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Gene · 22863

ATG14: autophagy related 14

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ATG14: autophagy related 14. Genes, record 22863. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/22863

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Gene

Symbol
ATG14
HGNC
Name
autophagy related 14
HGNC
NCBI Gene ID
22863
NCBI Gene
HGNC ID
HGNC:19962
HGNC
Ensembl
ENSG00000126775
NCBI Gene
Aliases
ATG14L, BARKOR, KIAA0831
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q6ZNE5Beclin 1-associated autophagy-related key regulator4926Ensembl, GeneID, HGNC

Source UniProt

Patents15

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-191219Q6ZNE5Espacenet
JP 2025517970 A2025-06-121219Q6ZNE5Espacenet
JP 2025062604 A2025-04-147982Q6ZNE5Espacenet
US 11446398 B22022-09-207982Q6ZNE5Espacenet
JP 2022524081 A2022-04-27110953Q6ZNE5Espacenet
JP 2017121240 A2017-07-1348503Q6ZNE5Espacenet
JP 2015518704 A2015-07-0648503Q6ZNE5Espacenet
US 8647822 B22014-02-1144Q6ZNE5Espacenet
US 8586006 B22013-11-196159Q6ZNE5Espacenet
EP 2616082 A22013-07-2424Q6ZNE5Espacenet

1 to 10 of 15

See all 15 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,297

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleATG14 papersNewest fiscal year
R01CA126792Autophagy and Pro-metastatic Differentiation132025
R01NS060123Neuronal Autophagy: a Cell-Autonomous Protection Mechanism122025
P20GM121176Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2.92025
P30CA016672Cancer Center Support Grant92025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital82025
R37AI042999Pattern Recognition Receptors and Autophagy in Mtb Control in AIDS82025
R01HL091469Cysteine oxidation in the heart72025
R35GM131919The mechanism and regulation of autophagy72025
R01AG057462Endolysosomal defects in secretory autophagy and microglial toxicity in FTD62025
R01CA200310BNIP3 and BNIP3L (NIX) in lipid homeostasis and growth control in the liver52025

1 to 10 of 1,297Source NIH's project files

See all 1,297 nih grants

Papers2,687

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Avobenzone induces intestinal injury by targeting ATG14 and impairing mitophagy.Cell Commun Signal202642806331PubTator, text miningPubMed
Prevotella histicola improves metabolic-associated fatty liver disease by promoting lipid droplet autophagy and inhibiting ER stress.Biochim Biophys Acta Mol Cell Res202642767428PubTator, text miningPubMed
BAP31 Drives Cartilage Calcification through Disruption of Autophagosome-Lysosome Fusion in Osteoarthritis.Adv Sci (Weinh)202642666098PubTator, text miningPubMed
The glycolytic enzyme PGAM1 functions as a metabolic-autophagy checkpoint to coordinate growth and stress tolerance.Nat Cell Biol202642527668PubTator, text miningPubMed
AARS2-mediated lactylation of ULK1 promotes autophagy-dependent progression of clear cell renal cell carcinoma.Autophagy202642381569PubTator, text miningPubMed
Ferulic Acid Prevents the Hepatotoxicity of AFB1 on Broilers via Regulating Autophagy.Vet Sci202642357747PubTator, text miningPubMed
MicroRNAs and predicted targets in the switch from monolayered to spheroids of cholangiocarcinoma cells.Exp Mol Pathol202642330787PubTator, text miningPubMed
Correction to "ATG14-Mediated SNARE Complex Activation Promotes ΔFosB Degradation to Ameliorate Levodopa-Induced Dyskinesia".J Neurochem202642299747PubTator, text miningPubMed
A novel RAB5 binding site in human VPS34-CII that is likely the primordial site in eukaryotic evolution.Elife202642207670PubTator, text miningPubMed
TRP53/p53 protects adult hippocampal neural stem cells from psychological stress by preventing autophagic cell death.Autophagy202642152468PubTator, text miningPubMed

1 to 10 of 2,687

See all 2,687 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/22863

GET https://conductscience.org/api/genes/v1/22863/patents