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Gene · 2289

FKBP5: FKBP prolyl isomerase 5

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. FKBP5: FKBP prolyl isomerase 5. Genes, record 2289. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/2289

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
FKBP5
HGNC
Name
FKBP prolyl isomerase 5
HGNC
NCBI Gene ID
2289
NCBI Gene
HGNC ID
HGNC:3721
HGNC
Ensembl
ENSG00000096060
NCBI Gene
Aliases
AIG6, FKBP51, FKBP54, P54, PPIase, Ptg-10
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q13451Peptidyl-prolyl cis-trans isomerase FKBP5457138Ensembl, GeneID, HGNC

Source UniProt

Patents77

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1446389Q13451Espacenet
JP 2026004568 A2026-01-1446390Q13451Espacenet
JP 2026004568 A2026-01-1446392Q13451Espacenet
JP 2026004568 A2026-01-1446393Q13451Espacenet
EP 4650780 A22025-11-197414Q13451Espacenet
EP 4641201 A22025-10-297367Q13451Espacenet
EP 4641202 A22025-10-295264Q13451Espacenet
US 12409182 B22025-09-091Q13451Espacenet
JP 2025517969 A2025-06-127367Q13451Espacenet
JP 2025517970 A2025-06-127414Q13451Espacenet

1 to 10 of 77

See all 77 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants3,378

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA008748Cancer Center Support Grant282025
P50CA097186The Pacific Northwest Prostate Cancer SPORE282025
ZIAAA000301Integrative genetics of behavior with high throughput technologies232025
P01CA163227Androgen Receptor Action in Castration Resistant Prostate Cancer192025
P50CA092629SPORE in Prostate Cancer152025
R01NS073899The hsp90 Cochaperone FKBP51 Regulates tau Structure and Function152025
P30CA016056Roswell Park Cancer Center Support Grant122025
R01CA174777AR Gene Rearrangements and AR Signaling in Prostate Cancer112025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant102025
UL1TR001863Yale Clinical and Translational Science Award102025

1 to 10 of 3,378Source NIH's project files

See all 3,378 nih grants

Papers4,216

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42817405PubTator, text miningPubMed
42804337PubTator, text miningPubMed
42802518PubTator, text miningPubMed
42800174PubTator, text miningPubMed
42792815PubTator, text miningPubMed
42785232PubTator, text miningPubMed
42710613PubTator, text miningPubMed
42709166PubTator, text miningPubMed
42707746PubTator, text miningPubMed
42699379PubTator, text miningPubMed

1 to 10 of 4,216

See all 4,216 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/2289

GET https://conductscience.org/api/genes/v1/2289/patents?page=2