Gene · 22806
IKZF3: IKAROS family zinc finger 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. IKZF3: IKAROS family zinc finger 3. Genes, record 22806. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/22806
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9UKT9 | Zinc finger protein Aiolos | 509 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents64
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4781985 A2 | 2026-07-29 | 12 | Q9UKT9 | Espacenet |
| JP 2026048701 A | 2026-03-17 | 328 | Q9UKT9 | Espacenet |
| JP 2026505349 A | 2026-02-13 | 2 | Q9UKT9 | Espacenet |
| JP 2026502937 A | 2026-01-27 | 12 | Q9UKT9 | Espacenet |
| JP 2026501039 A | 2026-01-14 | 12 | Q9UKT9 | Espacenet |
| WO 2025226767 A1 | 2025-10-30 | 12 | Q9UKT9 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 6735 | Q9UKT9 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 5189 | Q9UKT9 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15164 | Q9UKT9 | Espacenet |
| KR 1020250138280 A | 2025-09-19 | 2 | Q9UKT9 | Espacenet |
1 to 10 of 64
See all 64 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,840
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | IKZF3 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 19 | 2025 |
| P50CA186781 | Mayo Clinic Multiple Myeloma SPORE | 16 | 2025 |
| R01CA214608 | The molecular basis of IMiD induced neo-substrate recruitment to the CRL4CRBN ubiquitin E3 ligase | 16 | 2025 |
| P01CA066996 | Development of Novel Therapeutic Strategies in Human Leukemias | 15 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 11 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 10 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 9 | 2025 |
| R01CA218278 | Degrading therapeutically important kinases using small molecules | 9 | 2025 |
| P01CA155258 | Integrative Oncogenomics of Multiple Myeloma | 7 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 7 | 2025 |
1 to 10 of 1,840Source NIH's project files
See all 1,840 nih grantsPapers2,106
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Multi-Ancestry Genome-wide Association Analyses Identify Shared and Specific Genetic Architecture in Mild and Moderate-to-Severe Asthma. | medRxiv | 2026 | 42818167 | PubTator, text mining | PubMed |
| Associations of ASIC2, IKZF3, and GSDMB Variants with Gestational Diabetes Mellitus and Their Interactions with Environmental Exposures Among Chinese Women. | Biomolecules | 2026 | 42793205 | PubTator, text mining | PubMed |
| Genetically Predicted Gene Expression and Circulating Metabolites Associated with Cervical High-Grade Squamous Intraepithelial Lesion: A Mendelian Randomization Study. | Int J Womens Health | 2026 | 42701819 | PubTator, text mining | PubMed |
| CXXC1-dependent IRF4 activity promotes myeloma cell fitness and sustains lenalidomide resistance. | Blood | 2026 | 42685001 | PubTator, text mining | PubMed |
| Discovery of BMS-986449: A Potent, Selective Degrader of the Transcription Factors IKZF2 (Helios) and IKZF4 (Eos) to Target Regulatory T Cells in Solid Tumors. | J Med Chem | 2026 | 42677819 | PubTator, text mining | PubMed |
| Proteomic Insights Into Human Induced Regulatory T Cells: The Role of LPXN and CD160 in Immune Suppression. | Mol Cell Proteomics | 2026 | 42624209 | PubTator, text mining | PubMed |
| Identification of genetic variants associated with idiopathic inflammatory myopathies via cross-trait analysis with B cell lymphomas. | HGG Adv | 2026 | 42499187 | PubTator, text mining | PubMed |
| IL-7-glucose-Aiolos axis orchestrates pathogenic CD8+ T cell function in spondyloarthritis. | Proc Natl Acad Sci U S A | 2026 | 42461767 | PubTator, text mining | PubMed |
| Oncogenic DNMT3B as a therapeutic target for cervical cancer. | Chin Med J (Engl) | 2026 | 42402721 | PubTator, text mining | PubMed |
| Identification of XZ8078 as a Dual-Target Degrader Targeting PARP1 and IKZF3 for Broad Spectrum Anticancer Treatment. | J Med Chem | 2026 | 42380731 | PubTator, text mining | PubMed |
1 to 10 of 2,106
See all 2,106 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/22806
GET https://conductscience.org/api/genes/v1/22806/patents?page=2