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Gene · 2249

FGF4: fibroblast growth factor 4

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FGF4: fibroblast growth factor 4. Genes, record 2249. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2249

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Gene

Symbol
FGF4
HGNC
Name
fibroblast growth factor 4
HGNC
NCBI Gene ID
2249
NCBI Gene
HGNC ID
HGNC:3682
HGNC
Ensembl
ENSG00000075388
NCBI Gene
Aliases
FGF-4, HBGF-4, HST, HST-1, HSTF-1, HSTF1, K-FGF, KFGF, SRTD22
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P08620Fibroblast growth factor 42061Ensembl, GeneID, HGNC

Source UniProt

Patents165

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4705273 A22026-03-11212P08620Espacenet
EP 4650780 A22025-11-19137P08620Espacenet
JP 2025147176 A2025-10-065283P08620Espacenet
JP 2025529142 A2025-09-046376P08620Espacenet
EP 4606428 A22025-08-2743P08620Espacenet
US 12371689 B22025-07-296376P08620Espacenet
JP 2025517970 A2025-06-12137P08620Espacenet
JP 2025509296 A2025-04-1194P08620Espacenet
JP 2025028160 A2025-02-285283P08620Espacenet
JP 2025013347 A2025-01-24212P08620Espacenet

1 to 10 of 165

See all 165 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,054

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFGF4 papersNewest fiscal year
P30CA008748Cancer Center Support Grant312025
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease302025
P30CA016672Cancer Center Support Grant262025
P30CA036727Buffett Cancer Center Support Grant182025
P01HD093363CLEAR Consortium: Discovering the Developmental Mechanisms of Trachea-Esophageal Birth Defects72025
T32CA009476Cancer Biology Training Program72025
P30EY016665Core Grant for Vision Research62025
UL1TR001863Yale Clinical and Translational Science Award62025
P30CA044579University of Virginia Cancer Center Support Grant52025
P30CA068485Cancer Center Support Grant52025

1 to 10 of 2,054Source NIH's project files

See all 2,054 nih grants

Papers3,660

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
FGF4 sustained-release nano-liposomes attenuate heat stroke-induced MODS by suppressing ZBP1-mediated programmed necrosis.Int Immunopharmacol202642805119PubTator, text miningPubMed
An Accessible Approach to Molecular and Biomarker Testing for Risk Stratification in Oral Cavity Squamous Cell Carcinoma.Head Neck Pathol202642758366PubTator, text miningPubMed
Reconstruction and metabolic regulation of O-succinyl-L-homoserine biosynthesis pathway in Escherichia coli W3110.J Biotechnol202642686028PubTator, text miningPubMed
Synthetic Heparan Sulfate-like Oligosaccharides as Tools to Decipher Growth Factor Recognition.J Med Chem202642681846PubTator, text miningPubMed
Genotypic Distribution of FGF4L2 in DTK-Registered Dachshunds in Germany: A Pilot Study.Genes (Basel)202642650162PubTator, text miningPubMed
A Mechanistic Review of Environmental Stressor to Decode Their Effect on Congenital Malformations: A Developmental Toxicity.J Biochem Mol Toxicol202642573050PubTator, text miningPubMed
Demographic Factors Affect the BMAC Proteome.J Proteome Res202642565727PubTator, text miningPubMed
Genomic Characterization of Urothelial Carcinoma and Sarcomatoid Carcinoma of the Upper Urinary Tract.Cancers (Basel)202642512413PubTator, text miningPubMed
Clinicopathologic and molecular characteristics of acral melanomas harboring RARA fusions.Hum Pathol202642398544PubTator, text miningPubMed
In vitro generation of human embryonic stem cell-derived heart organoids possessing physiological ion currents.Regen Ther202642395059PubTator, text miningPubMed

1 to 10 of 3,660

See all 3,660 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2249

GET https://conductscience.org/api/genes/v1/2249/patents?page=2