Gene · 2232
FDXR: ferredoxin reductase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. FDXR: ferredoxin reductase. Genes, record 2232. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2232
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P22570 | NADPH:adrenodoxin oxidoreductase, mitochondrial | 491 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents14
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026082924 A | 2026-05-19 | 5 | P22570 | Espacenet |
| US 12545918 B2 | 2026-02-10 | 7 | P22570 | Espacenet |
| JP 2023515302 A | 2023-04-13 | 6 | P22570 | Espacenet |
| US 11612619 B2 | 2023-03-28 | 7 | P22570 | Espacenet |
| WO 2021174100 A1 | 2021-09-02 | 5 | P22570 | Espacenet |
| US 10947596 B2 | 2021-03-16 | 54 | P22570 | Espacenet |
| JP 2014524015 A | 2014-09-18 | 41 | P22570 | Espacenet |
| WO 2013190075 A2 | 2013-12-27 | 871 | P22570 | Espacenet |
| WO 2012172370 A1 | 2012-12-20 | 41 | P22570 | Espacenet |
| US 7998689 B2 | 2011-08-16 | 1477 | P22570 | Espacenet |
1 to 10 of 14
See all 14 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants876
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | FDXR papers | Newest fiscal year |
|---|---|---|---|
| R01AI021150 | Gonococci: Genetics of Resistance to PMN Proteins | 11 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 8 | 2025 |
| ZIAHD008814 | Mammalian iron-sulfur cluster biogenesis | 8 | 2025 |
| P30CA093373 | Cancer Center Support Grant P30 | 6 | 2025 |
| P30ES010126 | UNC Center for Environmental Health and Susceptibility | 6 | 2025 |
| R01DK045776 | B12 Trafficking and Inherited Defects | 6 | 2025 |
| R01GM086596 | Activation of androgen biosynthesis and drug metabolism by cytochrome b5 | 5 | 2025 |
| R35GM133375 | Structural regulation of Class-I and Class-II cytochrome P450 enzymes | 5 | 2025 |
| ZIAHD001602 | Regulation Of Intracellular Iron Metabolism | 5 | 2025 |
| P30ES013508 | Center of Excellence in Environmental Toxicology | 4 | 2025 |
1 to 10 of 876Source NIH's project files
See all 876 nih grantsPapers2,659
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A comprehensive meta-analysis on the impact of airborne particulate matter on trophoblast/placental vessel related cell function In Vitro. | Reprod Toxicol | 2026 | 42772605 | PubTator, text mining | PubMed |
| Structural and Functional Impact of the G340S Mutation in Plasmodium falciparum Ferredoxin NADP⁺ Reductase: In silico Analysis and Molecular Docking. | Gates Open Res | 2026 | 42723717 | PubTator, text mining | PubMed |
| Copper, cuproptosis, and cancer: biology concepts of a novel cell death. | Apoptosis | 2026 | 42693224 | PubTator, text mining | PubMed |
| Accurate estimation of clinically significant radiation doses up to 5 Gy using qRT-PCR based gene expression analysis. | Int J Radiat Biol | 2026 | 42671271 | PubTator, text mining | PubMed |
| The Role of Cytochrome P450 Holoenzyme Metabolism in the Origin of Neuropathologies. | Int J Mol Sci | 2026 | 42589625 | PubTator, text mining | PubMed |
| Correlation of a four gene set with H-ARS severity in irradiated minipigs treated with Myelo001. | Int J Radiat Biol | 2026 | 42566227 | PubTator, text mining | PubMed |
| Neuroimaging in FDXR-related mitochondriopathy. | Pediatr Radiol | 2026 | 42484718 | PubTator, text mining | PubMed |
| Free Radical Formation in the Reactions of Redox-Active Drugs and Xenobiotics with Mitochondrial Flavoenzymes. | Biomolecules | 2026 | 42352277 | PubTator, text mining | PubMed |
| Characterization of Radiation-responsive Genes and Transcript Variants under Different Radiation Qualities, Doses and Dose Rates. | Radiat Res | 2026 | 42307549 | PubTator, text mining | PubMed |
| Salivary Gene Expression Changes after Total Body Irradiation in Leukemia Patients: Toward Non-invasive Biodosimetry. | Radiat Res | 2026 | 42235939 | PubTator, text mining | PubMed |
1 to 10 of 2,659
See all 2,659 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2232
GET https://conductscience.org/api/genes/v1/2232/patents