Gene · 2253
FGF8: fibroblast growth factor 8
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. FGF8: fibroblast growth factor 8. Genes, record 2253. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2253
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P55075 | Fibroblast growth factor 8 | 233 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents75
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4705273 A2 | 2026-03-11 | 215 | P55075 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 6494 | P55075 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 5293 | P55075 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6379 | P55075 | Espacenet |
| EP 4606428 A2 | 2025-08-27 | 44 | P55075 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6379 | P55075 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 6494 | P55075 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 5293 | P55075 | Espacenet |
| JP 2025013347 A | 2025-01-24 | 215 | P55075 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 5293 | P55075 | Espacenet |
1 to 10 of 75
See all 75 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,059
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | FGF8 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 22 | 2025 |
| R01DE019638 | The role of continuous phenotypic variation in structural defects of the face | 9 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| ZIABC010338 | The Role of Fgf Signaling in Vertebrate Development | 6 | 2025 |
| R35NS116843 | Continuous Neurogenesis in the Mammalian Hippocampus | 5 | 2025 |
| P30CA013330 | Cancer Center Support Grant | 4 | 2025 |
| P30CA014195 | Cancer Center Support Grant (CCSG) | 4 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 4 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 4 | 2025 |
| P51OD011106 | Wisconsin National Primate Research Center Support | 4 | 2025 |
1 to 10 of 2,059Source NIH's project files
See all 2,059 nih grantsPapers3,175
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| FGF/FGFR signaling in hepatocellular carcinoma: From molecular mechanisms to biomarker-guided therapy. | Cancer Treat Res Commun | 2026 | 42753578 | PubTator, text mining | PubMed |
| A Mechanistic Review of Environmental Stressor to Decode Their Effect on Congenital Malformations: A Developmental Toxicity. | J Biochem Mol Toxicol | 2026 | 42573050 | PubTator, text mining | PubMed |
Cellular Logistics and Synaptic Vesicle Vulnerability in Major Depressive Disorder and Amyotrophic Lateral Sclerosis Comorbidity: Insights From Nicotinamide Mononucleotide Rescue and Transcriptome-Wide Association Study Integration. | Cureus | 2026 | 42529685 | PubTator, text mining | PubMed |
| Genome-wide assessment of rare protein-coding variants identifies associations with non-syndromic cleft lip/palate. | Eur J Hum Genet | 2026 | 42477406 | PubTator, text mining | PubMed |
| CRISPR activation of DLX5 drives neural progenitors to the GnRH cell fate. | J Mol Endocrinol | 2026 | 42454502 | PubTator, text mining | PubMed |
| FOXI3 promotes migration and proliferation in prostate cancer bone metastases, modulated by FGF8. | Front Oncol | 2026 | 42394686 | PubTator, text mining | PubMed |
| Combined HS6ST1 and HS6ST2 loss disrupts the formation and migration of gonadotropin-releasing hormone neurons. | Development | 2026 | 42358159 | PubTator, text mining | PubMed |
| FGF8-mediated TRIM16 regulation promotes K48-linked ubiquitination and degradation of RIG-I to facilitate Influenza a virus immune evasion. | Virulence | 2026 | 42171628 | PubTator, text mining | PubMed |
| Identification of two novel PATL2 variants and transcriptome sequencing reveals their role in oocyte maturation. | J Ovarian Res | 2026 | 42063164 | PubTator, text mining | PubMed |
| FGF8 accelerates osteoarthritic chondrocyte hypertrophy by JunB-mediated cytokine perturbation. | Life Sci | 2026 | 41990914 | PubTator, text mining | PubMed |
1 to 10 of 3,175
See all 3,175 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2253
GET https://conductscience.org/api/genes/v1/2253/patents?page=2