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FGFR1: fibroblast growth factor receptor 1

1 protein, 164 patents, 29 drugs, 866 trials, 6,410 NIH grants and 16,642 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolFGFR1HGNC
Namefibroblast growth factor receptor 1HGNC
NCBI Gene ID2260NCBI Gene
HGNC IDHGNC:3688HGNC
EnsemblENSG00000077782NCBI Gene
AliasesBFGFR, CD331, CEK, ECCL, FGFBR, FGFR-1, FLG, FLT-2, FLT2, H2, H3, H4, H5, HBGFR, HH2, HRTFDS, KAL2, N-SAM, OGD, bFGF-R-1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P11362Fibroblast growth factor receptor 182283Ensembl, GeneID, HGNCUniProt

Patents 164

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026511570 A2026-04-1432P11362Espacenet
JP 2026004568 A2026-01-1446240P11362Espacenet
EP 4670728 A12025-12-3132P11362Espacenet
WO 2025247951 A12025-12-0414P11362Espacenet
KR 1020250166953 A2025-11-2832P11362Espacenet
EP 4650780 A22025-11-1913019P11362Espacenet
EP 4641201 A22025-10-2914638P11362Espacenet
EP 4641202 A22025-10-29783P11362Espacenet
EP 4641203 A22025-10-29449P11362Espacenet
JP 2025147176 A2025-10-065310P11362Espacenet

Drugs 29

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
BRIVANIBCHEMBL377300Fibroblast growth factor receptor inhibitorINHIBITORChEMBL
BRIVANIB ALANINATECHEMBL270995Fibroblast growth factor receptor inhibitorINHIBITORChEMBL
CP-459632CHEMBL3545300Fibroblast growth factor receptor inhibitorINHIBITORChEMBL
DERAZANTINIBCHEMBL4297187Fibroblast growth factor receptor inhibitorINHIBITORChEMBL
E-7090CHEMBL3686884Fibroblast growth factor receptor 1 inhibitorINHIBITORChEMBL
ENMD-981693CHEMBL52885Fibroblast growth factor receptor inhibitorINHIBITORChEMBL
ERDAFITINIBCHEMBL3545376Fibroblast growth factor receptor inhibitorINHIBITORChEMBL
FEXAGRATINIBCHEMBL3348846Fibroblast growth factor receptor inhibitorINHIBITORChEMBL
FGFR INHIBITOR DEBIO 1347CHEMBL3907479Fibroblast growth factor receptor 1 inhibitorINHIBITORChEMBL
FUTIBATINIBCHEMBL3701238Fibroblast growth factor receptor inhibitorINHIBITORChEMBL

Trials 866

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07594548FUTIBATINIBPHASE1ClinicalTrials.gov
NCT07583589NINTEDANIBPHASE2ClinicalTrials.gov
NCT07559864REGORAFENIBPHASE2ClinicalTrials.gov
NCT07537985REGORAFENIBClinicalTrials.gov
NCT07534371SURUFATINIBClinicalTrials.gov
NCT07514455REGORAFENIBPHASE2ClinicalTrials.gov
NCT07514429REGORAFENIBPHASE2ClinicalTrials.gov
NCT07505472SURUFATINIBPHASE2/PHASE3ClinicalTrials.gov
NCT07501351REGORAFENIBPHASE2ClinicalTrials.gov
NCT07495579REGORAFENIBPHASE2ClinicalTrials.gov

NIH grants 6410

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant2032,025NIH's project files
P30CA016672Cancer Center Support Grant1942,025NIH's project files
P30CA006973Regional Oncology Research Center432,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant422,025NIH's project files
P30CA068485Cancer Center Support Grant312,025NIH's project files
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant292,025NIH's project files
P30CA047904Cancer Center Support Grant262,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award252,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant232,025NIH's project files
P30CA016058Cancer Center Support Grant232,025NIH's project files

Papers 16642

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825310PubTator, text miningPubMed
42820258PubTator, text miningPubMed
42819076PubTator, text miningPubMed
42794696PubTator, text miningPubMed
42786427PubTator, text miningPubMed
42769056PubTator, text miningPubMed
42744759PubTator, text miningPubMed
42741478PubTator, text miningPubMed
42728926PubTator, text miningPubMed
42724722PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license