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Gene · 2250

FGF5: fibroblast growth factor 5

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. FGF5: fibroblast growth factor 5. Genes, record 2250. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2250

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Gene

Symbol
FGF5
HGNC
Name
fibroblast growth factor 5
HGNC
NCBI Gene ID
2250
NCBI Gene
HGNC ID
HGNC:3683
HGNC
Ensembl
ENSG00000138675
NCBI Gene
Aliases
HBGF-5, Smag-82, TCMGLY
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P12034Fibroblast growth factor 52680Ensembl, GeneID, HGNC

Source UniProt

Patents87

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4705273 A22026-03-11213P12034Espacenet
EP 4650780 A22025-11-194774P12034Espacenet
JP 2025147176 A2025-10-065285P12034Espacenet
EP 4624488 A12025-10-013P12034Espacenet
EP 4624488 A12025-10-018P12034Espacenet
JP 2025529142 A2025-09-046377P12034Espacenet
US 12371689 B22025-07-296377P12034Espacenet
JP 2025517970 A2025-06-124774P12034Espacenet
JP 2025032204 A2025-03-1128384P12034Espacenet
JP 2025028160 A2025-02-285285P12034Espacenet

1 to 10 of 87

See all 87 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,167

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleFGF5 papersNewest fiscal year
P30CA008748Cancer Center Support Grant72025
P30ES010126UNC Center for Environmental Health and Susceptibility62025
P30DK063491Diabetes Research Center (DRC)52025
R01HL086694From GWAS loci to blood pressure genes, variants & mechanisms - Renewal52025
P30CA016672Cancer Center Support Grant42025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant32025
P30DK084567Mayo Center for Cell Signaling in Gastroenterology32025
R01AR047364Epigenetic Regulation of Skin Regional Specificity32025
R01DK062370Identifying Genes for Type 2 Diabetes: FUSION32025
ZIAHG000024Genetic analysis of type II diabetes32025

1 to 10 of 1,167Source NIH's project files

See all 1,167 nih grants

Papers1,455

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Genetically Predicted Gut Microbial Taxa and Inflammatory Proteins Associated With Atrial Fibrillation: A Bidirectional Mendelian Randomization and Colocalization Study.J Arrhythm202642798960PubTator, text miningPubMed
Evaluating the pathogenic significance of unique chromosomal variants in craniosynostosis using patient-derived induced pluripotent stem cells and mouse modeling.Genet Med202642708327PubTator, text miningPubMed
FGF5 promotes catagen induction through upregulation of TGF-β2 in human dermal papilla cells.Biochem Biophys Res Commun202642612390PubTator, text miningPubMed
Plasma Proteins Associated With Incident Acute Myocardial Infarction in Asians With Type 2 Diabetes.JACC Asia202642584388PubTator, text miningPubMed
A Mechanistic Review of Environmental Stressor to Decode Their Effect on Congenital Malformations: A Developmental Toxicity.J Biochem Mol Toxicol202642573050PubTator, text miningPubMed
Cross-Ancestry Proteogenomic Analyses Identified New Therapeutic Insights for Ischemic Heart Disease.J Am Coll Cardiol202642524807PubTator, text miningPubMed
Downregulation of KRTAP2-3 Suppresses Proliferation and Tumor Formation of Oral Cancer Cells via Inactivation of KRAS Signals.Cancer Sci202642482385PubTator, text miningPubMed
Immune parameters correlate with fibrinolysis and predict efficacy of ultrasound-assisted catheter-directed thrombolysis in acute pulmonary embolism.J Thromb Haemost202642480856PubTator, text miningPubMed
Investigating the Causal Role of Inflammatory Cytokines in the Development of Cardiovascular, Kidney, and Metabolic Diseases.Arq Bras Cardiol202642417779PubTator, text miningPubMed
Integrative Genomic Analyses Identify COL21A1 and ENPEP-FGF5 Regulatory Pathways for Blood Pressure Variation in East Asians.bioRxiv202642239286PubTator, text miningPubMed

1 to 10 of 1,455

See all 1,455 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2250

GET https://conductscience.org/api/genes/v1/2250/patents?page=2