Gene · 226
ALDOA: aldolase, fructose-bisphosphate A
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ALDOA: aldolase, fructose-bisphosphate A. Genes, record 226. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/226
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P04075 | Fructose-bisphosphate aldolase A | 364 | 8 | Ensembl, GeneID, HGNC |
Source UniProt
Patents217
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 13041 | P04075 | Espacenet |
| JP 2025169942 A | 2025-11-14 | 787 | P04075 | Espacenet |
| JP 2025169942 A | 2025-11-14 | 788 | P04075 | Espacenet |
| JP 2025169942 A | 2025-11-14 | 790 | P04075 | Espacenet |
| JP 2025169942 A | 2025-11-14 | 791 | P04075 | Espacenet |
| JP 2025169942 A | 2025-11-14 | 793 | P04075 | Espacenet |
| JP 2025157475 A | 2025-10-15 | 63 | P04075 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 707 | P04075 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 708 | P04075 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 709 | P04075 | Espacenet |
1 to 10 of 217
See all 217 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,951
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ALDOA papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 11 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 10 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 5 | 2025 |
| P30DK043351 | Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital | 5 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 5 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 4 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 4 | 2025 |
| P01AG026276 | Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study | 3 | 2025 |
| P20GM103449 | Vermont Biomedical Research Network-Vermont INBRE | 3 | 2025 |
| P30AG066444 | Alzheimer's Disease Research Center | 3 | 2025 |
1 to 10 of 1,951Source NIH's project files
See all 1,951 nih grantsPapers2,824
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| The PKMYT1-ALDOA axis drives chemoresistance in cholangiocarcinoma by enhancing glycolysis and MRE11 lactylation. | Proc Natl Acad Sci U S A | 2026 | 42809391 | PubTator, text mining | PubMed |
| Peritoneal Fluid-Derived Small Extracellular Vesicle Proteins as Potential Biomarkers for Endometriosis: A Case-Control Study. | BJOG | 2026 | 42786124 | PubTator, text mining | PubMed |
| KDM6B inhibition modulates monocyte activation and alleviates IMQ-induced psoriasis-like skin inflammation. | Cell Commun Signal | 2026 | 42732058 | PubTator, text mining | PubMed |
| The KAT2/HDACⅡa-PGK-ALDO axis constitutes a dual degradation inhibition cascade links energy stress to glycolytic amplification. | Proc Natl Acad Sci U S A | 2026 | 42611992 | PubTator, text mining | PubMed |
| The role of mitochondrial energy metabolism in drug resistance and prognosis of lung adenocarcinoma: a multi-omics and machine learning strategy for predictive and personalized therapy. | Front Med (Lausanne) | 2026 | 42601962 | PubTator, text mining | PubMed |
| Metabolic reprogramming is associated with symptomatic COVID-19: a serum proteomics and causal inference study identifying ALDOB and glycerol as candidate metabolic correlates. | Front Microbiol | 2026 | 42568671 | PubTator, text mining | PubMed |
| Epitranscriptomic Regulation of ALDOA by SHMT2-Mediated m6A Modification Drives Gastric Cancer Malignancy. | Mol Carcinog | 2026 | 42541491 | PubTator, text mining | PubMed |
| Label-free detection of glioma radioresistance using exosomal SERS spectra and machine learning. | Biosens Bioelectron | 2026 | 42497545 | PubTator, text mining | PubMed |
| Integrative analysis identifies ALDOA and PGK1 as prognostic biomarkers and therapeutic targets in oral squamous cell carcinoma. | Discov Oncol | 2026 | 42463560 | PubTator, text mining | PubMed |
| The ubiquitin ligase LONRF2 inhibits glycolysis and malignant phenotypes in endometrial cancer through aldolase a degradation. | J Biol Chem | 2026 | 42442502 | PubTator, text mining | PubMed |
1 to 10 of 2,824
See all 2,824 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/226
GET https://conductscience.org/api/genes/v1/226/patents?page=2