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FGF2: fibroblast growth factor 2

1 protein, 249 patents, 1 drug, 9 trials, 18,758 NIH grants and 53,070 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolFGF2HGNC
Namefibroblast growth factor 2HGNC
NCBI Gene ID2247NCBI Gene
HGNC IDHGNC:3676HGNC
EnsemblENSG00000138685NCBI Gene
AliasesBFGF, FGF-2, FGFB, HBGF-2NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P09038Fibroblast growth factor 228825Ensembl, GeneID, HGNCUniProt

Patents 249

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026048907 A2026-03-178P09038Espacenet
EP 4705273 A22026-03-11210P09038Espacenet
JP 2026034588 A2026-02-2718P09038Espacenet
WO 2026027990 A12026-02-054P09038Espacenet
JP 2026004467 A2026-01-1418P09038Espacenet
EP 4640838 A12025-10-298P09038Espacenet
WO 2025219552 A12025-10-232P09038Espacenet
JP 2025531671 A2025-09-2560P09038Espacenet
EP 4606428 A22025-08-2712P09038Espacenet
JP 2025105692 A2025-07-107P09038Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
MUPARFOSTATCHEMBL4297163Basic fibroblast growth factor inhibitorINHIBITORChEMBL

Trials 9

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT01402908MUPARFOSTATPHASE32020-12-30ClinicalTrials.gov
NCT00568308MUPARFOSTATPHASE3ClinicalTrials.gov
NCT00268593MUPARFOSTATPHASE2ClinicalTrials.gov
NCT00247728MUPARFOSTATPHASE22020-11-12ClinicalTrials.gov
NCT00130442MUPARFOSTATPHASE22021-01-22ClinicalTrials.gov
NCT00103389MUPARFOSTATPHASE2ClinicalTrials.gov
NCT00097851MUPARFOSTATPHASE2ClinicalTrials.gov
NCT00073892MUPARFOSTATPHASE1/PHASE2ClinicalTrials.gov
NCT00068172MUPARFOSTATPHASE1/PHASE2ClinicalTrials.gov

NIH grants 18758

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant2062,025NIH's project files
P30CA008748Cancer Center Support Grant1362,025NIH's project files
P30CA016058Cancer Center Support Grant452,025NIH's project files
P30CA014520UW Comprehensive Cancer Center Support442,025NIH's project files
P30CA014195Cancer Center Support Grant (CCSG)382,025NIH's project files
P30CA006973Regional Oncology Research Center362,025NIH's project files
P30CA060553The Robert H. Lurie Comprehensive Cancer Center362,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award362,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant342,025NIH's project files
P30CA047904Cancer Center Support Grant342,025NIH's project files

Papers 53070

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42823612PubTator, text miningPubMed
42811969PubTator, text miningPubMed
42804095PubTator, text miningPubMed
42801572PubTator, text miningPubMed
42793985PubTator, text miningPubMed
42785546PubTator, text miningPubMed
42781773PubTator, text miningPubMed
42780575PubTator, text miningPubMed
42778431PubTator, text miningPubMed
42778113PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license