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Gene · 22858

CILK1: ciliogenesis associated kinase 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CILK1: ciliogenesis associated kinase 1. Genes, record 22858. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/22858

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Gene

Symbol
CILK1
HGNC
Name
ciliogenesis associated kinase 1
HGNC
NCBI Gene ID
22858
NCBI Gene
HGNC ID
HGNC:21219
HGNC
Ensembl
ENSG00000112144
NCBI Gene
Aliases
CED6, ECO, EJM10, ICK, KIAA0936, LCK2, MGC46090, MRK, hICK
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9UPZ9Serine/threonine-protein kinase ICK6320Ensembl, GeneID, HGNC

Source UniProt

Patents42

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1450322Q9UPZ9Espacenet
JP 2026004568 A2026-01-1450323Q9UPZ9Espacenet
US 11446398 B22022-09-2041778Q9UPZ9Espacenet
US 11446398 B22022-09-2041779Q9UPZ9Espacenet
JP 2022524081 A2022-04-27144749Q9UPZ9Espacenet
JP 2022524081 A2022-04-27144750Q9UPZ9Espacenet
US 11078247 B22021-08-035284Q9UPZ9Espacenet
EP 3504344 A12019-07-03124Q9UPZ9Espacenet
JP 2019054813 A2019-04-11230757Q9UPZ9Espacenet
JP 2019054813 A2019-04-11230758Q9UPZ9Espacenet

1 to 10 of 42

See all 42 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,094

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCILK1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant152025
P30CA016672Cancer Center Support Grant62025
P01CA092584Structural Cell Biology of DNA Repair Machines52025
R01CA235152Smart nanoparticles regulating oncogenic IncRNA for breast cancer therapy52025
P30CA006973Regional Oncology Research Center32025
P30CA043703Case Comprehensive Cancer Center Support Grant32025
P30CA068485Cancer Center Support Grant32025
P01CA163227Androgen Receptor Action in Castration Resistant Prostate Cancer22025
P30CA014520UW Comprehensive Cancer Center Support22025
P30CA016520Abramson Cancer Center Support Grant22025

1 to 10 of 1,094Source NIH's project files

See all 1,094 nih grants

Papers2,020

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Deletion of TaBSK3-2B attenuates BR signaling to regulate the Rht4 semi-dwarf phenotype and drought tolerance in wheat.Plant J202642750658PubTator, text miningPubMed
Revealing Causal Proteomic Signatures of Hypertension: Systematic Insights From Proteome-Wide Mendelian Randomization.Hypertension202642713651PubTator, text miningPubMed
Genetic insights into bacterial wilt resistance using genomic prediction and association mapping in blueberry.Plant Genome202642625244PubTator, text miningPubMed
In silico DFT study, molecular docking interactions, molecular dynamics and toxicological assessment of selected organochlorine-based pesticides.In Silico Pharmacol202642542631PubTator, text miningPubMed
Resistance to the oat leaf blotch pathogen (Pyrenophora avenae) is delimited to a region of chromosome 1D that harbors a candidate resistance kinase fusion protein.Theor Appl Genet202642496734PubTator, text miningPubMed
LlSAPK2 confers thermotolerance in lily by phosphorylating and stabilizing LlbZIP46.J Integr Plant Biol202642317057PubTator, text miningPubMed
Tipping the balance: synthesis and evaluation of centrinone-based degraders of polo-like kinase 4.RSC Chem Biol202642220890PubTator, text miningPubMed
Human Cytomegalovirus Infection in Haematopoietic Stem Cell Transplant Recipients and CAR-T Cell Recipients-PART 2: Antiviral Therapy and Virus-Specific T Cell Therapy for HCMV in Allo-HSCT.Rev Med Virol202641914212PubTator, text miningPubMed
Crude Venom from Sea Anemone Macrodactyla doreensis Suppresses Glioblastoma via the p53 Pathway.Mar Drugs202641892951PubTator, text miningPubMed
Recent Progress and Morphological Distribution of Polydopamine-Based Biomaterials and Their Applications.Gels202641892510PubTator, text miningPubMed

1 to 10 of 2,020

See all 2,020 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/22858

GET https://conductscience.org/api/genes/v1/22858/patents?page=2