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ZHX2: zinc fingers and homeoboxes 2

1 protein, 33 patents, 0 drugs, 0 trials, 12,426 NIH grants and 32,209 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolZHX2HGNC
Namezinc fingers and homeoboxes 2HGNC
NCBI Gene ID22882NCBI Gene
HGNC IDHGNC:18513HGNC
EnsemblENSG00000178764NCBI Gene
AliasesAFR1, KIAA0854, RAFNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q9Y6X8Zinc fingers and homeoboxes protein 28372Ensembl, GeneID, HGNCUniProt

Patents 33

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-194970Q9Y6X8Espacenet
EP 4641201 A22025-10-294554Q9Y6X8Espacenet
JP 2025147176 A2025-10-0615947Q9Y6X8Espacenet
JP 2025517969 A2025-06-124554Q9Y6X8Espacenet
JP 2025517970 A2025-06-124970Q9Y6X8Espacenet
JP 2025028160 A2025-02-2815947Q9Y6X8Espacenet
KR 1020250010750 A2025-01-2115947Q9Y6X8Espacenet
JP 2024109657 A2024-08-1415786Q9Y6X8Espacenet
JP 2023552307 A2023-12-1524Q9Y6X8Espacenet
KR 1020230121064 A2023-08-1724Q9Y6X8Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 12426

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant4262,025NIH's project files
P30CA008748Cancer Center Support Grant3772,025NIH's project files
P30CA006973Regional Oncology Research Center752,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant672,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase602,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant542,025NIH's project files
P30CA016058Cancer Center Support Grant532,025NIH's project files
P30CA068485Cancer Center Support Grant462,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award462,025NIH's project files
ZIABC010441Biomolecular Recognition and Binding Mechanisms462,025NIH's project files

Papers 32209

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826809PubTator, text miningPubMed
42826365PubTator, text miningPubMed
42825158PubTator, text miningPubMed
42824816PubTator, text miningPubMed
42820076PubTator, text miningPubMed
42814864PubTator, text miningPubMed
42814800PubTator, text miningPubMed
42810411PubTator, text miningPubMed
42808379PubTator, text miningPubMed
42807131PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license