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Gene · 2232

FDXR: ferredoxin reductase

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FDXR: ferredoxin reductase. Genes, record 2232. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2232

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Gene

Symbol
FDXR
HGNC
Name
ferredoxin reductase
HGNC
NCBI Gene ID
2232
NCBI Gene
HGNC ID
HGNC:3642
HGNC
Ensembl
ENSG00000161513
NCBI Gene
Aliases
ADR, ADXR, ANOA, AR, MMDS9B
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P22570NADPH:adrenodoxin oxidoreductase, mitochondrial4910Ensembl, GeneID, HGNC

Source UniProt

Patents14

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026082924 A2026-05-195P22570Espacenet
US 12545918 B22026-02-107P22570Espacenet
JP 2023515302 A2023-04-136P22570Espacenet
US 11612619 B22023-03-287P22570Espacenet
WO 2021174100 A12021-09-025P22570Espacenet
US 10947596 B22021-03-1654P22570Espacenet
JP 2014524015 A2014-09-1841P22570Espacenet
WO 2013190075 A22013-12-27871P22570Espacenet
WO 2012172370 A12012-12-2041P22570Espacenet
US 7998689 B22011-08-161477P22570Espacenet

1 to 10 of 14

See all 14 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants876

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFDXR papersNewest fiscal year
R01AI021150Gonococci: Genetics of Resistance to PMN Proteins112025
P30CA016672Cancer Center Support Grant82025
ZIAHD008814Mammalian iron-sulfur cluster biogenesis82025
P30CA093373Cancer Center Support Grant P3062025
P30ES010126UNC Center for Environmental Health and Susceptibility62025
R01DK045776B12 Trafficking and Inherited Defects62025
R01GM086596Activation of androgen biosynthesis and drug metabolism by cytochrome b552025
R35GM133375Structural regulation of Class-I and Class-II cytochrome P450 enzymes52025
ZIAHD001602Regulation Of Intracellular Iron Metabolism52025
P30ES013508Center of Excellence in Environmental Toxicology42025

1 to 10 of 876Source NIH's project files

See all 876 nih grants

Papers2,659

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A comprehensive meta-analysis on the impact of airborne particulate matter on trophoblast/placental vessel related cell function In Vitro.Reprod Toxicol202642772605PubTator, text miningPubMed
Structural and Functional Impact of the G340S Mutation in Plasmodium falciparum Ferredoxin NADP⁺ Reductase: In silico Analysis and Molecular Docking.Gates Open Res202642723717PubTator, text miningPubMed
Copper, cuproptosis, and cancer: biology concepts of a novel cell death.Apoptosis202642693224PubTator, text miningPubMed
Accurate estimation of clinically significant radiation doses up to 5 Gy using qRT-PCR based gene expression analysis.Int J Radiat Biol202642671271PubTator, text miningPubMed
The Role of Cytochrome P450 Holoenzyme Metabolism in the Origin of Neuropathologies.Int J Mol Sci202642589625PubTator, text miningPubMed
Correlation of a four gene set with H-ARS severity in irradiated minipigs treated with Myelo001.Int J Radiat Biol202642566227PubTator, text miningPubMed
Neuroimaging in FDXR-related mitochondriopathy.Pediatr Radiol202642484718PubTator, text miningPubMed
Free Radical Formation in the Reactions of Redox-Active Drugs and Xenobiotics with Mitochondrial Flavoenzymes.Biomolecules202642352277PubTator, text miningPubMed
Characterization of Radiation-responsive Genes and Transcript Variants under Different Radiation Qualities, Doses and Dose Rates.Radiat Res202642307549PubTator, text miningPubMed
Salivary Gene Expression Changes after Total Body Irradiation in Leukemia Patients: Toward Non-invasive Biodosimetry.Radiat Res202642235939PubTator, text miningPubMed

1 to 10 of 2,659

See all 2,659 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2232

GET https://conductscience.org/api/genes/v1/2232/patents