med Sci | 2026 | 42757550 | PubTator, text mining | PubMed |
| Cuproptosis in cerebrovascular diseases: Mechanisms and advances in targeted therapeutic strategies. | Brain Res Bull | 2026 | 42754178 | PubTator, text mining | PubMed |
1 to 10 of 1,417
See all 1,417 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2230
GET https://conductscience.org/api/genes/v1/2230/patents?page=2